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Drug

Compounds that are used or were used or marketed as medication. A chemical substance used to treat, cure, prevent, or diagnose a disease
Substrate Main targeted enzyme familyes Type Structure
Unecritinib Not A\/B H target Pro-Drug Drug Piperidine Pyrazole Pyridine
Ramipril Carb_B_Chordata Not A\/B H target Pro-Drug Drug
NT-0796 Carboxylesterase Carb_B_Chordata Not A\/B H target Pro-Drug Drug Indacen Pyrimidine
Candesartan-cilexetil Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-receptor blocker
Fosinopril Plasmodium_subtelomeric_PST-A Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor Organophosphate
Fenofibrate Carb_B_Chordata Pro-Drug Drug Propionate
Sirpiglenastat Carb_B_Chordata Pro-Drug Drug Peptide
QA-Cbl BCHE Pro-Drug Drug Choline ester Trimethylammonium
Anordrin Carb_B_Chordata Pro-Drug Drug Propionate
Phospho-Ibuprofen Carb_B_Chordata phospho-NSAID Drug Pro-Drug
Rufinamide Carb_B_Chordata Drug Not A\/B H target Carboxamide Triazol
Dimethyl-fumarate Carb_B_Chordata Drug Pro-Drug Not A\/B H target
Beclomethasone-dipropionate Arylacetamide_deacetylase Drug Pro-Drug Not A\/B H target Steroid Propionate Phenanthrene
Esmolol Carb_B_Chordata LYsophospholipase_carboxylesterase Not A\/B H target Drug Propionate
S-bromobenzylglutathione-dicyclopentyl-ester Carb_B_Chordata Not A\/B H target Pro-Drug Drug Sulfur Compound Peptide
Diltiazem Carb_B_Chordata Not A\/B H target Drug Calcium Channel Antagonist Azepine Benzothiazepine
ADP-ribose Plant_lipase_EDS1-like Aminopurin Not A\/B H target Drug
Remimazolam Carb_B_Chordata Benzodiazepin Not A\/B H target Drug Propionate Azepine
MGS0274 Carb_B_Chordata Not A\/B H target Pro-Drug Drug
Tenofovir-alafenamide Carboxypeptidase_S10 Carb_B_Chordata Drug Pro-Drug Aminopurin Propionate
Mirabegron BCHE Drug Not A\/B H target Adrenergic-Receptor-ligand Thiazolidine Sulfur Compound
Ethyl-Zaltoprofen Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Not A\/B H target Drug Pro-Drug Propionate Alkyl ester
Ethyl-Carprofen Hormone-sensitive_lipase_like Not A\/B H target Drug Pro-Drug Carbazol Propionate Alkyl ester
Ethyl-Flurbiprofen Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Canar_LipB Not A\/B H target Drug Pro-Drug Propionate Alkyl ester
Imidapril Carb_B_Chordata Pro-Drug Drug Not A\/B H target Imidazole
Indiplon Arylacetamide_deacetylase Pro-Drug Drug Not A\/B H target Sulfur Compound Pyrimidine Pyrazole
Rifapentine Arylacetamide_deacetylase Pro-Drug Drug Not A\/B H target Piperazine Antibiotic
Rifabutin Arylacetamide_deacetylase Pro-Drug Drug Not A\/B H target Piperidine Antibiotic
Baloxavir-marboxil Arylacetamide_deacetylase Pro-Drug Drug Not A\/B H target Sulfur Compound
Abiraterone-acetate Arylacetamide_deacetylase Pro-Drug Drug Pyridine Not A\/B H target Phenanthrene
Ketoconazole Arylacetamide_deacetylase Pro-Drug Drug Not A\/B H target Piperazine Imidazole Dioxolane
Flupirtine Carb_B_Chordata Pro-Drug Drug Not A\/B H target Carbamate
Acebutolol Carb_B_Chordata Pro-Drug Drug Not A\/B H target
