9Q5Y
Name : Human prolyl endopeptidase (PREP) - complex with YX45
Revelation date : 21-Jan-2026
Family : S9N_PPCE_Peptidase_S9
Gene_locus : human-PREP
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Fucci, I.J.,Thakur, K.,Pandian, J.,Yoo, E.,Monteiro, D.C.F.
References (2)
| Title : Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition - Thakur_2026_J.Med.Chem__ |
| Author(s) : Thakur K , Fucci I , Pandian J , Suazo KF , Monteiro DCF , Yoo E |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Thakur_2026_J.Med.Chem__ |
| PubMedID: 41512187 |
| Gene_locus related to this paper: human-PREPL |
| Title : Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition - Thakur_2026_J.Med.Chem__ |
| Author(s) : Thakur K , Fucci I , Pandian J , Suazo KF , Monteiro DCF , Yoo E |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Thakur_2026_J.Med.Chem__ |
| PubMedID: 41512187 |
| Gene_locus related to this paper: human-PREPL |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 9Q5Y Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 9Q5Y Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 9Q5Y Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 9Q5Y 3D, interactive encyclopedia of proteins - PROTEOPEDIA server