Fluorescein-dilaurate

Fluorescent synthetic substrate used for analysis of lipase activities. Can also be copolymerized in polyester for analysis enzymatic hydrolysis of polyesters (FDL-containing poly(butylene adipate))

General

Type : Fluorescent Probe, Cyclopropyl, Benzofuran, Xanthene, Dodecanoate, Laurate

Chemical_Nomenclature : (6'-dodecanoyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) dodecanoate

Canonical SMILES : CCCCCCCCCCCC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)CCCCCCCCCCC)C5=CC=CC=C5C(=O)O3

InChI : InChI=1S\/C44H56O7\/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44\/h21-24,27-32H,3-20,25-26H2,1-2H3

InChIKey : MYTRGBGGRICZGN-UHFFFAOYSA-N

Other name(s) : Fluorescein dilaurate  ||  MFCD00038409  ||  939U41013O  ||  3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl didodecanoate  ||  UNII-939U41013O  ||  EINECS 230-764-2  ||  SCHEMBL459110


MW : 696.9

Formula : C44H56O7

CAS_number : 7308-90-9

PubChem : 81743

UniChem : MYTRGBGGRICZGN-UHFFFAOYSA-N

Target

Structures : No structure

Families : Cholesterol_esterase, Lipase_3, Cutinase

References (6)

Title : Review of nomenclature and methods of analysis of polyethylene terephthalic acid hydrolyzing enzymes activity - Amanna_2023_Biodegradation__
Author(s) : Amanna R , Rakshit SK
Ref : Biodegradation , : , 2023
Abstract :
PubMedSearch : Amanna_2023_Biodegradation__
PubMedID: 37688750

Title : High-Throughput Analysis of Enzymatic Hydrolysis of Biodegradable Polyesters by Monitoring Cohydrolysis of a Polyester-Embedded Fluorogenic Probe - Zumstein_2017_Environ.Sci.Technol_51_4358
Author(s) : Zumstein MT , Kohler HE , McNeill K , Sander M
Ref : Environ Sci Technol , 51 :4358 , 2017
Abstract :
PubMedSearch : Zumstein_2017_Environ.Sci.Technol_51_4358
PubMedID: 28140581

Title : Creation of Rhizopus oryzae lipase having a unique oxyanion hole by combinatorial mutagenesis in the lid domain - Shiraga_2005_Appl.Microbiol.Biotechnol_68_779
Author(s) : Shiraga S , Ishiguro M , Fukami H , Nakao M , Ueda M
Ref : Applied Microbiology & Biotechnology , 68 :779 , 2005
Abstract :
PubMedSearch : Shiraga_2005_Appl.Microbiol.Biotechnol_68_779
PubMedID: 15729555
Gene_locus related to this paper: rhidl-lipas

Title : Biochemical tests in the diagnosis of chronic pancreatitis and in the evaluation of pancreatic insufficiency - Goldberg_1993_Clin.Biochem_26_253
Author(s) : Goldberg DM , Durie PR
Ref : Clinical Biochemistry , 26 :253 , 1993
Abstract :
PubMedSearch : Goldberg_1993_Clin.Biochem_26_253
PubMedID: 8242888

Title : Lipolytic enzymes of the human pancreas. III. Auxiliary function of lipase in the cholesterol-esterase-dependent oral test on exocrine pancreatic output - Meyer_1990_Klin.Wochenschr_68_60
Author(s) : Meyer JG , Renczes JG , Kaffarnik H
Ref : Klin Wochenschr , 68 :60 , 1990
Abstract :
PubMedSearch : Meyer_1990_Klin.Wochenschr_68_60
PubMedID: 2319733

Title : Properties of a membrane-bound triglyceride lipase of rapeseed (Brassica napus L.) cotyledons - Rosnitschek_1980_Planta_148_193
Author(s) : Rosnitschek I , Theimer RR
Ref : Planta , 148 :193 , 1980
Abstract :
PubMedSearch : Rosnitschek_1980_Planta_148_193
PubMedID: 24309818