Name : Crystal structure of DPP9 Ser730Ala in complex with sulphostin
Revelation date : na
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP9
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Sewald, L.,Tabak, W.W.A.,Fehr, L.,Zolg, S.,Najdzion, M.,Verhoef, C.J.A.,Podlesainski, D.,Geiss-Friedlander, R.,Lammens, A.,Kaschani, F.,Hellerschmied, D.,Huber, R.,Kaiser, M.
Ligand : Inhibitor Sulphostin Ligand in structure: Ligplot
Title : Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors - Sewald_2025_Nat.Commun_16_3208 |
Author(s) : Sewald L , Tabak WWA , Fehr L , Zolg S , Najdzion M , Verhoef CJA , Podlesainski D , Geiss-Friedlander R , Lammens A , Kaschani F , Hellerschmied D , Huber R , Kaiser M |
Ref : Nat Commun , 16 :3208 , 2025 |
Abstract : |
PubMedSearch : Sewald_2025_Nat.Commun_16_3208 |
PubMedID: 40180908 |
Gene_locus related to this paper: human-DPP4 , human-DPP8 , human-DPP9 |
PDB-Sum : 9GOC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9GOC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9GOC Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9GOC 3D, interactive encyclopedia of proteins - PROTEOPEDIA server