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Substrate Report for: 2,6-Dichlorophenolindophenyl-acetate

Chromogenic substrate for human AChE Km 38.0 microM and 244 pkat


General
Type Acetate, Indole, Chromogen
Chemical_Nomenclature [4-[(3,5-dichloro-4-oxocyclohexa-2,5-dien-1-ylidene)amino]phenyl] acetate
Canonical SMILES CC(=O)OC1=CC=C(C=C1)N=C2C=C(C(=O)C(=C2)Cl)Cl
InChI InChI=1S/C14H9Cl2NO3/c1-8(18)20-11-4-2-9(3-5-11)17-10-6-12(15)14(19)13(16)7-10/h2-7H,1H3
InChIKey TTWHMYKNQLOAIV-UHFFFAOYSA-N
Other name(s) 2,6-Dichlorophenolindophenyl acetate ; 2,6-dichloroindophenol acetate ; dichloroindophenol acetate ; DIPhA ; SCHEMBL18605938 ; DTXSID80885276 ; NSC90576 ; ZINC4916805
________________________________________________________________________________________________
MW|310.1
Formula|C14H9Cl2NO3
CAS_number|24857-20-3
PubChem|259864
UniChem|TTWHMYKNQLOAIV-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | 2,6-Dichlorophenolindophenyl-acetate ligand of proteins in family: ACHE, BCHE
Protein | human-ACHE, human-BCHE

References:
Search PubMed for references concerning: 2,6-Dichlorophenolindophenyl-acetate

3 more
    Title: A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity
    Pohanka M, Zakova J
    Ref: Sensors (Basel), 21:, 2021 : PubMed

            

    Title: Evaluation of 2,6-dichlorophenolindophenol acetate as a substrate for acetylcholinesterase activity assay
    Pohanka M, Holas O
    Ref: J Enzyme Inhib Med Chem, 30:796, 2015 : PubMed

            

    Title: Spectrophotometric methods based on 2,6-dichloroindophenol acetate and indoxylacetate for butyrylcholinesterase activity assay in plasma
    Pohanka M, Drtinova L
    Ref: Talanta, 106:281, 2013 : PubMed