| Title : Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease - Wu_2024_Molecules_29_ |
| Author(s) : Wu X , Ze X , Qin S , Zhang B , Li X , Gong Q , Zhang H , Zhu Z , Xu J |
| Ref : Molecules , 29 : , 2024 |
| Abstract : |
| PubMedSearch : Wu_2024_Molecules_29_ |
| PubMedID: 38675602 |
| Title : UHPLC-Q\/Orbitrap HRMS combined with spectrum-effect relationship and network pharmacology to discovery the gastrointestinal motility-promoting material basis in Citri Sarcodactylis Fructus - Liu_2024_J.Ethnopharmacol_337_118926 |
| Author(s) : Liu X , Gong Q , Deng X , Li L , Luo R , Li X , Guo D , Deng F |
| Ref : J Ethnopharmacol , 337 :118926 , 2024 |
| Abstract : |
| PubMedSearch : Liu_2024_J.Ethnopharmacol_337_118926 |
| PubMedID: 39393559 |
| Title : Novel inhibitors of AChE and Abeta aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease - Liu_2022_Eur.J.Med.Chem_235_114305 |
| Author(s) : Liu Y , Uras G , Onuwaje I , Li W , Yao H , Xu S , Li X , Phillips J , Allen S , Gong Q , Zhang H , Zhu Z , Liu J , Xu J |
| Ref : Eur Journal of Medicinal Chemistry , 235 :114305 , 2022 |
| Abstract : |
| PubMedSearch : Liu_2022_Eur.J.Med.Chem_235_114305 |
| PubMedID: 35339839 |
| Title : Structural and biochemical mechanisms of NLRP1 inhibition by DPP9 - Huang_2021_Nature__ |
| Author(s) : Huang M , Zhang X , Toh GA , Gong Q , Wang J , Han Z , Wu B , Zhong F , Chai J |
| Ref : Nature , : , 2021 |
| Abstract : |
| PubMedSearch : Huang_2021_Nature__ |
| PubMedID: 33731929 |
| Gene_locus related to this paper: rat-dpp9 |
| Title : Discovery of Novel Tacrine-Pyrimidone Hybrids as Potent Dual AChE\/GSK-3 Inhibitors for the Treatment of Alzheimer's Disease - Yao_2021_J.Med.Chem__ |
| Author(s) : Yao H , Uras G , Zhang P , Xu S , Yin Y , Liu J , Qin S , Li X , Allen S , Bai R , Gong Q , Zhang H , Zhu Z , Xu J |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Yao_2021_J.Med.Chem__ |
| PubMedID: 34024109 |
| Title : Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate - Zhou_2021_J.Med.Chem_64_1844 |
| Author(s) : Zhou Y , Fu Y , Yin W , Li J , Wang W , Bai F , Xu S , Gong Q , Peng T , Hong Y , Zhang D , Liu Q , Xu Y , Xu HE , Zhang H , Jiang H , Liu H |
| Ref : Journal of Medicinal Chemistry , 64 :1844 , 2021 |
| Abstract : |
| PubMedSearch : Zhou_2021_J.Med.Chem_64_1844 |
| PubMedID: 33570950 |
| Gene_locus related to this paper: human-ACHE |
| Title : The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression - Li_2021_Eur.J.Med.Chem_229_114045 |
| Author(s) : Li X , Li J , Huang Y , Gong Q , Fu Y , Xu Y , Huang J , You H , Zhang D , Mao F , Zhu J , Wang H , Zhang H |
| Ref : Eur Journal of Medicinal Chemistry , 229 :114045 , 2021 |
| Abstract : |
| PubMedSearch : Li_2021_Eur.J.Med.Chem_229_114045 |
| PubMedID: 34922191 |
| Title : Identification of genes involved in sex pheromone biosynthesis and metabolic pathway in the Chinese oak silkworm, Antheraea pernyi - Wang_2020_Int.J.Biol.Macromol_163_1487 |
| Author(s) : Wang QH , Gong Q , Fang SM , Liu YQ , Zhang Z , Yu QY |
