Fumonisin-B1

General

Type : Mycotoxin-metabolite, Natural, Toxin

Chemical_Nomenclature : 2-[2-[19-amino-6-(3,4-dicarboxybutanoyloxy)-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid

Canonical SMILES : CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O

InChI : InChI=1S\/C34H59NO15\/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35\/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)

InChIKey : UVBUBMSSQKOIBE-UHFFFAOYSA-N

Other name(s) : Fumonisin b1  ||  Macrofusine  ||  Fusarium moniliforme  ||  NSC629151  ||  FB1


MW : 721.82

Formula : C34H59NO15

CAS_number : 116355-83-0

PubChem : 3431

UniChem : UVBUBMSSQKOIBE-UHFFFAOYSA-N

Wikipedia : Fumonisin_B1

Target

Families : Carb_B_Bacteria

References (10)

Title : Comparison Study of Two Fumonisin-Degrading Enzymes for Detoxification in Piglets - Wang_2024_Toxins.(Basel)_16_3
Author(s) : Wang Z , Lv Z , Czabany T , Nagl V , Krska R , Wang X , Han B , Tao H , Liu J , Wang J
Ref : Toxins (Basel) , 16 :3 , 2024
Abstract :
PubMedSearch : Wang_2024_Toxins.(Basel)_16_3
PubMedID: 38276527
Gene_locus related to this paper: sphmc-FumD , 9sphn-a0a101vlk1

Title : Optimization Workflow of Fumonisin Esterase Production for Biocatalytic Degradation of Fumonisin B(1) - Incze_2023_Life.(Basel)_13_1885
Author(s) : Incze DJ , Poppe L , Bata Z
Ref : Life (Basel) , 13 : , 2023
Abstract :
PubMedSearch : Incze_2023_Life.(Basel)_13_1885
PubMedID: 37763289
Gene_locus related to this paper: uncxx-CFE

Title : Biodegradation of Fumonisins by the Consecutive Action of a Fusion Enzyme - Li_2022_Toxins.(Basel)_14_
Author(s) : Li K , Yu S , Yu D , Lin H , Liu N , Wu A
Ref : Toxins (Basel) , 14 : , 2022
Abstract :
PubMedSearch : Li_2022_Toxins.(Basel)_14_
PubMedID: 35448875
Gene_locus related to this paper: sphmc-FumD

Title : FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs - Liu_2022_Food.Addit.Contam.Part.A.Chem.Anal.Control.Expo.Risk.Assess__
Author(s) : Liu Q , Huang L , Cui Z , Qiao B , Li F , Wang C
Ref : Food Additives & Contaminants Part A Chem Anal Control Expo Risk Assess , :1 , 2022
Abstract :
PubMedSearch : Liu_2022_Food.Addit.Contam.Part.A.Chem.Anal.Control.Expo.Risk.Assess__
PubMedID: 35858108
Gene_locus related to this paper: sphmc-FumD , 9sphn-a0a101vlk1

Title : FumDSB Can Reduce the Toxic Effects of Fumonisin B(1) by Regulating Several Brain-Gut Peptides in Both the Hypothalamus and Jejunum of Growing Pigs - Liu_2021_Toxins.(Basel)_13_874
Author(s) : Liu Q , Li F , Huang L , Chen W , Li Z , Wang C
Ref : Toxins (Basel) , 13 :874 , 2021
Abstract :
PubMedSearch : Liu_2021_Toxins.(Basel)_13_874
PubMedID: 34941712
Gene_locus related to this paper: 9sphn-a0a101vlk1

Title : Biological detoxification of fumonisin by a novel carboxylesterase from Sphingomonadales bacterium and its biochemical characterization - Li_2021_Int.J.Biol.Macromol_169_18
Author(s) : Li Z , Wang Y , Liu Z , Jin S , Pan K , Liu H , Liu T , Li X , Zhang C , Luo X , Song Y , Zhao J , Zhang T
Ref : Int J Biol Macromol , 169 :18 , 2021
Abstract :
PubMedSearch : Li_2021_Int.J.Biol.Macromol_169_18
PubMedID: 33309671
Gene_locus related to this paper: 9sphn-a0a101vlk1

Title : The efficacy and effect on gut microbiota of an aflatoxin binder and a fumonisin esterase using an in vitro simulator of the human intestinal microbial ecosystem (SHIME) - Neckermann_2021_Food.Res.Int_145_110395
Author(s) : Neckermann K , Claus G , De Baere S , Antonissen G , Lebrun S , Gemmi C , Taminiau B , Douny C , Scippo ML , Schatzmayr D , Gathumbi J , Uhlig S , Croubels S , Delcenserie V
Ref : Food Res Int , 145 :110395 , 2021
Abstract :
PubMedSearch : Neckermann_2021_Food.Res.Int_145_110395
PubMedID: 34112398

Title : Detoxification of the Fumonisin Mycotoxins in Maize: An Enzymatic Approach - Alberts_2019_Toxins.(Basel)_11_523
Author(s) : Alberts J , Schatzmayr G , Moll WD , Davids I , Rheeder J , Burger HM , Shephard G , Gelderblom W
Ref : Toxins (Basel) , 11 : , 2019
Abstract :
PubMedSearch : Alberts_2019_Toxins.(Basel)_11_523
PubMedID: 31510008
Gene_locus related to this paper: sphmc-FumD

Title : Gastrointestinal Degradation of Fumonisin B(1) by Carboxylesterase FumD Prevents Fumonisin Induced Alteration of Sphingolipid Metabolism in Turkey and Swine - Masching_2016_Toxins.(Basel)_8_
Author(s) : Masching S , Naehrer K , Schwartz-Zimmermann HE , Sarandan M , Schaumberger S , Dohnal I , Nagl V , Schatzmayr D
Ref : Toxins (Basel) , 8 : , 2016
Abstract :
PubMedSearch : Masching_2016_Toxins.(Basel)_8_
PubMedID: 27007395
Gene_locus related to this paper: sphmc-FumD

Title : Degradation of fumonisin B1 by the consecutive action of two bacterial enzymes - Heinl_2010_J.Biotechnol_145_120
Author(s) : Heinl S , Hartinger D , Thamhesl M , Vekiru E , Krska R , Schatzmayr G , Moll WD , Grabherr R
Ref : J Biotechnol , 145 :120 , 2010
Abstract :
PubMedSearch : Heinl_2010_J.Biotechnol_145_120
PubMedID: 19922747
Gene_locus related to this paper: sphmc-FumD