Dehydrosecodine
General
Type : Alkaloid || Indole || Natural
Chemical_Nomenclature : methyl 2-[3-[2-(5-ethyl-2H-pyridin-1-yl)ethyl]-1H-indol-2-yl]prop-2-enoate
Canonical SMILES : CCC1=CN(CC=C1)CCC2=C(NC3=CC=CC=C32)C(=C)C(=O)OC
InChI : InChI=1S\/C21H24N2O2\/c1-4-16-8-7-12-23(14-16)13-11-18-17-9-5-6-10-19(17)22-20(18)15(2)21(24)25-3\/h5-10,14,22H,2,4,11-13H2,1,3H3
InChIKey : FGHJSNGBTCVANJ-UHFFFAOYSA-N
Other name(s) : CHEBI:146301, DTXSID201032252, Dehydrosecodine(1+), CHEBI:146237
MW : 336.4
Formula : C21H24N2O2
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : Plant_carboxylesterase
References (3)
| Title : Evolution and diversification of carboxylesterase-like [4+2] cyclases in aspidosperma and iboga alkaloid biosynthesis - DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| Author(s) : DeMars MD, 2nd , O'Connor SE |
| Ref : Proc Natl Acad Sci U S A , 121 :e2318586121 , 2024 |
| Abstract : DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| ESTHER : DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| PubMedSearch : DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| PubMedID: 38319969 |
| Gene_locus related to this paper: catro-CS , catro-TS , tabib-a0a5b8x6s2 , tabib-CorS |
| Title : Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids - Caputi_2020_Nat.Chem.Biol_16_383 |
| Author(s) : Caputi L , Franke J , Bussey K , Farrow SC , Vieira IJC , Stevenson CEM , Lawson DM , O'Connor SE |
| Ref : Nat Chemical Biology , 16 :383 , 2020 |
| Abstract : Caputi_2020_Nat.Chem.Biol_16_383 |
| ESTHER : Caputi_2020_Nat.Chem.Biol_16_383 |
| PubMedSearch : Caputi_2020_Nat.Chem.Biol_16_383 |
| PubMedID: 32066966 |
| Gene_locus related to this paper: catro-CS , catro-TS , tabib-a0a5b8x6s2 , tabib-CorS |
| Title : Biogenetically inspired synthesis and skeletal diversification of indole alkaloids - Mizoguchi_2014_Nat.Chem_6_57 |
| Author(s) : Mizoguchi H , Oikawa H , Oguri H |
| Ref : Nat Chem , 6 :57 , 2014 |
| Abstract : Mizoguchi_2014_Nat.Chem_6_57 |
| ESTHER : Mizoguchi_2014_Nat.Chem_6_57 |
| PubMedSearch : Mizoguchi_2014_Nat.Chem_6_57 |
| PubMedID: 24345948 |