Carboxymethylbutenolide_lactonase

Relationship

Family: Carboxymethylbutenolide_lactonase

Block: X

Parent Family: Abhydrolase_6

Comment

In some instance 3-oxoadipate enol-lactonase is fused to 4-carboxymucolactone- decarboxylase, which acts on the same pathway but this enzyme belongs to CMD IPR003779 PF02627 and is not related to alpha/beta hydrolase see Eulberg et al. 1998, see Schlomann et al. 1994 fo a review on the pathway. For bacterial enzymes, this family corresponds to family V.2 of the classification of Arpigny and Jaeger 1999

Database

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (2)

Genes Proteins in Carboxymethylbutenolide_lactonase family (725)

Fragments of genes in Carboxymethylbutenolide_lactonase family (1)

Structures in Carboxymethylbutenolide_lactonase family (2)

Substrates in Carboxymethylbutenolide_lactonase family (2)

Inhibitors in Carboxymethylbutenolide_lactonase family (1)

References (6)

Title : A product analog bound form of 3-oxoadipate-enol-lactonase (PcaD) reveals a multifunctional role for the divergent cap domain - Bains_2011_J.Mol.Biol_406_649
Author(s) : Bains J , Kaufman L , Farnell B , Boulanger MJ
Ref : Journal of Molecular Biology , 406 :649 , 2011
PubMedID: 21237173
Gene_locus related to this paper: burxl-q13kt2

Title : Lipases for biotechnology - Jaeger_2002_Curr.Opin.Biotechnol_13_390
Author(s) : Jaeger KE , Eggert T
Ref : Curr Opin Biotechnol , 13 :390 , 2002
PubMedID: 12323363

Title : Bacterial lipolytic enzymes: classification and properties - Arpigny_1999_Biochem.J_343_177
Author(s) : Arpigny JL , Jaeger KE
Ref : Biochemical Journal , 343 :177 , 1999
PubMedID: 10493927

Title : Characterization of a protocatechuate catabolic gene cluster from Rhodococcus opacus 1CP: evidence for a merged enzyme with 4-carboxymuconolactone-decarboxylating and 3-oxoadipate enol-lactone-hydrolyzing activity - Eulberg_1998_J.Bacteriol_180_1072
Author(s) : Eulberg D , Lakner S , Golovleva LA , Schlomann M
Ref : Journal of Bacteriology , 180 :1072 , 1998
PubMedID: 9495744
Gene_locus related to this paper: rhoop-pcaL

Title : Evolution of chlorocatechol catabolic pathways. Conclusions to be drawn from comparisons of lactone hydrolases - Schlomann_1994_Biodegradation_5_301
Author(s) : Schlomann M
Ref : Biodegradation , 5 :301 , 1994
PubMedID: 7765840

Title : Acquisition of apparent DNA slippage structures during extensive evolutionary divergence of pcaD and catD genes encoding identical catalytic activities in Acinetobacter calcoaceticus - Hartnett_1994_Gene_142_23
Author(s) : Hartnett GB , Ornston LN
Ref : Gene , 142 :23 , 1994
PubMedID: 8181753
Gene_locus related to this paper: aciad-q8rlz8 , acica-elh1