| Title : Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors - Pissarnitski_2016_Bioorg.Med.Chem_24_5534 |
| Author(s) : Pissarnitski DA , Zhao Z , Cole D , Wu WL , Domalski M , Clader JW , Scapin G , Voigt J , Soriano A , Kelly T , Powles MA , Yao Z , Burnett DA |
| Ref : Bioorganic & Medicinal Chemistry , 24 :5534 , 2016 |
| Abstract : |
| PubMedSearch : Pissarnitski_2016_Bioorg.Med.Chem_24_5534 |
| PubMedID: 27670099 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity - Clader_2004_Bioorg.Med.Chem_12_319 |
| Author(s) : Clader JW , Billard W , Binch H, 3rd , Chen LY , Crosby G, Jr. , Duffy RA , Ford J , Kozlowski JA , Lachowicz JE , Li S , Liu C , McCombie SW , Vice S , Zhou G , Greenlee WJ |
| Ref : Bioorganic & Medicinal Chemistry , 12 :319 , 2004 |
| Abstract : |
| PubMedSearch : Clader_2004_Bioorg.Med.Chem_12_319 |
| PubMedID: 14723952 |
| Title : Isopropyl amide derivatives of potent and selective muscarinic M2 receptor antagonists - Palani_2004_Bioorg.Med.Chem.Lett_14_1791 |
| Author(s) : Palani A , Dugar S , Clader JW , Greenlee WJ , Ruperto V , Duffy RA , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1791 , 2004 |
| Abstract : |
| PubMedSearch : Palani_2004_Bioorg.Med.Chem.Lett_14_1791 |
| PubMedID: 15026073 |
| Title : Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution - Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| Author(s) : Boyle CD , Chackalamannil S , Clader JW , Greenlee WJ , Josien HB , Kaminski JJ , Kozlowski JA , McCombie SW , Nazareno DV , Tagat JR , Wang Y , Zhou G , Billard W , Binch H , Crosby G , Cohen-Williams M , Coffin VL , Cox KA , Grotz DE , Duffy RA , Ruperto V , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 11 :2311 , 2001 |
| Abstract : |
| PubMedSearch : Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| PubMedID: 11527721 |
| Title : Design and synthesis of piperidinyl piperidine analogues as potent and selective M2 muscarinic receptor antagonists - Wang_2000_Bioorg.Med.Chem.Lett_10_2247 |
| Author(s) : Wang Y , Chackalamannil S , Hu Z , Clader JW , Greenlee W , Billard W , Binch H , Crosby G , Ruperto V , Duffy RA , McQuade R , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 10 :2247 , 2000 |
| Abstract : |
| PubMedSearch : Wang_2000_Bioorg.Med.Chem.Lett_10_2247 |
| PubMedID: 11055330 |