human-DPP9

Homo sapiens (Human) dipeptidyl peptidase 9 DPP9 DPRP2

Comment

DPP8 and DPP9 are cytosolic peptidases. Have dpp activity similar to dpp4. The first identified endogenous DPP9 substrate is the tumor epitope RU1(34-42) (VPYGSFKHV). Inhibition or silencing of DPP9, but not DPP8, led to increased presentation of this antigen on MHC class I alleles to cytotoxic T-cells, linking DPP9 to the MHC class I antigen presentation pathway. Small ubiquitin-like protein modifier SUMO1 acts as an allosteric activator of DPP9. By binding to an armlike motif in DPP9\; DPP9 functions as an endogenous inhibitor of NLRP1 inflammasome. DPP9 interacts with a unique autoproteolytic domain (Function to Find Domain (FIIND)) found in NLRP1 and CARD8. Hatipoglu immunodeficiency syndrome\; HATIS. The symptoms associated with this monogenic disease partially overlapped with those of AIADK caused by an NLRP1 gain-of-function mutation. These included failure to thrive (consisting of poor weight gain,growing below the third percentile),skin manifestations, pancytopenia, and susceptibility to infections, which required hematopoietic stem cell transplant. The stop-gain mutations were expected to completely abolish the enzymatic activity of DPP9.

Relationship

Family : DPP4N_Peptidase_S9

Block : X

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Database

Sequence

Peptide

RRVPCVRRGC RPPLPPLPGS QSRAWSRDRE APLDPGRPAQ SGRRPTSRSV SHACSWNGGS LDPLEGTPAL LRSAERLMRK VKKLRLDKEN TGSWRSFSLN SEGAERMATT GTPTADRGDA AATDDPAARF QVQKHSWDGL RSIIHGSRKY SGLIVNKAPH DFQFVQKTDE SGPHSHRLYY LGMPYGSREN SLLYSEIPKK VRKEALLLLS WKQMLDHFQA TPHHGVYSRE EELLRERKRL GVFGITSYDF HSESGLFLFQ ASNSLFHCRD GGKNGFMVSP MKPLEIKTQC SGPRMDPKIC PADPAFFSFN NNSDLWVANI ETGEERRLTF CHQGLSNVLD DPKSAGVATF VIQEEFDRFT GYWWCPTASW EGSEGLKTLR ILYEEVDESE VEVIHVPSPA LEERKTDSYR YPRTGSKNPK IALKLAEFQT DSQGKIVSTQ EKELVQPFSS LFPKVEYIAR AGWTRDGKYA WAMFLDRPQQ WLQLVLLPPA LFIPSTENEE QRLASARAVP RNVQPYVVYE EVTNVWINVH DIFYPFPQSE GEDELCFLRA NECKTGFCHL YKVTAVLKSQ GYDWSEPFSP GEDEFKCPIK EEIALTSGEW EVLARHGSKI WVNEETKLVY FQGTKDTPLE HHLYVVSYEA AGEIVRLTTP GFSHSCSMSQ NFDMFVSHYS SVSTPPCVHV YKLSGPDDDP LHKQPRFWAS MMEAASCPPD YVPPEIFHFH TRSDVRLYGM IYKPHALQPG KKHPTVLFVY GGPQVQLVNN SFKGIKYLRL NTLASLGYAV VVIDGRGSCQ RGLRFEGALK NQMGQVEIED QVEGLQFVAE KYGFIDLSRV AIHGWSYGGF LSLMGLIHKP QVFKVAIAGA PVTVWMAYDT GYTERYMDVP ENNQHGYEAG SVALHVEKLP NEPNRLLILH GFLDENVHFF HTNFLVSQLI RAGKPYQLQI YPNERHSIRC PESGEHYEVT LLHFLQEYL

References (49)

