9GOC

Name : Crystal structure of DPP9 Ser730Ala in complex with sulphostin

Revelation date : na

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP9

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Sewald, L.,Tabak, W.W.A.,Fehr, L.,Zolg, S.,Najdzion, M.,Verhoef, C.J.A.,Podlesainski, D.,Geiss-Friedlander, R.,Lammens, A.,Kaschani, F.,Hellerschmied, D.,Huber, R.,Kaiser, M.

Ligand : Inhibitor Sulphostin Ligand in structure: Ligplot

References (1)

Title : Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors - Sewald_2025_Nat.Commun_16_3208
Author(s) : Sewald L , Tabak WWA , Fehr L , Zolg S , Najdzion M , Verhoef CJA , Podlesainski D , Geiss-Friedlander R , Lammens A , Kaschani F , Hellerschmied D , Huber R , Kaiser M
Ref : Nat Commun , 16 :3208 , 2025
Abstract :
PubMedSearch : Sewald_2025_Nat.Commun_16_3208
PubMedID: 40180908
Gene_locus related to this paper: human-DPP4 , human-DPP8 , human-DPP9

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 9GOC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 9GOC Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 9GOC Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 9GOC 3D, interactive encyclopedia of proteins - PROTEOPEDIA server