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Lactone

Lactones are cyclic carboxylic esters, containing a 1-oxacycloalkan-2-one structure (C(=O)O). Lactones are formed by intramolecular esterification. Building block for many substrates of enzymes
Substrate Main targeted enzyme families Type Structure
2,4-D-SL RsbQ-like Strigolactone Debranone Strigolactone receptors ligand
SL-agonist-Cpd61 RsbQ-like Natural Strigolactone Debranone Strigolactone receptors ligand
Dehydrocostus-lactone RsbQ-like Natural Strigolactone Debranone Strigolactone receptors ligand
Benzyl-malolactonate Fungal-Bact_LIP Lactone Ring opening polymerization substrate
AR36 RsbQ-like Strigolactone Strigolactone receptors ligand
CISA-1 RsbQ-like Strigolactone Strigolactone receptors ligand
thia-3'-methyl-debranone-like RsbQ-like Strigolactone Debranone Strigolactone receptors ligand Organochlorine
4-oxo-MeCLA Strigolactone receptors ligand Plant hormone Non-canonical strigolactone
MeCLA Plant_carboxylesterase RsbQ-like Strigolactone receptors ligand Plant hormone Non-canonical strigolactone
Medicaol Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Lotuslactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Zeapyranolactone Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Zealactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Fabacyl-acetate RsbQ-like Strigolactone receptors ligand Canonical strigolactone
Didehydroorobanchol RsbQ-like Butenolide Strigolactone receptors ligand
Sorgomol Butenolide Strigolactone receptors ligand
Orobanchyl-acetate RsbQ-like Butenolide Strigolactone receptors ligand
Heliolactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Carlactonoic-acid RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Carlactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
10-Methyldodec-2-en-4-olide RsbQ-like Butenolide Strigolactone receptors ligand
Hexadecalactone Canar_LipB Lactone Ring opening polymerization substrate Hexadecanoate Palmitate
delta-octalactone Lactone Natural
delta-hexadecalactone Canar_LipB Lactone Natural Pheromone Hexadecanoate Palmitate
epsilon-caprolactone Canar_LipB Lactone Ring opening polymerization substrate
D-D-lactone Canar_LipB Lactone Ring opening polymerization substrate
Pentadecalactone Canar_LipB Lactone Ring opening polymerization substrate
Japonilure Carb_B_Arthropoda Odorant Pheromone Lactone
Buibuilactone Odorant Pheromone Lactone
GY0 Thiohydrolase Analogue of substrate Lactone Propionate
1,5-Seco-vibralactone Hormone-sensitive_lipase_like Natural Lactone
desmethyl-4-Br-Debranone Strigolactone Debranone Strigolactone receptors ligand
Probenecid-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronide
Mycophenolic-acid-acyl-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronoyl Benzofuran Glucuronide
desmethyl-Yoshimulactone-Green RsbQ-like Lactone Strigolactone receptors ligand desmethyl Strigolactone receptors ligand Benzoate Xanthene
Xilatone-Red RsbQ-like Derivative of Resorufin Strigolactone receptors ligand Fluorescent Probe Lactone Phenoxazin Oxazine
Yoshimulactone-Green RsbQ-like Plant_carboxylesterase Lactone Strigolactone receptors ligand Fluorescent Probe Benzoate Xanthene
7-carba-4BD RsbQ-like Strigolactone Debranone Butenolide Strigolactone receptors ligand
N-3-oxo-dodecanoyl-L-homoserine-lactone Lactone Dodecanoate Homoserine
C4-HSL AlphaBeta_hydrolase Lactone Homoserine
C6-HSL AHL-acylase 6_AlphaBeta_hydrolase Lactone Homoserine
C8-HSL 6_AlphaBeta_hydrolase Lactone Homoserine
Karrikin-4 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Karrikin-3 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Karrikin-2 RsbQ-like Plant hormone Karrikin Butenolide desmethyl Strigolactone receptors ligand Strigolactone receptors ligand Natural