Title : Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer - Hess_2024_Biochim.Biophys.Acta.Mol.Basis.Dis__167133
Author(s) : Hess L , Aliar K , Grunwald BT , Griffin R , Lozan A , Knoller M , Khokha R , Brummer T , Reinheckel T
Ref : Biochimica & Biophysica Acta Mol Basis Dis , :167133 , 2024
PubMedID: 38531482
Gene_locus related to this paper: human-DPP9 , mouse-dpp9

Title : Non-Specific Inhibition of Dipeptidyl Peptidases 8\/9 by Dipeptidyl Peptidase 4 Inhibitors Negatively Affects Mesenchymal Stem Cell Differentiation - Torrecillas-Baena_2023_J.Clin.Med_12_4632
Author(s) : Torrecillas-Baena B , Camacho-Cardenosa M , Quesada-Gomez JM , Moreno-Moreno P , Dorado G , Galvez-Moreno M , Casado-Diaz A
Ref : J Clin Med , 12 :4632 , 2023
PubMedID: 37510747
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Structural and Biochemical Insights into Bis(2-hydroxyethyl) Terephthalate Degrading Carboxylesterase Isolated from Psychrotrophic Bacterium Exiguobacterium antarcticum - Hwang_2023_Int.J.Mol.Sci_24_12022
Author(s) : Hwang J , Yoo W , Shin SC , Kim KK , Kim HW , Do H , Lee JH
Ref : Int J Mol Sci , 24 :12022 , 2023
PubMedID: 37569396
Gene_locus related to this paper: human-DPP9 , exiab-k0afs0

Title : DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma - Chang_2023_Cancer.Res__
Author(s) : Chang K , Chen Y , Zhang X , Zhang W , Xu N , Zeng B , Wang Y , Feng T , Dai B , Xu F , Ye D , Wang C
Ref : Cancer Research , : , 2023
PubMedID: 37713596
Gene_locus related to this paper: human-DPP9

Title : A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells - Moore_2022_ACS.Chem.Biol_17_2595
Author(s) : Moore KP , Schwaid AG , Tudor M , Park S , Beshore DC , Converso A , Shipe WD , Anand R , Lan P , Moningka R , Rothman DM , Sun W , Chi A , Cornella-Taracido I , Adam GC , Bahnck-Teets C , Carroll SS , Fay JF , Goh SL , Lusen J , Quan S , Rodriguez S , Xu M , Andrews CL , Song C , Filzen T , Li J , Hollenstein K , Klein DJ , Lammens A , Lim UM , Fang Z , McHale C , Li Y , Lu M , Diamond TL , Howell BJ , Zuck P , Balibar CJ
Ref : ACS Chemical Biology , 17 :2595 , 2022
PubMedID: 36044633
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 - Carvalho_2022_Angew.Chem.Int.Ed.Engl_61_e202210498
Author(s) : Carvalho LAR , Ross B , Fehr L , Bolgi O , Wohrle S , Lum KM , Podlesainski D , Vieira AC , Kiefersauer R , Felix R , Rodrigues T , Lucas SD , Gross O , Geiss-Friedlander R , Cravatt BF , Huber R , Kaiser M , Moreira R
Ref : Angew Chem Int Ed Engl , : , 2022
PubMedID: 36089535
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors - Cui_2022_Front.Pharmacol_13_1002871
Author(s) : Cui C , Tian X , Wei L , Wang Y , Wang K , Fu R
Ref : Front Pharmacol , 13 :1002871 , 2022
PubMedID: 36172198
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair - Bolgi_2022_EMBO.Rep__e54136
Author(s) : Bolgi O , Silva-Garcia M , Ross B , Pilla E , Kari V , Killisch M , Spitzner M , Stark N , Lenz C , Weiss K , Donzelli L , Gorrell MD , Grade M , Riemer J , Urlaub H , Dobbelstein M , Huber R , Geiss-Friedlander R
Ref : EMBO Rep , :e54136 , 2022
PubMedID: 35912982
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1\/IL-1 signaling - Harapas_2022_Sci.Immunol_7_eabi4611
Author(s) : Harapas CR , Robinson KS , Lay K , Wong J , Moreno Traspas R , Nabavizadeh N , Rass-Rothschild A , Boisson B , Drutman SB , Laohamonthonkul P , Bonner D , Xiong JR , Gorrell MD , Davidson S , Yu CH , Fleming MD , Gudera J , Stein J , Ben-Harosh M , Groopman E , Shimamura A , Tamary H , Kayserili H , Hatipoglu N , Casanova JL , Bernstein JA , Zhong FL , Masters SL , Reversade B
Ref : Sci Immunol , 7 :eabi4611 , 2022
PubMedID: 36112693
Gene_locus related to this paper: human-DPP9

