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Structure Report for: 5T4E

Name|Human DPP4 in complex with a ligand 19a
Revelation date|05-Oct-2016
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 182 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Pissarnitski, D.A., Zhao, Z., Cole, D., Wu, W.L., Domalski, M., Clader, J.W., Scapin, G., Voigt, J., Soriano, A., Kelly, T., Powles, M.A., Yao, Z., Burnett, D.A.
Ligand|Inhibitor: 75L-5T4E Ligand in structure: Ligplot


    Title: Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors
    Pissarnitski DA, Zhao Z, Cole D, Wu WL, Domalski M, Clader JW, Scapin G, Voigt J, Soriano A and Burnett DA <3 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 24:5534, 2016 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum5T4E Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5T4E Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5T4E Structural Classification Of Protein - SCOP server
PROTEOPEDIA5t4e 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
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