Dihydroprecondylocarpine-acetate
General
Type : Indole || Alkaloid || Natural
Chemical_Nomenclature : methyl (1S,2S)-2-(acetyloxymethyl)-16-ethyl-4-aza-14-azoniatetracyclo[12.2.2.03,11.05,10]octadeca-3(11),5,7,9,14-pentaene-2-carboxylate
Canonical SMILES : CCC1C=[N+]2CCC1C(C3=C(CC2)C4=CC=CC=C4N3)(COC(=O)C)C(=O)OC
InChI : InChI=1S\/C23H29N2O4\/c1-4-16-13-25-11-9-18-17-7-5-6-8-20(17)24-21(18)23(22(27)28-3,14-29-15(2)26)19(16)10-12-25\/h5-8,13,16,19,24H,4,9-12,14H2,1-3H3\/q+1\/t16?,19-,23-\/m0\/s1
InChIKey : QXQMGTOURBIIKD-RUMUXARQSA-N
Other name(s) : dihydroprecondylocarpine acetate, CHEBI:142770, (6S,7S)-7-(acetoxymethyl)-5-ethyl-7-(methoxycarbonyl)-1,2,5,6,7,8-hexahydro-3,6-ethanoazonino[5,4-b]indol-3-ium
MW : 397.5
Formula : C23H29N2O4+
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : Plant_carboxylesterase
References (4)
| Title : Evolution and diversification of carboxylesterase-like [4+2] cyclases in aspidosperma and iboga alkaloid biosynthesis - DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| Author(s) : DeMars MD, 2nd , O'Connor SE |
| Ref : Proc Natl Acad Sci U S A , 121 :e2318586121 , 2024 |
| Abstract : DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| ESTHER : DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| PubMedSearch : DeMars_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2318586121 |
| PubMedID: 38319969 |
| Gene_locus related to this paper: catro-CS , catro-TS , tabib-a0a5b8x6s2 , tabib-CorS |
| Title : Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids - Caputi_2020_Nat.Chem.Biol_16_383 |
| Author(s) : Caputi L , Franke J , Bussey K , Farrow SC , Vieira IJC , Stevenson CEM , Lawson DM , O'Connor SE |
| Ref : Nat Chemical Biology , 16 :383 , 2020 |
| Abstract : Caputi_2020_Nat.Chem.Biol_16_383 |
| ESTHER : Caputi_2020_Nat.Chem.Biol_16_383 |
| PubMedSearch : Caputi_2020_Nat.Chem.Biol_16_383 |
| PubMedID: 32066966 |
| Gene_locus related to this paper: catro-CS , catro-TS , tabib-a0a5b8x6s2 , tabib-CorS |
| Title : Completion of the canonical pathway for assembly of anticancer drugs vincristine\/vinblastine in Catharanthus roseus - Qu_2019_Plant.J_97_257 |
| Author(s) : Qu Y , Safonova O , De Luca V |
| Ref : Plant J , 97 :257 , 2019 |
| Abstract : Qu_2019_Plant.J_97_257 |
| ESTHER : Qu_2019_Plant.J_97_257 |
| PubMedSearch : Qu_2019_Plant.J_97_257 |
| PubMedID: 30256480 |
| Gene_locus related to this paper: catro-hl3 , catro-hl4 |
| Title : Solution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19E-geissoschizine - Qu_2018_Proc.Natl.Acad.Sci.U.S.A_115_3180 |
| Author(s) : Qu Y , Easson M , Simionescu R , Hajicek J , Thamm AMK , Salim V , De Luca V |
| Ref : Proc Natl Acad Sci U S A , 115 :3180 , 2018 |
| Abstract : Qu_2018_Proc.Natl.Acad.Sci.U.S.A_115_3180 |
| ESTHER : Qu_2018_Proc.Natl.Acad.Sci.U.S.A_115_3180 |
| PubMedSearch : Qu_2018_Proc.Natl.Acad.Sci.U.S.A_115_3180 |
| PubMedID: 29511102 |
| Gene_locus related to this paper: catro-CS , catro-TS , catro-hl3 , catro-hl4 |