Title : Profibrotic mechanisms of DPP8 and DPP9 highly expressed in the proximal renal tubule epithelial cells - Zhang_2021_Pharmacol.Res_169_105630
Author(s) : Zhang Y , Li K , Li Y , Zhao W , Wang L , Chen Z , Ma X , Yao T , Wang J , Dong W , Li X , Tian X , Fu R
Ref : Pharmacol Res , 169 :105630 , 2021
PubMedID: 33932609
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation - Hollingsworth_2021_Nature_592_778
Author(s) : Hollingsworth LR , Sharif H , Griswold AR , Fontana P , Mintseris J , Dagbay KB , Paulo JA , Gygi SP , Bachovchin DA , Wu H
Ref : Nature , 592 :778 , 2021
PubMedID: 33731932
Gene_locus related to this paper: human-DPP9

Title : Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment - Sharif_2021_Immunity__
Author(s) : Sharif H , Hollingsworth LR , Griswold AR , Hsiao JC , Wang Q , Bachovchin DA , Wu H
Ref : Immunity , : , 2021
PubMedID: 34019797
Gene_locus related to this paper: human-DPP9

Title : Structural mechanism of CARD8 regulation by DPP9 - Sharif_2021_Biorxiv__
Author(s) : Sharif H , Hollingsworth LR , Griswold AR , Hsiao JC , Wang QH , Bachovchin DA , Wu H
Ref : Biorxiv , : , 2021
PubMedID:
Gene_locus related to this paper: human-DPP9

Title : Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair - Silva-Garcia_2020_Biorxiv__
Author(s) : Silva-Garcia M , Bolgi O , Ross B , Pilla E , Kari V , Killisch M , Stark N , Lenz C , Spitzner M , Gorrell MD , Grade M , Urlaub H , Dobbelstein M , Huber R , Geiss-Friedlander R
Ref : Biorxiv , : , 2020
PubMedID:
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Activation of the CARD8 Inflammasome Requires a Disordered Region - Chui_2020_Cell.Rep_33_108264
Author(s) : Chui AJ , Griswold AR , Taabazuing CY , Orth EL , Gai K , Rao SD , Ball DP , Hsiao JC , Bachovchin DA
Ref : Cell Rep , 33 :108264 , 2020
PubMedID: 33053349
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation - Hollingsworth_2020_Biorxiv__
Author(s) : Hollingsworth LR , Sharif H , Griswold AR , Fontana P , Mintseris J , Dagbay KB , Paulo JA , Gygi SP , Bachovchin DA , Wu
Ref : Biorxiv , : , 2020
PubMedID:
Gene_locus related to this paper: human-DPP9

Title : CARD8 inflammasome activation triggers pyroptosis in human T cells - Linder_2020_EMBO.J__e105071
Author(s) : Linder A , Bauernfried S , Cheng Y , Albanese M , Jung C , Keppler OT , Hornung V
Ref : EMBO Journal , :e105071 , 2020
PubMedID: 32840892
Gene_locus related to this paper: human-DPP9

Title : The NLRP1 and CARD8 inflammasomes - Taabazuing_2020_Immunol.Rev_297_13
Author(s) : Taabazuing CY , Griswold AR , Bachovchin DA
Ref : Immunol Rev , 297 :13 , 2020
PubMedID: 32558991
Gene_locus related to this paper: human-DPP9