Karrikin-1 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Cotylimide-VI RsbQ-like Cotylimide Strigolactone receptors ligand Benzenesulfonamide Sulfonamide Sulfur Compound
Cotylimide-IV RsbQ-like Cotylimide Strigolactone receptors ligand Sulfur Compound Phthalimido Indole Isoindole Morpholine Sulfonyl
Methyl-phenlactonoate-butenolide-3 RsbQ-like Methyl Phenlactonoate Strigolactone receptors ligand Butenolide
Methyl-phenlactonoate-butenolide-16 RsbQ-like Methyl Phenlactonoate Strigolactone receptors ligand Butenolide
Nijmegen-1 RsbQ-like Cotylimide Strigolactone receptors ligand Isoindole Butenolide Phthalimido
SAM690 RsbQ-like Strigolactone receptors ligand Piperazine
Sphynolactone-7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
H-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
carba-H-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
1'-carba-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
5-Deoxystrigol RsbQ-like Plant_carboxylesterase Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Orobanchol RsbQ-like Plant_carboxylesterase Plant hormone Strigolactone Strigolactone receptors ligand Natural
4-Deoxyorobanchol RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Sorgolactone RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Contalactone RsbQ-like Strigolactone Strigolactone receptors ligand
3'-Methyl-GR24 RsbQ-like Strigolactone Strigolactone receptors ligand Inden
desmethyl-GR24 RsbQ-like Strigolactone Strigolactone receptors ligand Inden
GC242 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC240 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC486 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GR24 RsbQ-like Fungal-D14-Strigolactone-R Plant_carboxylesterase Strigolactone Butenolide Strigolactone receptors ligand Inden
Strigol RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Dienelactone Dienelactone_hydrolase Lactone
Alpha-Angelica-lactone Carboxymethylbutenolide_lactonase Canar_LipB Lactone Butenolide Analogue of substrate
3-Oxoadipate-enol-lactone Carboxymethylbutenolide_lactonase Lactone Butenolide Adipate
Juvenile-hormone-II Epoxide_hydrolase Natural Lactone Epoxide
Juvenile-hormone-III Epoxide_hydrolase Juvenile_hormone_esterase Natural Lactone Epoxide
3-oxo-C12-HSL AHL-acylase Lactone Dodecanoate Homoserine
D-Pantolactone Aryl ester Lactone
L-Pantolactone Aryl ester Lactone
delta-Valerolactone Epoxide_hydrolase 6_AlphaBeta_hydrolase Lactone
gamma-Valerolactone Lactone
2,4-D-SL RsbQ-like Strigolactone Debranone Strigolactone receptors ligand
SL-agonist-Cpd61 RsbQ-like Natural Strigolactone Debranone Strigolactone receptors ligand
Dehydrocostus-lactone RsbQ-like Natural Strigolactone Debranone Strigolactone receptors ligand
Benzyl-malolactonate Fungal-Bact_LIP Lactone Ring opening polymerization substrate
AR36 RsbQ-like Strigolactone Strigolactone receptors ligand
CISA-1 RsbQ-like Strigolactone Strigolactone receptors ligand
thia-3'-methyl-debranone-like RsbQ-like Strigolactone Debranone Strigolactone receptors ligand Organochlorine
4-oxo-MeCLA Strigolactone receptors ligand Plant hormone Non-canonical strigolactone
MeCLA Plant_carboxylesterase RsbQ-like Strigolactone receptors ligand Plant hormone Non-canonical strigolactone
Medicaol Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Lotuslactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Zeapyranolactone Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Zealactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Fabacyl-acetate RsbQ-like Strigolactone receptors ligand Canonical strigolactone
