7-STCFC
7-STCFC can be rapidly hydrolyzed by human pancreatic lipase to form 7-HTCFC, which triggers 254-fold NIR signal enhancement at 670 nm
General
Type : Fatty acid ester, Water-insoluble medium and long chain ester, Oleate, Fluorescent Probe, Near-Infrared fluorescent Probe, Coumarin
Chemical_Nomenclature :
Canonical SMILES : C1=C(C=C2C(=C1)C=C(C(O2)=O)C=CC3=C(C#N)C(OC3(C)C)=C(C#N)C#N)OC(CCCCCCCCCCCCCCCCC)=O
InChI : InChI=1S\/C39H47N3O5\/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-36(43)45-32-22-20-29-24-30(38(44)46-35(29)25-32)21-23-34-33(28-42)37(31(26-40)27-41)47-39(34,2)3\/h20-25H,4-19H2,1-3H3\/b23-21+
InChIKey : LYOXKOXNTWTMIN-XTQSDGFTSA-N
Other name(s) :
Target
Structures : No structure
Families : Pancreatic_lipase
References (1)
| Title : A rationally engineered specific near-infrared fluorogenic substrate of human pancreatic lipase for functional imaging and inhibitor screening - Hou_2023_Analyst__ |
| Author(s) : Hou FB , Zhang N , Hou XD , Liu W , Fan YF , Zhu GH , Wu Y , Sun MR , Zhao B , Ge GB , Wang P |
| Ref : Analyst , : , 2023 |
| Abstract : |
| PubMedSearch : Hou_2023_Analyst__ |
| PubMedID: 37092796 |