Title : Proteasomal degradation induced by DPP9-mediated processing competes with mitochondrial protein import - Finger_2020_EMBO.J__e103889
Author(s) : Finger Y , Habich M , Gerlich S , Urbanczyk S , van de Logt E , Koch J , Schu L , Lapacz KJ , Ali M , Petrungaro C , Salscheider SL , Pichlo C , Baumann U , Mielenz D , Dengjel J , Brachvogel B , Hofmann K , Riemer J
Ref : EMBO Journal , :e103889 , 2020
PubMedID: 32815200
Gene_locus related to this paper: human-DPP9

Title : DPP8\/9 inhibitors are universal activators of functional NLRP1 alleles - Gai_2019_Cell.Death.Dis_10_587
Author(s) : Gai K , Okondo MC , Rao SD , Chui AJ , Ball DP , Johnson DC , Bachovchin DA
Ref : Cell Death Dis , 10 :587 , 2019
PubMedID: 31383852
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : DPP8\/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages - de Vasconcelos_2019_Life.Sci.Alliance_2_
Author(s) : de Vasconcelos NM , Vliegen G , Goncalves A , De Hert E , Martin-Perez R , Van Opdenbosch N , Jallapally A , Geiss-Friedlander R , Lambeir AM , Augustyns K , Van der Veken P , De Meester I , Lamkanfi M
Ref : Life Sciences Alliance , 2 : , 2019
PubMedID: 30718379
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Expression and clinical role of the dipeptidyl peptidases DPP8 and DPP9 in ovarian carcinoma - Brunetti_2019_Virchows.Arch_474_177
Author(s) : Brunetti M , Holth A , Panagopoulos I , Staff AC , Micci F , Davidson B
Ref : Virchows Arch , 474 :177 , 2019
PubMedID: 30467600
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : DPP9's Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation - Griswold_2019_ACS.Chem.Biol_14_2424
Author(s) : Griswold AR , Ball DP , Bhattacharjee A , Chui AJ , Rao SD , Taabazuing CY , Bachovchin DA
Ref : ACS Chemical Biology , 14 :2424 , 2019
PubMedID: 31525884
Gene_locus related to this paper: human-DPP9

Title : Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity - Gall_2019_Sci.Rep_9_7292
Author(s) : Gall MG , Zhang HE , Lee Q , Jolly CJ , McCaughan GW , Cook A , Roediger B , Gorrell MD
Ref : Sci Rep , 9 :7292 , 2019
PubMedID: 31086209
Gene_locus related to this paper: human-DPP9

Title : DPP8\/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia - Johnson_2018_Nat.Med_24_1151
Author(s) : Johnson DC , Taabazuing CY , Okondo MC , Chui AJ , Rao SD , Brown FC , Reed C , Peguero E , de Stanchina E , Kentsis A , Bachovchin DA
Ref : Nat Med , 24 :1151 , 2018
PubMedID: 29967349
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Inhibition of Dpp8\/9 Activates the Nlrp1b Inflammasome - Okondo_2018_Cell.Chem.Biol_25_262
Author(s) : Okondo MC , Rao SD , Taabazuing CY , Chui AJ , Poplawski SE , Johnson DC , Bachovchin DA
Ref : Cell Chemical Biology , 25 :262 , 2018
PubMedID: 29396289
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding - Zhong_2018_J.Biol.Chem_293_18864
Author(s) : Zhong FL , Robinson K , Teo DET , Tan KY , Lim C , Harapas CR , Yu CH , Xie WH , Sobota RM , Au VB , Hopkins R , D'Osualdo A , Reed JC , Connolly JE , Masters SL , Reversade B
Ref : Journal of Biological Chemistry , 293 :18864 , 2018
PubMedID: 30291141
Gene_locus related to this paper: human-DPP9

Title : Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes - Koyani_2018_Front.Physiol_9_1622
Author(s) : Koyani CN , Trummer C , Shrestha N , Scheruebel S , Bourgeois B , Plastira I , Kickmaier S , Sourij H , Rainer PP , Madl T , Sattler W , Pelzmann B , Malle E , von Lewinski D
Ref : Front Physiol , 9 :1622 , 2018
PubMedID: 30487758
Gene_locus related to this paper: human-DPP9

