DNPG
Cannot readily distinguish Lp-PLA2 from several other PAF hydrolases
General
Type : Choline ester, pNP, Trimethylammonium, Phospholipid
Chemical_Nomenclature : 2-[[3-decanoyloxy-2-[5-(4-nitrophenoxy)-5-oxopentanoyl]oxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
Canonical SMILES : CCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCC(=O)OC1=CC=C(C=C1)[N+](=O)[O-] || CCCCCCCCCC(=O)OCC(COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCCC(=O)OC1=CC=C(C=C1)[N+](=O)[O-]
InChI : InChI=1S\/C29H47N2O12P\/c1-5-6-7-8-9-10-11-13-27(32)39-22-26(23-41-44(37,38)40-21-20-31(2,3)4)43-29(34)15-12-14-28(33)42-25-18-16-24(17-19-25)30(35)36\/h16-19,26H,5-15,20-23H2,1-4H3 || InChI=1S\/C29H47N2O12P\/c1-5-6-7-8-9-10-11-13-27(32)39-22-26(23-41-44(37,38)40-21-20-31(2,3)4)43-29(34)15-12-14-28(33)42-25-18-16-24(17-19-25)30(35)36\/h16-19,26H,5-15,20-23H2,1-4H3\/p+1
InChIKey : ABZYXPGBWOWQIZ-UHFFFAOYSA-N || ABZYXPGBWOWQIZ-UHFFFAOYSA-O
Other name(s) : 1-decanoyl-2-(4-nitrophenylglutaryl)phosphatidylcholine || [3-decanoyloxy-2-[5-(4-nitrophenoxy)-5-oxopentanoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate || 2-[[3-Decanoyloxy-2-[5-(4-nitrophenoxy)-5-oxopentanoyl]oxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
MW : 646.7
Formula : C29H47N2O12P
CAS_number :
UniChem : ABZYXPGBWOWQIZ-UHFFFAOYSA-N, ABZYXPGBWOWQIZ-UHFFFAOYSA-O
Target
Structures : No structure
Families : PAF-Acetylhydrolase
References (1)
| Title : Novel General Approach for the Assay and Inhibition of Hydrolytic Enzymes Utilizing Suicide-Inhibitory Bifunctionally Linked Substrates (SIBLINKS): Exemplified by a Phospholipase A2 Assay - Washburn_1990_J.Am.Chem.Soc_112_2040 |
| Author(s) : Washburn WN , Dennis |
| Ref : Journal of the American Chemical Society , 112 :2040 , 1990 |
| Abstract : |
| PubMedSearch : Washburn_1990_J.Am.Chem.Soc_112_2040 |
| PubMedID: |
| Gene_locus related to this paper: human-PLA2G7 |