Mycophenolate-mofetil Carb_B_Chordata Pro-Drug Drug Not A\/B H target Morpholine Benzofuran
Nintedanib Carb_B_Chordata Pro-Drug Drug Not A\/B H target Piperazine
Vixotrigine Carb_B_Chordata Pro-Drug Drug Not A\/B H target Pyrrolidine Carboxamide
Clofibrate Carb_B_Chordata Pro-Drug Drug Not A\/B H target Propionate
Bemnifosbuvir Carboxypeptidase_S10 Carb_B_Chordata Pro-Drug Drug Not A\/B H target Propionate Purine
Remdesivir Carb_B_Chordata Carboxypeptidase_S10 Pro-Drug Drug Not A\/B H target Propionate Triazine
Molnupiravir Carb_B_Chordata BCHE Pro-Drug Drug Not A\/B H target Propionate Nucleoside
Idalopirdine-rivastigmine BCHE Drug Pro-Drug Indole Carbamate Derivative of Rivastigmine Multitarget 5-HT-receptor-ligand
CHEMBL1784957 ACHE Drug Pro-Drug Carbamate Derivative of Rivastigmine
CurDD BCHE CMBL Carb_B_Chordata Drug Pro-Drug Natural_modified
Rifampicin Arylacetamide_deacetylase Drug Not A\/B H target Acetate Natural Antibiotic
Prasugrel Carb_B_Chordata Arylacetamide_deacetylase Drug Not A\/B H target Acetate Cyclopropane
Eslicarbazepine-acetate Carb_B_Chordata Arylacetamide_deacetylase Drug Pro-Drug Benzazepin Carbamate Acetate Carboxamide Azepine
Trandolapril Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Probenecid-glucuronide ABHD10 Lactone Drug Not A\/B H target Glucuronide
Mycophenolic-acid-acyl-glucuronide ABHD10 Lactone Drug Not A\/B H target Glucuronoyl Benzofuran Glucuronide
Simvastatin Carb_B_Chordata Drug Not A\/B H target Naphthalen
Selexipag Carb_B_Chordata Sulfonyl Sulfur Compound Not A\/B H target Pro-Drug Drug
Ciclesonide Carb_B_Chordata BCHE Not A\/B H target Pro-Drug Butyrate Drug
Clevidipine Not A\/B H target Pro-Drug Butyrate Drug
Iomazenil Carb_B_Chordata Benzodiazepin Not A\/B H target Drug Azepine
Vicagrel Arylacetamide_deacetylase Carb_B_Chordata Not A\/B H target Drug Pyridine Acetate
2-oxo-clopidogrel Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyridine Acetate
Benzoylecgonine BCHE Cocaine_esterase Drug Not A\/B H target Alkaloid Azabicyclo
Dipivefrin Carb_B_Chordata ACHE BCHE Drug Not A\/B H target Pro-Drug Propionate
CHR-2863 Carb_B_Chordata Drug
Homatropine Carb_B_Chordata A85-Mycolyl-transferase Not A\/B H target Drug Azabicyclo
W22-methyl-ester Bacterial_esterase Canar_LipB Benzodiazepin Not A\/B H target Drug Pro-Drug Azepine
Enalapril Carb_B_Chordata Not A\/B H target Drug Pro-Drug Pyrrolidine Angiotensin-converting enzyme inhibitor
Quinapril Carb_B_Chordata Isoquinoline Not A\/B H target Drug Pro-Drug Angiotensin-converting enzyme inhibitor
Sacubitril Carb_B_Chordata Pro-Drug Not A\/B H target Drug Oxobutanoate
Dabigatran-etexilate Carb_B_Chordata Pro-Drug Not A\/B H target Drug Pyridine Propionate Benzimidazole
Clopidogrel Carb_B_Chordata Not A\/B H target Drug Pyridine
Temocapril Carb_B_Chordata Not A\/B H target Pro-Drug Drug Angiotensin-converting enzyme inhibitor Azepine
Methylphenidate Carb_B_Chordata Piperidine Not A\/B H target Drug
Oseltamivir Carb_B_Chordata BCHE Pro-Drug Drug Not A\/B H target
