CHEMBL1784957

General

Type : Drug, Pro-Drug, Carbamate, Derivative of Rivastigmine

Chemical_Nomenclature : [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-[(2S)-1-phenylpropan-2-yl]carbamate

Canonical SMILES : CC(CC1=CC=CC=C1)NC(=O)OC2=CC=CC(=C2)C(C)N(C)C

InChI : InChI=1S\/C20H26N2O2\/c1-15(13-17-9-6-5-7-10-17)21-20(23)24-19-12-8-11-18(14-19)16(2)22(3)4\/h5-12,14-16H,13H2,1-4H3,(H,21,23)\/t15-,16-\/m0\/s1

InChIKey : HKJROXHSAHRDAO-HOTGVXAUSA-N

Other name(s) : CHEMBL1784957  ||  SCHEMBL7897597  ||  CHEMBL1789758  ||  BDBM50345811  ||  3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpropan-2-ylcarbamate hydrochloride


MW : 326.4

Formula : C20H26N2O2

CAS_number :

PubChem : 25205011

UniChem : HKJROXHSAHRDAO-HOTGVXAUSA-N

Target

Families : ACHE

References (1)

Title : Novel carbamate cholinesterase inhibitors that release biologically active amines following enzyme inhibition - Verheijen_2009_Bioorg.Med.Chem.Lett_19_3243
Author(s) : Verheijen JC , Wiig KA , Du S , Connors SL , Martin AN , Ferreira JP , Slepnev VI , Kochendorfer U
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :3243 , 2009
Abstract :
PubMedSearch : Verheijen_2009_Bioorg.Med.Chem.Lett_19_3243
PubMedID: 19423342