Didehydroorobanchol RsbQ-like Butenolide Strigolactone receptors ligand
Sorgomol Butenolide Strigolactone receptors ligand
Orobanchyl-acetate RsbQ-like Butenolide Strigolactone receptors ligand
Heliolactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Carlactonoic-acid RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Carlactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
10-Methyldodec-2-en-4-olide RsbQ-like Butenolide Strigolactone receptors ligand
Hexadecalactone Canar_LipB Lactone Ring opening polymerization substrate Hexadecanoate Palmitate
delta-octalactone Lactone Natural
delta-hexadecalactone Canar_LipB Lactone Natural Pheromone Hexadecanoate Palmitate
epsilon-caprolactone Canar_LipB Lactone Ring opening polymerization substrate
D-D-lactone Canar_LipB Lactone Ring opening polymerization substrate
Pentadecalactone Canar_LipB Lactone Ring opening polymerization substrate
Japonilure Carb_B_Arthropoda Odorant Pheromone Lactone
Buibuilactone Odorant Pheromone Lactone
GY0 Thiohydrolase Analogue of substrate Lactone Propionate
1,5-Seco-vibralactone Hormone-sensitive_lipase_like Natural Lactone
desmethyl-4-Br-Debranone Strigolactone Debranone Strigolactone receptors ligand
Probenecid-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronide
Mycophenolic-acid-acyl-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronoyl Benzofuran Glucuronide
desmethyl-Yoshimulactone-Green RsbQ-like Lactone Strigolactone receptors ligand desmethyl Strigolactone receptors ligand Benzoate Xanthene
Xilatone-Red RsbQ-like Derivative of Resorufin Strigolactone receptors ligand Fluorescent Probe Lactone Phenoxazin Oxazine
Yoshimulactone-Green RsbQ-like Plant_carboxylesterase Lactone Strigolactone receptors ligand Fluorescent Probe Benzoate Xanthene
7-carba-4BD RsbQ-like Strigolactone Debranone Butenolide Strigolactone receptors ligand
N-3-oxo-dodecanoyl-L-homoserine-lactone Lactone Dodecanoate Homoserine
C4-HSL AlphaBeta_hydrolase Lactone Homoserine
C6-HSL AHL-acylase 6_AlphaBeta_hydrolase Lactone Homoserine
C8-HSL 6_AlphaBeta_hydrolase Lactone Homoserine
Karrikin-4 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Karrikin-3 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Karrikin-2 RsbQ-like Plant hormone Karrikin Butenolide desmethyl Strigolactone receptors ligand Strigolactone receptors ligand Natural
Karrikin-1 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Cotylimide-VI RsbQ-like Cotylimide Strigolactone receptors ligand Benzenesulfonamide Sulfonamide Sulfur Compound
Cotylimide-IV RsbQ-like Cotylimide Strigolactone receptors ligand Sulfur Compound Phthalimido Indole Isoindole Morpholine Sulfonyl
Methyl-phenlactonoate-butenolide-3 RsbQ-like Methyl Phenlactonoate Strigolactone receptors ligand Butenolide
Methyl-phenlactonoate-butenolide-16 RsbQ-like Methyl Phenlactonoate Strigolactone receptors ligand Butenolide
Nijmegen-1 RsbQ-like Cotylimide Strigolactone receptors ligand Isoindole Butenolide Phthalimido
SAM690 RsbQ-like Strigolactone receptors ligand Piperazine
Sphynolactone-7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
H-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
carba-H-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
1'-carba-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
5-Deoxystrigol RsbQ-like Plant_carboxylesterase Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Orobanchol RsbQ-like Plant_carboxylesterase Plant hormone Strigolactone Strigolactone receptors ligand Natural
4-Deoxyorobanchol RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Sorgolactone RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Contalactone RsbQ-like Strigolactone Strigolactone receptors ligand
