7B3F

Name : Human Notum S232A in complex with ARUK3003718 compound 2 acid

Revelation date : 04-Aug-2021

Family : Pectinacetylesterase-Notum

Gene_locus : human-NOTUM

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Zhao, Y.,Jones, E.Y.

Ligand : Inhibitor ARUK3003718 Ligand in structure: Ligplot

References (1)

Title : Structural Insights into Notum Covalent Inhibition - Zhao_2021_J.Med.Chem_64_11354
Author(s) : Zhao Y , Svensson F , Steadman D , Frew S , Monaghan A , Bictash M , Moreira T , Chalk R , Lu W , Fish PV , Jones EY
Ref : Journal of Medicinal Chemistry , 64 :11354 , 2021
Abstract :
PubMedSearch : Zhao_2021_J.Med.Chem_64_11354
PubMedID: 34292747
Gene_locus related to this paper: human-NOTUM

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 7B3F Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 7B3F Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 7B3F Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 7B3F 3D, interactive encyclopedia of proteins - PROTEOPEDIA server