| Ref : Int J Biol Macromol , 163 :1487 , 2020 |
| Abstract : |
| PubMedSearch : Wang_2020_Int.J.Biol.Macromol_163_1487 |
| PubMedID: 32755713 |
| Title : Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) - Ni_2018_ACS.Chem.Neurosci_9_1625 |
| Author(s) : Ni W , Wang H , Li X , Zheng X , Wang M , Zhang J , Gong Q , Ling D , Mao F , Zhang H , Li J |
| Ref : ACS Chem Neurosci , 9 :1625 , 2018 |
| Abstract : |
| PubMedSearch : Ni_2018_ACS.Chem.Neurosci_9_1625 |
| PubMedID: 29616790 |
| Title : A novel non-enzymatic hydrolytic probe for dipeptidyl peptidase IV specific recognition and imaging - Xing_2018_Chem.Commun.(Camb)_54_8773 |
| Author(s) : Xing J , Gong Q , Zhang R , Sun S , Zou R , Wu A |
| Ref : Chem Commun (Camb) , 54 :8773 , 2018 |
| Abstract : |
| PubMedSearch : Xing_2018_Chem.Commun.(Camb)_54_8773 |
| PubMedID: 30035284 |
| Title : Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation - Li_2017_ACS.Chem.Neurosci_8_2708 |
| Author(s) : Li X , Wang H , Xu Y , Liu W , Gong Q , Wang W , Qiu X , Zhu J , Mao F , Zhang H , Li J |
| Ref : ACS Chem Neurosci , 8 :2708 , 2017 |
| Abstract : |
| PubMedSearch : Li_2017_ACS.Chem.Neurosci_8_2708 |
| PubMedID: 28872831 |
| Title : Ultrasensitive Fluorescent Probes Reveal an Adverse Action of Dipeptide Peptidase IV and Fibroblast Activation Protein during Proliferation of Cancer Cells - Gong_2016_Anal.Chem_88_8309 |
| Author(s) : Gong Q , Shi W , Li L , Wu X , Ma H |
| Ref : Analytical Chemistry , 88 :8309 , 2016 |
| Abstract : |
| PubMedSearch : Gong_2016_Anal.Chem_88_8309 |
| PubMedID: 27444320 |
| Title : Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease - Huang_2014_Neurobiol.Aging_35_1045 |
| Author(s) : Huang XT , Qian ZM , He X , Gong Q , Wu KC , Jiang LR , Lu LN , Zhu ZJ , Zhang HY , Yung WH , Ke Y |
| Ref : Neurobiology of Aging , 35 :1045 , 2014 |
| Abstract : |
| PubMedSearch : Huang_2014_Neurobiol.Aging_35_1045 |
| PubMedID: 24332448 |
| Title : Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase - Zhu_2009_Bioorg.Med.Chem_17_1600 |
| Author(s) : Zhu Y , Xiao K , Ma L , Xiong B , Fu Y , Yu H , Wang W , Wang X , Hu D , Peng H , Li J , Gong Q , Chai Q , Tang X , Zhang H , Shen J |
| Ref : Bioorganic & Medicinal Chemistry , 17 :1600 , 2009 |
| Abstract : |
| PubMedSearch : Zhu_2009_Bioorg.Med.Chem_17_1600 |
| PubMedID: 19162488 |
| Title : Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells - Chipitsyna_2009_Int.J.Cancer_125_276 |
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| Ref : International Journal of Cancer , 125 :276 , 2009 |
| Abstract : |
| PubMedSearch : Chipitsyna_2009_Int.J.Cancer_125_276 |
| PubMedID: 19358273 |
| Title : Localization and regulation of low affinity nerve growth factor receptor expression in the rat olfactory system during development and regeneration - Gong_1994_J.Comp.Neurol_344_336 |
| Author(s) : Gong Q , Bailey MS , Pixley SK , Ennis M , Liu W , Shipley MT |
| Ref : Journal of Comparative Neurology , 344 :336 , 1994 |
| Abstract : |
| PubMedSearch : Gong_1994_J.Comp.Neurol_344_336 |
| PubMedID: 8063958 |