(R,S)-DMPM
(R,S)-DMPM substrate for synthesis of (R)-metalaxyl which displays fungicide activity
General
Type : Propionate
Chemical_Nomenclature : methyl 2-(2,6-dimethylanilino)propanoate
Canonical SMILES : CC1=C(C(=CC=C1)C)NC(C)C(=O)OC
InChI : InChI=1S\/C12H17NO2\/c1-8-6-5-7-9(2)11(8)13-10(3)12(14)15-4\/h5-7,10,13H,1-4H3
InChIKey : NEOYGRJJOGVQPO-UHFFFAOYSA-N
Other name(s) : N-2,6-xylyl methyl L-alaninate || SCHEMBL6264671 || ZINC3172333 || methyl N-(2,6-dimethylphenyl)-alaninate || N-(2,6-Dimethylphenyl) alanine methyl ester || Methyl 2-((2,6-dimethylphenyl)amino)propanoate || methyl 2-(2,6-dimethylanilino)propanoate || alpha-(2,6-dimethylanilino)-propionic acid methyl ester || Methyl (R, S)-2, 6-dimethylphenylaminopropionate || Methyl (R, S)-N-(2, 6-Dimethylphenyl) Alaninate
MW : 207.27
Formula : C12H17NO2
CAS_number :
PubChem : 11481178, 94555, 10921686
UniChem : NEOYGRJJOGVQPO-UHFFFAOYSA-N
-DMPM.gif)
Target
Structures : No structure
Families : Bacterial_lip_FamI.2, AHL-acylase
References (9)
| Title : A Novel Esterase from Burkholderia sp. YD106 Capable of Hydrolysis of Methyl (R, S)-N-(2, 6-Dimethylphenyl) Alaninate, and Its Mutation for Improving Enantioselectivity - Yang_2025_Appl.Biochem.Biotechnol__ |
| Author(s) : Yang R , Wu J , Zhang Y , Zhang Z |
| Ref : Appl Biochem Biotechnol , : , 2025 |
| Abstract : |
| PubMedSearch : Yang_2025_Appl.Biochem.Biotechnol__ |
| PubMedID: 40531301 |
| Title : A Novel Esterase from Burkholderia sp. YD106 Capable of Hydrolysis of Methyl (R, S)-N-(2, 6-Dimethylphenyl) Alaninate, and Its Mutation for Improving Enantioselectivity - Yang_2025_Appl.Biochem.Biotechnol__ |
| Author(s) : Yang R , Wu J , Zhang Y , Zhang Z |
| Ref : Appl Biochem Biotechnol , : , 2025 |
| Abstract : |
| PubMedSearch : Yang_2025_Appl.Biochem.Biotechnol__ |
| PubMedID: 40531301 |
| Title : A Novel Esterase from Burkholderia sp. YD106 Capable of Hydrolysis of Methyl (R, S)-N-(2, 6-Dimethylphenyl) Alaninate, and Its Mutation for Improving Enantioselectivity - Yang_2025_Appl.Biochem.Biotechnol__ |
| Author(s) : Yang R , Wu J , Zhang Y , Zhang Z |
| Ref : Appl Biochem Biotechnol , : , 2025 |
| Abstract : |
| PubMedSearch : Yang_2025_Appl.Biochem.Biotechnol__ |
| PubMedID: 40531301 |
| Title : A Novel esterase from Pseudochrobactrum asaccharolyticum WZZ003: Enzymatic properties toward model substrate and catalytic performance in chiral fungicide intermediate synthesis - Cheng_2018_Process.Biochem_69_92 |
| Author(s) : Cheng F , Zheng J , Wu G , Zhang Y , Wang Z |
| Ref : Process Biochemistry , 69 :92 , 2018 |
| Abstract : |
| PubMedSearch : Cheng_2018_Process.Biochem_69_92 |
| PubMedID: |
| Gene_locus related to this paper: 9hyph-a0a2r3sty9 |
| Title : A Novel esterase from Pseudochrobactrum asaccharolyticum WZZ003: Enzymatic properties toward model substrate and catalytic performance in chiral fungicide intermediate synthesis - Cheng_2018_Process.Biochem_69_92 |
| Author(s) : Cheng F , Zheng J , Wu G , Zhang Y , Wang Z |
| Ref : Process Biochemistry , 69 :92 , 2018 |
| Abstract : |
| PubMedSearch : Cheng_2018_Process.Biochem_69_92 |
| PubMedID: |
| Gene_locus related to this paper: 9hyph-a0a2r3sty9 |
| Title : A Novel esterase from Pseudochrobactrum asaccharolyticum WZZ003: Enzymatic properties toward model substrate and catalytic performance in chiral fungicide intermediate synthesis - Cheng_2018_Process.Biochem_69_92 |
| Author(s) : Cheng F , Zheng J , Wu G , Zhang Y , Wang Z |
| Ref : Process Biochemistry , 69 :92 , 2018 |
| Abstract : |
| PubMedSearch : Cheng_2018_Process.Biochem_69_92 |
| PubMedID: |
| Gene_locus related to this paper: 9hyph-a0a2r3sty9 |
| Title : Stereoselective lipases from Burkholderia sp., cloning and their application to preparation of methyl (R)-N-(2,6-dimethylphenyl)alaninate, a key intermediate for (R)-Metalaxyl - Park_2005_J.Biotechnol_120_174 |
| Author(s) : Park OJ , Lee SH |
| Ref : J Biotechnol , 120 :174 , 2005 |
| Abstract : |
| PubMedSearch : Park_2005_J.Biotechnol_120_174 |
| PubMedID: 16102866 |
| Gene_locus related to this paper: 9pseu-a0a0p0s9g4 , burce-lipaa |
| Title : Stereoselective lipases from Burkholderia sp., cloning and their application to preparation of methyl (R)-N-(2,6-dimethylphenyl)alaninate, a key intermediate for (R)-Metalaxyl - Park_2005_J.Biotechnol_120_174 |
| Author(s) : Park OJ , Lee SH |
| Ref : J Biotechnol , 120 :174 , 2005 |
| Abstract : |
| PubMedSearch : Park_2005_J.Biotechnol_120_174 |
| PubMedID: 16102866 |
| Gene_locus related to this paper: 9pseu-a0a0p0s9g4 , burce-lipaa |
| Title : Stereoselective lipases from Burkholderia sp., cloning and their application to preparation of methyl (R)-N-(2,6-dimethylphenyl)alaninate, a key intermediate for (R)-Metalaxyl - Park_2005_J.Biotechnol_120_174 |
| Author(s) : Park OJ , Lee SH |
| Ref : J Biotechnol , 120 :174 , 2005 |
| Abstract : |
| PubMedSearch : Park_2005_J.Biotechnol_120_174 |
| PubMedID: 16102866 |
| Gene_locus related to this paper: 9pseu-a0a0p0s9g4 , burce-lipaa |