9KPI

Name : Aromatic acetyl piperidine derivative DJ-89 as soluble epoxide hydrolase inhibitor

Revelation date : 16-Apr-2025

Family : Epoxide_hydrolase

Gene_locus : human-EPHX2

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Wang, H., Feng, Y., Du, X.Y.

Ligand : Inhibitor DJ-89 Ligand in structure: Ligplot

References (1)

Title : Discovery of Phenylacylpiperidine as Novel sEH Inhibitors through Scaffold Hopping of Natural Stilbene - Ding_2025_J.Med.Chem__
Author(s) : Ding J , Zhu MZ , Du XY , Liu SM , Wang H , Liu XZ , Xie WS , Ma HL , Feng Y , Zhu XH , Liang JH
Ref : Journal of Medicinal Chemistry , : , 2025
Abstract :
PubMedSearch : Ding_2025_J.Med.Chem__
PubMedID: 40227865
Gene_locus related to this paper: human-EPHX2

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 9KPI Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 9KPI Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 9KPI Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 9KPI 3D, interactive encyclopedia of proteins - PROTEOPEDIA server