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Structure Report for: 5YP2

Name|Crystal structure of dipeptidyl peptidase IV (DPP IV) with DPP4 inhibitor from Pseudoxanthomonas mexicana WO24
Revelation date|21-Feb-2018
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 182 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Roppongi, S., Suzuki, Y., Tateoka, C., Fuimoto, M., Morisawa, S., Iizuka, I., Nakamura, A., Honma, N., Shida, Y., Ogasawara, W., Tanaka, N., Sakamoto, Y., Nonaka, T.
Ligand|Inhibitor: 5YP2-8YC Ligand in structure: Ligplot


    Title: Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues
    Roppongi S, Suzuki Y, Tateoka C, Fujimoto M, Morisawa S, Iizuka I, Nakamura A, Honma N, Shida Y and Nonaka T <3 more author(s)>
    Ref: Sci Rep, 8:2714, 2018 : PubMed


    Title: Periplasmic form of dipeptidyl aminopeptidase IV from Pseudoxanthomonas mexicana WO24: purification, kinetic characterization, crystallization and X-ray crystallographic analysis
    Roppongi S, Tateoka C, Fujimoto M, Iizuka I, Morisawa S, Nakamura A, Honma N, Suzuki Y, Shida Y and Nonaka T <3 more author(s)>
    Ref: Acta Crystallographica F Struct Biol Commun, 73:601, 2017 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum5YP2 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP5YP2 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP5YP2 Structural Classification Of Protein - SCOP server
PROTEOPEDIA5yp2 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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