6T2K

Name : Furano[2,3-d]prymidine amides as human Notum inhibitors 2 (LP-922056)

Revelation date : 01-Jan-2020

Family : Pectinacetylesterase-Notum

Gene_locus : human-NOTUM

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Zhao, Y., Jones, E.Y.

Ligand :

References (1)

Title : Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors - Atkinson_2019_Bioorg.Med.Chem.Lett__126751
Author(s) : Atkinson BN , Steadman D , Mahy W , Zhao Y , Sipthorp J , Bayle ED , Svensson F , Papageorgiou G , Jeganathan F , Frew S , Monaghan A , Bictash M , Jones EY , Fish PV
Ref : Bioorganic & Medicinal Chemistry Lett , :126751 , 2019
PubMedID: 31862412
Gene_locus related to this paper: human-NOTUM

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 6T2K Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6T2K Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6T2K Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6T2K 3D, interactive encyclopedia of proteins - PROTEOPEDIA server