Spirodiclofen

General

Type : Organochlorine, Acaricide

Chemical_Nomenclature : [3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl] 2,2-dimethylbutanoate

Canonical SMILES : CCC(C)(C)C(=O)OC1=C(C(=O)OC12CCCCC2)C3=C(C=C(C=C3)Cl)Cl

InChI : InChI=1S\/C21H24Cl2O4\/c1-4-20(2,3)19(25)26-17-16(14-9-8-13(22)12-15(14)23)18(24)27-21(17)10-6-5-7-11-21\/h8-9,12H,4-7,10-11H2,1-3H3

InChIKey : DTDSAWVUFPGDMX-UHFFFAOYSA-N

Other name(s) : UNII-3X7G31F5MX  ||  3X7G31F5MX  ||  CHEBI:38639  ||  ZINC2540062  ||  SCHEMBL27234  ||  CHEMBL2227839  ||  Butanoic acid, 2,2-dimethyl-, 3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro(4.5)dec-3-en-4-yl ester


MW : 411.3

Formula : C21H24Cl2O4

CAS_number : 148477-71-8

PubChem : 177863

UniChem : DTDSAWVUFPGDMX-UHFFFAOYSA-N

Target

Structures : No structure

Families : Cholinesterase-like

References (3)

Title : Overexpression of an alternative allele of carboxyl\/choline esterase 4 (CCE04) of Tetranychus urticae is associated with high levels of resistance to the keto-enol acaricide spirodiclofen - Wei_2020_Pest.Manag.Sci_76_1142
Author(s) : Wei P , Demaeght P , De Schutter K , Grigoraki L , Labropoulou V , Riga M , Vontas J , Nauen R , Dermauw W , Van Leeuwen T
Ref : Pest Manag Sci , 76 :1142 , 2020
Abstract :
PubMedSearch : Wei_2020_Pest.Manag.Sci_76_1142
PubMedID: 31583806
Gene_locus related to this paper: tetur-t1jsj6 , tetur-t1jth6

Title : Transcriptome profiling of a spirodiclofen susceptible and resistant strain of the European red mite Panonychus ulmi using strand-specific RNA-seq - Bajda_2015_BMC.Genomics_16_974
Author(s) : Bajda S , Dermauw W , Greenhalgh R , Nauen R , Tirry L , Clark RM , Van Leeuwen T
Ref : BMC Genomics , 16 :974 , 2015
Abstract :
PubMedSearch : Bajda_2015_BMC.Genomics_16_974
PubMedID: 26581334

Title : Molecular analysis of resistance to acaricidal spirocyclic tetronic acids in Tetranychus urticae: CYP392E10 metabolizes spirodiclofen, but not its corresponding enol - Demaeght_2013_Insect.Biochem.Mol.Biol_43_544
Author(s) : Demaeght P , Dermauw W , Tsakireli D , Khajehali J , Nauen R , Tirry L , Vontas J , Lummen P , Van Leeuwen T
Ref : Insect Biochemistry & Molecular Biology , 43 :544 , 2013
Abstract :
PubMedSearch : Demaeght_2013_Insect.Biochem.Mol.Biol_43_544
PubMedID: 23523619