3'-Methyl-GR24 RsbQ-like Strigolactone Strigolactone receptors ligand Inden
desmethyl-GR24 RsbQ-like Strigolactone Strigolactone receptors ligand Inden
GC242 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC240 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC486 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GR24 RsbQ-like Fungal-D14-Strigolactone-R Plant_carboxylesterase Strigolactone Butenolide Strigolactone receptors ligand Inden
Strigol RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Dienelactone Dienelactone_hydrolase Lactone
Alpha-Angelica-lactone Carboxymethylbutenolide_lactonase Canar_LipB Lactone Butenolide Analogue of substrate
3-Oxoadipate-enol-lactone Carboxymethylbutenolide_lactonase Lactone Butenolide Adipate
Juvenile-hormone-II Epoxide_hydrolase Natural Lactone Epoxide
Juvenile-hormone-III Epoxide_hydrolase Juvenile_hormone_esterase Natural Lactone Epoxide
3-oxo-C12-HSL AHL-acylase Lactone Dodecanoate Homoserine
D-Pantolactone Aryl ester Lactone
L-Pantolactone Aryl ester Lactone
delta-Valerolactone Epoxide_hydrolase 6_AlphaBeta_hydrolase Lactone
gamma-Valerolactone Lactone
2,4-D-SL RsbQ-like Strigolactone Debranone Strigolactone receptors ligand
SL-agonist-Cpd61 RsbQ-like Natural Strigolactone Debranone Strigolactone receptors ligand
Dehydrocostus-lactone RsbQ-like Natural Strigolactone Debranone Strigolactone receptors ligand
Benzyl-malolactonate Fungal-Bact_LIP Lactone Ring opening polymerization substrate
AR36 RsbQ-like Strigolactone Strigolactone receptors ligand
CISA-1 RsbQ-like Strigolactone Strigolactone receptors ligand
thia-3'-methyl-debranone-like RsbQ-like Strigolactone Debranone Strigolactone receptors ligand Organochlorine
4-oxo-MeCLA Strigolactone receptors ligand Plant hormone Non-canonical strigolactone
MeCLA Plant_carboxylesterase RsbQ-like Strigolactone receptors ligand Plant hormone Non-canonical strigolactone
Medicaol Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Lotuslactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Zeapyranolactone Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Zealactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Fabacyl-acetate RsbQ-like Strigolactone receptors ligand Canonical strigolactone
Didehydroorobanchol RsbQ-like Butenolide Strigolactone receptors ligand
Sorgomol Butenolide Strigolactone receptors ligand
Orobanchyl-acetate RsbQ-like Butenolide Strigolactone receptors ligand
Heliolactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Carlactonoic-acid RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
Carlactone RsbQ-like Butenolide Strigolactone receptors ligand Non-canonical strigolactone
10-Methyldodec-2-en-4-olide RsbQ-like Butenolide Strigolactone receptors ligand
Hexadecalactone Canar_LipB Lactone Ring opening polymerization substrate Hexadecanoate Palmitate
delta-octalactone Lactone Natural
delta-hexadecalactone Canar_LipB Lactone Natural Pheromone Hexadecanoate Palmitate
epsilon-caprolactone Canar_LipB Lactone Ring opening polymerization substrate
D-D-lactone Canar_LipB Lactone Ring opening polymerization substrate
Pentadecalactone Canar_LipB Lactone Ring opening polymerization substrate
Japonilure Carb_B_Arthropoda Odorant Pheromone Lactone
Buibuilactone Odorant Pheromone Lactone
GY0 Thiohydrolase Analogue of substrate Lactone Propionate
1,5-Seco-vibralactone Hormone-sensitive_lipase_like Natural Lactone
desmethyl-4-Br-Debranone Strigolactone Debranone Strigolactone receptors ligand
Probenecid-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronide
Mycophenolic-acid-acyl-glucuronide ABHD10 Lactone Drug Not AlphaBeta Hydrolase target Glucuronoyl Benzofuran Glucuronide
desmethyl-Yoshimulactone-Green RsbQ-like Lactone Strigolactone receptors ligand desmethyl Strigolactone receptors ligand Benzoate Xanthene
Xilatone-Red RsbQ-like Derivative of Resorufin Strigolactone receptors ligand Fluorescent Probe Lactone Phenoxazin Oxazine
Yoshimulactone-Green RsbQ-like Plant_carboxylesterase Lactone Strigolactone receptors ligand Fluorescent Probe Benzoate Xanthene
7-carba-4BD RsbQ-like Strigolactone Debranone Butenolide Strigolactone receptors ligand
N-3-oxo-dodecanoyl-L-homoserine-lactone Lactone Dodecanoate Homoserine
C4-HSL AlphaBeta_hydrolase Lactone Homoserine
C6-HSL AHL-acylase 6_AlphaBeta_hydrolase Lactone Homoserine
C8-HSL 6_AlphaBeta_hydrolase Lactone Homoserine
Karrikin-4 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Karrikin-3 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Karrikin-2 RsbQ-like Plant hormone Karrikin Butenolide desmethyl Strigolactone receptors ligand Strigolactone receptors ligand Natural
Karrikin-1 RsbQ-like Plant hormone Karrikin Butenolide Natural Strigolactone receptors ligand
Cotylimide-VI RsbQ-like Cotylimide Strigolactone receptors ligand Benzenesulfonamide Sulfonamide Sulfur Compound
Cotylimide-IV RsbQ-like Cotylimide Strigolactone receptors ligand Sulfur Compound Phthalimido Indole Isoindole Morpholine Sulfonyl
Methyl-phenlactonoate-butenolide-3 RsbQ-like Methyl Phenlactonoate Strigolactone receptors ligand Butenolide
Methyl-phenlactonoate-butenolide-16 RsbQ-like Methyl Phenlactonoate Strigolactone receptors ligand Butenolide
Nijmegen-1 RsbQ-like Cotylimide Strigolactone receptors ligand Isoindole Butenolide Phthalimido
SAM690 RsbQ-like Strigolactone receptors ligand Piperazine
Sphynolactone-7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
H-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
carba-H-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
1'-carba-SPL7 RsbQ-like Strigolactone receptors ligand Piperazine Strigolactone
5-Deoxystrigol RsbQ-like Plant_carboxylesterase Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Orobanchol RsbQ-like Plant_carboxylesterase Plant hormone Strigolactone Strigolactone receptors ligand Natural
4-Deoxyorobanchol RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Sorgolactone RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Contalactone RsbQ-like Strigolactone Strigolactone receptors ligand
3'-Methyl-GR24 RsbQ-like Strigolactone Strigolactone receptors ligand Inden
desmethyl-GR24 RsbQ-like Strigolactone Strigolactone receptors ligand Inden
GC242 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC240 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GC486 RsbQ-like Strigolactone receptors ligand Fluorescent Probe Coumarin DifMU derivative Chromen
GR24 RsbQ-like Fungal-D14-Strigolactone-R Plant_carboxylesterase Strigolactone Butenolide Strigolactone receptors ligand Inden
Strigol RsbQ-like Plant hormone Strigolactone Strigolactone receptors ligand Natural Inden
Dienelactone Dienelactone_hydrolase Lactone
Alpha-Angelica-lactone Carboxymethylbutenolide_lactonase Canar_LipB Lactone Butenolide Analogue of substrate
3-Oxoadipate-enol-lactone Carboxymethylbutenolide_lactonase Lactone Butenolide Adipate
Juvenile-hormone-II Epoxide_hydrolase Natural Lactone Epoxide
Juvenile-hormone-III Epoxide_hydrolase Juvenile_hormone_esterase Natural Lactone Epoxide
3-oxo-C12-HSL AHL-acylase Lactone Dodecanoate Homoserine
D-Pantolactone Aryl ester Lactone
L-Pantolactone Aryl ester Lactone
delta-Valerolactone Epoxide_hydrolase 6_AlphaBeta_hydrolase Lactone
gamma-Valerolactone Lactone