Title : DPP9 enzymatic activity in hematopoietic cells is dispensable for mouse hematopoiesis - Kim_2018_Immunol.Lett_198_60
Author(s) : Kim M , von Muenchow L , Le Meur T , Kueng B , Gapp B , Weber D , Dietrich W , Kovarik J , Rolink AG , Ksiazek I
Ref : Immunol Lett , 198 :60 , 2018
PubMedID: 29709545
Gene_locus related to this paper: human-DPP9 , mouse-dpp9

Title : Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer - Ross_2018_Proc.Natl.Acad.Sci.U.S.A_115_E1437
Author(s) : Ross B , Krapp S , Augustin M , Kierfersauer R , Arciniega M , Geiss-Friedlander R , Huber R
Ref : Proc Natl Acad Sci U S A , 115 :E1437 , 2018
PubMedID: 29382749
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages - Taabazuing_2017_Cell.Chem.Biol_24_507
Author(s) : Taabazuing CY , Okondo MC , Bachovchin DA
Ref : Cell Chemical Biology , 24 :507 , 2017
PubMedID: 28392147
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis - Okondo_2017_Nat.Chem.Biol_13_46
Author(s) : Okondo MC , Johnson DC , Sridharan R , Go EB , Chui AJ , Wang MS , Poplawski SE , Wu W , Liu Y , Lai JH , Sanford DG , Arciprete MO , Golub TR , Bachovchin WW , Bachovchin DA
Ref : Nat Chemical Biology , 13 :46 , 2017
PubMedID: 27820798
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Expression, subcellular localisation, and possible roles of dipeptidyl peptidase 9 (DPP9) in murine macrophages - Zapletal_2017_Cell.Biochem.Funct_35_124
Author(s) : Zapletal E , Cupic B , Gabrilovac J
Ref : Cell Biochemistry & Function , 35 :124 , 2017
PubMedID: 28256001
Gene_locus related to this paper: human-DPP9

Title : Dipeptidyl peptidase 9 (DPP9) in human skin cells - Gabrilovac_2017_Immunobiology_222_327
Author(s) : Gabrilovac J , Cupic B , Zapletal E , Kraus O , Jakic-Razumovic J
Ref : Immunobiology , 222 :327 , 2017
PubMedID: 27682012
Gene_locus related to this paper: human-DPP9

Title : Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches - Wilson_2016_Biol.Chem_397_837
Author(s) : Wilson CH , Zhang HE , Gorrell MD , Abbott CA
Ref : Biol Chem , 397 :837 , 2016
PubMedID: 27410463
Gene_locus related to this paper: human-DPP9

Title : The SUMO1-E67 Interacting Loop Peptide Is an Allosteric Inhibitor of the Dipeptidyl Peptidases 8 and 9 - Pilla_2013_J.Biol.Chem_288_32787
Author(s) : Pilla E , Kilisch M , Lenz C , Urlaub H , Geiss-Friedlander R
Ref : Journal of Biological Chemistry , 288 :32787 , 2013
PubMedID: 24072711
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : A Novel SUMO1-specific Interacting Motif in Dipeptidyl Peptidase 9 (DPP9) That Is Important for Enzymatic Regulation - Pilla_2012_J.Biol.Chem_287_44320
Author(s) : Pilla E , Moller U , Sauer G , Mattiroli F , Melchior F , Geiss-Friedlander R
Ref : Journal of Biological Chemistry , 287 :44320 , 2012
PubMedID: 23152501
Gene_locus related to this paper: human-DPP9

