Flupirtine
General
Type : Pro-Drug || Drug || Not A\/B H target || Carbamate
Chemical_Nomenclature : ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate
Canonical SMILES : CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N
InChI : InChI=1S\/C15H17FN4O2\/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10\/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20)
InChIKey : JUUFBMODXQKSTD-UHFFFAOYSA-N
Other name(s) : D 9998, MOH3ET196H
Target
Families : Carb_B_Chordata
References (1)
| Title : In vitro approach to elucidate the relevance of carboxylesterase 2 and N-acetyltransferase 2 to flupirtine-induced liver injury - Konishi_2018_Biochem.Pharmacol_155_242 |
| Author(s) : Konishi K , Fukami T , Ogiso T , Nakajima M |
| Ref : Biochemical Pharmacology , 155 :242 , 2018 |
| Abstract : Konishi_2018_Biochem.Pharmacol_155_242 |
| ESTHER : Konishi_2018_Biochem.Pharmacol_155_242 |
| PubMedSearch : Konishi_2018_Biochem.Pharmacol_155_242 |
| PubMedID: 30028988 |