DTS-108 Carboxylesterase Carb_B_Chordata Drug Not A\/B H target Peptide
Valgancyclovir Valacyclovir-hydrolase Purine Drug Not A\/B H target
Valacyclovir Valacyclovir-hydrolase Purine Drug Not A\/B H target Nucleoside
Remifentanil Carboxylesterase Carb_B_Chordata Drug Not A\/B H target Opioid analgesic
Atropine BCHE AlphaBeta_hydrolase Not A\/B H target Muscarinic antagonist Drug Alkaloid Natural Azabicyclo Propionate
Carbachol ACHE Drug Not A\/B H target Carbamate Trimethylammonium Choline ester Analogue of substrate
NPC Carb_B_Bacteria Carbamate Drug Derivative of Irinotecan Not A\/B H target Piperidine
Meperidine BCHE Carboxylesterase Carb_B_Chordata Piperidine Opioid analgesic Drug Not A\/B H target
Mivacurium BCHE Neuromuscular Nondepolarizing Agents Drug Isoquinoline Bisquaternary Not A\/B H target
Permethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria pyrethroid Insecticide Drug Not A\/B H target Phenoxyphenyl Cyclopropyl
Irinotecan Carb_B_Chordata BCHE Carb_B_Bacteria Carbamate Drug Derivative of Irinotecan
Isosorbide-2-aspirinate BCHE Isosorbide Salicylic Acetate Benzoate Pro-Drug Drug
Isosorbide-2,5-diaspirinate BCHE Isosorbide Salicylic Acetate Benzoate Pro-Drug Drug
Nitroaspirin BCHE Salicylic Pro-Drug
Oxybuprocaine BCHE Drug Local anesthetic Not A\/B H target
Isosorbide-2-aspirinate-5-mononitrate BCHE Isosorbide Salicylic Pro-Drug
Isosorbide-2-aspirinate-5-salicylate BCHE Carb_B_Chordata Isosorbide Salicylic Acetate Benzoate Pro-Drug
Aspirin BCHE Carb_B_Chordata Salicylic Acetate Benzoate Drug
Bambuterol BCHE Pro-Drug Drug Carbamate tert-Butyl Adrenergic-Receptor-ligand
N-Methylnaloxonium Carb_B_Chordata Drug Isoquinoline
Cocaine BCHE Carb_B_Chordata Cocaine_esterase Natural Drug Alkaloid Benzoate Azabicyclo
6-monoacetylmorphine BCHE Natural Drug Isoquinoline Alkaloid
Heroin BCHE Carb_B_Chordata Natural Drug Isoquinoline Alkaloid
Methylprednisolone-acetate BCHE Acetate Steroid Phenanthrene Drug
Naproxen-Ethyl-Ester Canar_LipB 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen prodrug Pro-Drug Drug Naphthalen Propionate
Naproxen 6_AlphaBeta_hydrolase Canar_LipB Lipase_3 Hormone-sensitive_lipase_like Drug Naphthalen
Naproxen-Methyl-Ester 6_AlphaBeta_hydrolase Hormone-sensitive_lipase_like Profen prodrug Pro-Drug Drug Naphthalen Propionate
Ibuprofen-Ethyl-Ester Hormone-sensitive_lipase_like Profen prodrug Pro-Drug Drug Propionate
Ketoprofen-Glycerol-Ester Canar_LipB Profen prodrug Pro-Drug Drug Propionate
Ketoprofen-Vinyl-Ester Canar_LipB Profen prodrug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Butyl-Ester Canar_LipB Profen prodrug Pro-Drug Drug Aryl ester Propionate
Ketoprofen-Ethyl-Ester CarbLipBact_1 Hormone-sensitive_lipase_like Bacterial_lip_FamI.3 Lipase_2 Canar_LipB Profen prodrug Pro-Drug Drug Alkyl ester Propionate
Procaine BCHE Carb_B_Chordata Local anesthetic Drug Not A\/B H target
Lidocaine Carboxylesterase Carb_B_Chordata Local anesthetic Drug Not A\/B H target
Capecitabine Carboxylesterase Carb_B_Chordata Drug Carbamate Pyrimidine Pro-Drug