BrefeldinA

General

Type : Natural, Antibiotic, Macrocycle, Toxin

Chemical_Nomenclature : (1S,2E,7S,10E,12R,13R,15S)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one

Canonical SMILES : CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O

InChI : InChI=1S\/C16H24O4\/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11\/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3\/b6-4+,8-7+\/t11-,12+,13-,14+,15+\/m0\/s1

InChIKey : KQNZDYYTLMIZCT-KQPMLPITSA-N

Other name(s) : Brefeldin A  ||  Ascotoxin  ||  Cyanein  ||  Decumbin  ||  Bredfeldin A  ||  Synergisidin  ||  gamma,4-Dihydroxy-2-[6-hydroxy-1heptenyl]-4-cyclopentanecrotonic acid lambda lactone


MW : 280.4

Formula : C16H24O4

CAS_number : 20350-15-6

PubChem : 5287620

UniChem : KQNZDYYTLMIZCT-KQPMLPITSA-N

Wikipedia : Brefeldin_A

Target

Structures : No structure

Families : Hormone-sensitive_lipase_like

References (1)

Title : Molecular characterization and cloning of an esterase which inactivates the macrolide toxin brefeldin A - Kneusel_1994_J.Biol.Chem_269_3449
Author(s) : Kneusel RE , Schiltz E , Matern U
Ref : Journal of Biological Chemistry , 269 :3449 , 1994
Abstract :
PubMedSearch : Kneusel_1994_J.Biol.Chem_269_3449
PubMedID: 8106385
Gene_locus related to this paper: bacsu-brefe