Alpha-Angelica-lactone
Analogue of substrate could not be found in structure of lactonase (2XUA) but the product lavulinic acid was found. Alpha angelica lactone also used as acyl donor in transesterification/Acyltransferase reaction instead of hydroalase reaction by lipases
General
Type : Lactone, Butenolide, Analogue of substrate
Chemical_Nomenclature : 5-methyl-3H-furan-2-one
Canonical SMILES : CC1=CCC(=O)O1
InChI : InChI=1S\/C5H6O2\/c1-4-2-3-5(6)7-4\/h2H,3H2,1H3
InChIKey : QOTQFLOTGBBMEX-UHFFFAOYSA-N
Other name(s) : 4-hydroxy-3-pentenoic acid gamma-lactone || 4-hydroxy-3-pentenoic-acid-gamma-lactone || Alpha-Angelica lactone || Alpha-Angelicalactone || Alpha-Angelica-lactone || 5-Methyl-2(3H)-furanone || 5-Methylfuran-2(3H)-one || 2(3H)-FURANONE, 5-METHYL-
MW : 98.10
Formula : C5H6O2
CAS_number : 591-12-8
PubChem : 11559
UniChem : QOTQFLOTGBBMEX-UHFFFAOYSA-N
Target
Structures : No structure
Families : Carboxymethylbutenolide_lactonase, Canar_LipB
References (2)
| Title : From Waste to ValueDirect Utilization of alpha-Angelica Lactone as a Nonconventional Irreversible Acylating Agent in a Chromatography-Free Lipase-Catalyzed KR Approach toward sec-Alcohols - Poterala_2021_ACS.Sustain.Chem.Eng_9_10276 |
| Author(s) : Poterala M , Borowiecki P |
| Ref : ACS Sustain Chem Eng , 9 :10276 , 2021 |
| Abstract : |
| PubMedSearch : Poterala_2021_ACS.Sustain.Chem.Eng_9_10276 |
| PubMedID: |
| Gene_locus related to this paper: canar-LipB |
| Title : A product analog bound form of 3-oxoadipate-enol-lactonase (PcaD) reveals a multifunctional role for the divergent cap domain - Bains_2011_J.Mol.Biol_406_649 |
| Author(s) : Bains J , Kaufman L , Farnell B , Boulanger MJ |
| Ref : Journal of Molecular Biology , 406 :649 , 2011 |
| Abstract : |
| PubMedSearch : Bains_2011_J.Mol.Biol_406_649 |
| PubMedID: 21237173 |
| Gene_locus related to this paper: burxl-q13kt2 |