Chloramphenicol-3-acetate
General
Type : Antibiotic, Acetate, pNP, Organochlorine
Chemical_Nomenclature : [(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] acetate
Canonical SMILES : CC(=O)OC[C@H]([C@@H](C1=CC=C(C=C1)[N+](=O)[O-])O)NC(=O)C(Cl)Cl
InChI : InChI=1S\/C13H14Cl2N2O6\/c1-7(18)23-6-10(16-13(20)12(14)15)11(19)8-2-4-9(5-3-8)17(21)22\/h2-5,10-12,19H,6H2,1H3,(H,16,20)\/t10-,11-\/m1\/s1
InChIKey : VVOIFRARHIZCJD-GHMZBOCLSA-N
Other name(s) : Chloramphenicol 3-acetate || 3-Acetylchloramphenicol || 3'-O-acetylchloramphenicol || (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl acetate || CHEBI:16730 || RefChem:926523 || SCHEMBL4744337 || CHEMBL4177469
MW : 365.16
Formula : C13H14Cl2N2O6
CAS_number : 10318-16-8
PubChem : 83940
UniChem : VVOIFRARHIZCJD-GHMZBOCLSA-N
Target
Structures : No structure
Families : Hormone-sensitive_lipase_like
References (2)
| Title : Chloramphenicol Derivatives with Antibacterial Activity Identified by Functional Metagenomics - Nasrin_2018_J.Nat.Prod_81_1321 |
| Author(s) : Nasrin S , Ganji S , Kakirde KS , Jacob MR , Wang M , Ravu RR , Cobine PA , Khan IA , Wu CC , Mead DA , Li XC , Liles MR |
| Ref : Journal of Natural Products , 81 :1321 , 2018 |
| Abstract : |
| PubMedSearch : Nasrin_2018_J.Nat.Prod_81_1321 |
| PubMedID: 29897754 |
| Title : Characterization of two metagenome-derived esterases that reactivate chloramphenicol by counteracting chloramphenicol acetyltransferase - Tao_2011_J.Microbiol.Biotechnol_21_1203 |
| Author(s) : Tao W , Lee MH , Yoon MY , Kim JC , Malhotra S , Wu J , Hwang EC , Lee SW |
| Ref : J Microbiol Biotechnol , 21 :1203 , 2011 |
| Abstract : |
| PubMedSearch : Tao_2011_J.Microbiol.Biotechnol_21_1203 |
| PubMedID: 22210605 |
| Gene_locus related to this paper: 9bact-g3cr00 , 9bact-g3cr02 |