8UWM
Name : FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, borolane-based compound Q41 bound
Revelation date : 20-Nov-2024
Family : 6_AlphaBeta_hydrolase
Gene_locus : staau-SA2367
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Fellner, M.
References (3)
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 8UWM Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 8UWM Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 8UWM Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 8UWM 3D, interactive encyclopedia of proteins - PROTEOPEDIA server