Title : Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? - Van Goethem_2011_J.Med.Chem_54_5737
Author(s) : Van Goethem S , Matheeussen V , Joossens J , Lambeir AM , Chen X , De Meester I , Haemers A , Augustyns K , Van der Veken P
Ref : Journal of Medicinal Chemistry , 54 :5737 , 2011
PubMedID: 21711053
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9 - Tang_2011_FEBS.Lett_585_3409
Author(s) : Tang HK , Chen KC , Liou GG , Cheng SC , Chien CH , Tang HY , Huang LH , Chang HP , Chou CY , Chen X
Ref : FEBS Letters , 585 :3409 , 2011
PubMedID: 22001206
Gene_locus related to this paper: human-DPP4 , human-DPP9

Title : A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling - Yao_2011_Mol.Cancer.Res_9_948
Author(s) : Yao TW , Kim WS , Yu DM , Sharbeen G , McCaughan GW , Choi KY , Xia P , Gorrell MD
Ref : Mol Cancer Research , 9 :948 , 2011
PubMedID: 21622624
Gene_locus related to this paper: human-DPP9

Title : The in vivo expression of dipeptidyl peptidases 8 and 9 - Yu_2009_J.Histochem.Cytochem_57_1025
Author(s) : Yu DM , Ajami K , Gall MG , Park J , Lee CS , Evans KA , McLaughlin EA , Pitman MR , Abbott CA , McCaughan GW , Gorrell MD
Ref : Journal of Histochemistry & Cytochemistry , 57 :1025 , 2009
PubMedID: 19581630
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Biochemical properties and expression profile of human prolyl dipeptidase DPP9 - Tang_2009_Arch.Biochem.Biophys_485_120
Author(s) : Tang HK , Tang HY , Hsu SC , Chu YR , Chien CH , Shu CH , Chen X
Ref : Archives of Biochemistry & Biophysics , 485 :120 , 2009
PubMedID: 19268648
Gene_locus related to this paper: human-DPP9

Title : The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides - Geiss-Friedlander_2009_J.Biol.Chem_284_27211
Author(s) : Geiss-Friedlander R , Parmentier N , Moller U , Urlaub H , Van den Eynde BJ , Melchior F
Ref : Journal of Biological Chemistry , 284 :27211 , 2009
PubMedID: 19667070
Gene_locus related to this paper: human-DPP9

Title : DP8 and DP9 have extra-enzymatic roles in cell adhesion, migration and apoptosis -
Author(s) : Yu DM , Wang XM , Ajami K , McCaughan GW , Gorrell MD
Ref : Advances in Experimental Medicine & Biology , 575 :63 , 2006
PubMedID: 16700509
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis - Yu_2006_FEBS.J_273_2447
Author(s) : Yu DM , Wang XM , McCaughan GW , Gorrell MD
Ref : Febs J , 273 :2447 , 2006
PubMedID: 16704418
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV - Bjelke_2006_Biochem.J_396_391
Author(s) : Bjelke JR , Christensen J , Nielsen PF , Branner S , Kanstrup AB , Wagtmann N , Rasmussen HB
Ref : Biochemical Journal , 396 :391 , 2006
PubMedID: 16475979
Gene_locus related to this paper: human-DPP9

Title : Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases - Qi_2003_Biochem.J_373_179
Author(s) : Qi SY , Riviere PJ , Trojnar J , Junien JL , Akinsanya KO
Ref : Biochemical Journal , 373 :179 , 2003
PubMedID: 12662155
Gene_locus related to this paper: human-DPP8 , human-DPP9 , human-DPP10 , mouse-dpp9 , mouse-dpp10

Title : Structural requirements for catalysis, expression, and dimerization in the CD26\/DPIV gene family - Ajami_2003_Biochemistry_42_694
Author(s) : Ajami K , Abbott CA , Obradovic M , Gysbers V , Kahne T , McCaughan GW , Gorrell MD
Ref : Biochemistry , 42 :694 , 2003
PubMedID: 12534281
Gene_locus related to this paper: human-DPP8 , human-DPP9

Title : Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV - Olsen_2002_Gene_299_185
Author(s) : Olsen C , Wagtmann N
Ref : Gene , 299 :185 , 2002
PubMedID: 12459266
Gene_locus related to this paper: human-DPP9