Methyl-3-hydroxy-2-methylpropanoate
Substrate used to test enantioselectivity. Also substrate of SGNH hydrolase and Beta-lactamase esterase VIII
General
Type : Propionate
Chemical_Nomenclature : methyl (2S)-3-hydroxy-2-methylpropanoate
Canonical SMILES : CC(CO)C(=O)OC
InChI : InChI=1S\/C5H10O3\/c1-4(3-6)5(7)8-2\/h4,6H,3H2,1-2H3\/t4-\/m0\/s1 || InChI=1S\/C5H10O3\/c1-4(3-6)5(7)8-2\/h4,6H,3H2,1-2H3
InChIKey : ATCCIZURPPEVIZ-BYPYZUCNSA-N || ATCCIZURPPEVIZ-UHFFFAOYSA-N
Other name(s) : S-methyl-3-hydroxy-2-methylpropionate || (S)-Methyl 3-hydroxy-2-methylpropanoate || Methyl (S)-(+)-3-hydroxy-2-methylpropionate || Methyl (2S)-3-hydroxy-2-methylpropanoate || (+)-Methyl L-beta-hydroxyisobutyrate || Methyl 3-hydroxy-2-methylpropanoate || 3-Hydroxyisobutyric acid methyl ester || Propanoic acid, 3-hydroxy-2-methyl-, methyl ester || MFCD00063450 || SCHEMBL86348
MW : 118.13
Formula : C5H10O3
CAS_number : 80657-57-4, 42998-03-8
PubChem : 10192563, 521128, 5324733
UniChem : ATCCIZURPPEVIZ-BYPYZUCNSA-N, ATCCIZURPPEVIZ-UHFFFAOYSA-N
Target
Structures : No structure
Families : Lipase_2
References (3)
| Title : Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum - Lee_2017_PLoS.One_12_e0169540 |
| Author(s) : Lee CW , Kwon S , Park SH , Kim BY , Yoo W , Ryu BH , Kim HW , Shin SC , Kim S , Park H , Kim TD , Lee JH |
| Ref : PLoS ONE , 12 :e0169540 , 2017 |
| Abstract : |
| PubMedSearch : Lee_2017_PLoS.One_12_e0169540 |
| PubMedID: 28125606 |
| Gene_locus related to this paper: exiab-k0acl0 |
| Title : Characterization of an Alkaline Family I.4 Lipase from Bacillus sp. W130-35 Isolated from a Tidal Mud Flat with Broad Substrate Specificity - Kim_2015_J.Microbiol.Biotechnol_25_2024 |
| Author(s) : Kim HJ , Jung WK , Lee HW , Yoo W , Kim TD , Kim H |
| Ref : J Microbiol Biotechnol , 25 :2024 , 2015 |
| Abstract : |
| PubMedSearch : Kim_2015_J.Microbiol.Biotechnol_25_2024 |
| PubMedID: 26370800 |
| Gene_locus related to this paper: bacpu-w8rkh7 |
| Title : Inverting enantioselectivity of Burkholderia gladioli esterase EstB by directed and designed evolution - Ivancic_2007_J.Biotechnol_129_109 |
| Author(s) : Ivancic M , Valinger G , Gruber K , Schwab H |
| Ref : J Biotechnol , 129 :109 , 2007 |
| Abstract : |
| PubMedSearch : Ivancic_2007_J.Biotechnol_129_109 |
| PubMedID: 17147964 |