DCI-Gal-Bz
Dicyanoisophorone (DCI) large Stokes shift benzoyl as the recognition unit and Gal as the hepatocyte-targeting group
General
Type : Near-Infrared fluorescent Probe, Fluorescent Probe, Glycoside, Cyanide
Chemical_Nomenclature :
Canonical SMILES : O1C(C(C(C(C1CO)O)O)O)[N]2C=C(N=N2)COC3=CC=C(C(=C3)OC(C4=CC=CC=C4)=O)C=CC5=CC(CC(C5)(C)C)=C(C#N)C#N
InChI : InChI=1S\/C35H35N5O8\/c1-35(2)14-21(12-24(15-35)25(16-36)17-37)8-9-22-10-11-27(13-28(22)48-34(45)23-6-4-3-5-7-23)46-20-26-18-40(39-38-26)33-32(44)31(43)30(42)29(19-41)47-33\/h3-13,18,29-33,41-44H,14-15,19-20H2,1-2H3
InChIKey : HKBLHDGITLLHCH-UHFFFAOYSA-N
Other name(s) :
Target
Structures : No structure
Families : No family
References (3)
| Title : Carboxylesterase-activated hepatocyte-targeting fluorescent probe for drug-induced liver injury diagnosis - Liu_2025_Bioorg.Chem_162_108587 |
| Author(s) : Liu M , Ding C , Yi Q , Quan H , Li W , Wang Y , Lin X , Wang M , Wang J |
| Ref : Bioorg Chem , 162 :108587 , 2025 |
| Abstract : |
| PubMedSearch : Liu_2025_Bioorg.Chem_162_108587 |
| PubMedID: 40381462 |
| Title : Carboxylesterase-activated hepatocyte-targeting fluorescent probe for drug-induced liver injury diagnosis - Liu_2025_Bioorg.Chem_162_108587 |
| Author(s) : Liu M , Ding C , Yi Q , Quan H , Li W , Wang Y , Lin X , Wang M , Wang J |
| Ref : Bioorg Chem , 162 :108587 , 2025 |
| Abstract : |
| PubMedSearch : Liu_2025_Bioorg.Chem_162_108587 |
| PubMedID: 40381462 |
| Title : Carboxylesterase-activated hepatocyte-targeting fluorescent probe for drug-induced liver injury diagnosis - Liu_2025_Bioorg.Chem_162_108587 |
| Author(s) : Liu M , Ding C , Yi Q , Quan H , Li W , Wang Y , Lin X , Wang M , Wang J |
| Ref : Bioorg Chem , 162 :108587 , 2025 |
| Abstract : |
| PubMedSearch : Liu_2025_Bioorg.Chem_162_108587 |
| PubMedID: 40381462 |