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Coumarin

Coumarin is derived from coumarou, the French word for the tonka bean. Some naturally occurring coumarin derivatives include umbelliferone (7-hydroxycoumarin), aesculetin (6,7-dihydroxycoumarin), herniarin (7-methoxycoumarin), psoralen and imperatorin
Substrate Main targeted enzyme families Type Structure
Epalrestat-RM-13 Not A\/B H target Pro-Drug Drug Fluorescent Probe Coumarin Chromen Thiazolidine Sulfur Compound
Epalrestat-RM-28 Not A\/B H target Pro-Drug Drug Fluorescent Probe Coumarin Chromen
7-HC-arachidonate Monoglyceridelipase_lysophospholip Fatty acid ester Fluorescent Probe Coumarin Chromen Cannabinoid-Receptor-ligand Arachidonate
7-hydroxycoumarinyl-gamma-linolenate Monoglyceridelipase_lysophospholip Fatty acid ester Fluorescent Probe Coumarin Chromen Cannabinoid-Receptor-ligand
mUPET1 Polyesterase-lipase-cutinase Tannase Coumarin Chromen Terephthalate Phthalate
mUPET2 Polyesterase-lipase-cutinase Tannase Coumarin Chromen Terephthalate Phthalate
mUPET3 Polyesterase-lipase-cutinase Tannase Coumarin Chromen Terephthalate Phthalate
CHC-CES1 Carb_B_Chordata Fluorescent Probe Coumarin
7-STCFC Pancreatic_lipase Fatty acid ester Water-insoluble medium and long chain ester Oleate Fluorescent Probe Near-Infrared fluorescent Probe Coumarin
Tert-pentyl-HTCF Carboxylesterase Carb_B_Chordata Fluorescent Probe Near-Infrared fluorescent Probe Coumarin
NCES Carb_B_Chordata Fluorescent Probe Near-Infrared fluorescent Probe Cyanide Coumarin
HCCA-Ac Carb_B_Chordata Coumarin Acetate Chromen
p-coumaryl-trisaccharide FAE-Bacterial-promiscuous BD-FAE Coumarin Hydroxycinnamic-ester Polysaccharide
Mca-RPPGFSAFK(Dnp)-OH Carboxypeptidase_S10 Peptide FRET-Peptide Fluorescent Probe Coumarin
Coumarin-3-carboxylic-acid FAE-Bacterial-promiscuous Natural Coumarin Chromen
DEPFMU Fluorescent Probe Organophosphate Flu-OP Coumarin Chromen
CSL174 AlphaBeta_hydrolase Peptide Fluorescent Probe Coumarin
Ethyl-coumarin-3-carboxylate FAE-Bacterial-promiscuous Coumarin Chromen
P-PMHC Acidic_Lipase Coumarin Palmitate Hexadecanoate
Z-Gly-Gly-Arg-AMC S9N_PREPL_Peptidase_S9 Benzyloxycarbonyl Peptide 7-amido-4-methylcoumarin Coumarin Chromen
Bz-Arg-AMC S9N_PREPL_Peptidase_S9 Peptide 7-amido-4-methylcoumarin Coumarin Benzamide Chromen
Z-Phe-Arg-AMC S9N_PREPL_Peptidase_S9 Benzyloxycarbonyl Peptide 7-amido-4-methylcoumarin Coumarin Chromen
Z-Arg-Arg-AMC S9N_PREPL_Peptidase_S9 Benzyloxycarbonyl Peptide 7-amido-4-methylcoumarin Coumarin Chromen
Boc-Gly-Arg-Arg-AMC S9N_PREPL_Peptidase_S9 Peptide 7-amido-4-methylcoumarin Coumarin tert-Butyl Chromen
GC242 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC240 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC486 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
Ala-Pro-AFC Prolylcarboxypeptidase DPP4N_Peptidase_S9 Peptide Coumarin Trifluoro Pyrrolidine Carboxamide Chromen
AHMMCE Monoglyceridelipase_lysophospholip ABHD6-Lip Cannabinoid-Receptor-ligand Fluorescent Probe Coumarin Chromen
DiFMU-acetate RsbQ-like Coumarin Fluorescent Probe DifMU derivative Acetate
DiFMU-butyrate Coumarin Chromen Fluorescent Probe DifMU derivative Butyrate
DiFMU-octanoate Lipase_3 Canar_LipB S9N_PREPL_Peptidase_S9 Coumarin Fluorescent Probe DifMU derivative Chromen
H-Pro-AMC Proline_iminopeptidase Peptide Coumarin Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
4-methylumbelliferyl-laurate Plant_carboxylesterase Dodecanoate Coumarin Laurate Chromen
4-methylumbelliferyl-palmitate Plant_carboxylesterase Fungal_carboxylesterase_lipase Acidic_Lipase BCHE Coumarin Chromen Palmitate Hexadecanoate
4-methylumbelliferyl-oleate Acidic_Lipase Pancreatic_lipase Fungal_carboxylesterase_lipase Coumarin Oleate Chromen
4-methylumbelliferyl-caprylate Bacterial_lip_FamI.5 Plant_carboxylesterase Plasmodium_subtelomeric_PST-A Tannase Coumarin Octanoate Chromen
4-methylumbelliferyl-heptanoate Thioesterase Plant_carboxylesterase A85-EsteraseD-FGH Coumarin Chromen
Gly-Pro-AMC DPP4N_Peptidase_S9 Coumarin Peptide Pyrrolidine Carboxamide 7-amido-4-methylcoumarin Chromen
4-Methylumbelliferyl-butyrate HNLyase_Bact Plant_carboxylesterase Lipase_2 Bacterial_lip_FamI.3 Coumarin Butyrate Chromen
4-methylumbelliferyl-acetate Carb_B_Chordata Esterase_phb A85-EsteraseD-FGH Acetyl-esterase_deacetylase Plant_carboxylesterase 6_AlphaBeta_hydrolase A85-Feruloyl-Esterase Coumarin Acetate Chromen
Z-Gly-Pro-AMC S9N_PPCE_Peptidase_S9 DPP4N_Peptidase_S9 Benzyloxycarbonyl Peptide Pyrrolidine 7-amido-4-methylcoumarin Coumarin Chromen
dMUP Carb_B_Arthropoda Organophosphate Coumarin Chromen
Methyl-DEUP Carb_B_Arthropoda Organophosphate Coumarin Chromen
DEUP Carb_B_Arthropoda Hormone-sensitive_lipase_like Arylacetamide_deacetylase Organophosphate Coumarin Chromen
3,4-Dihydrocoumarin Haloperoxidase Coumarin Chromen