| Title : Role of carboxylesterase and arylacetamide deacetylase in drug metabolism, physiology, and pathology - Nagaoka_2024_Biochem.Pharmacol__116128 |
| Author(s) : Nagaoka M , Sakai Y , Nakajima M , Fukami T |
| Ref : Biochemical Pharmacology , :116128 , 2024 |
| Abstract : |
| PubMedSearch : Nagaoka_2024_Biochem.Pharmacol__116128 |
| PubMedID: 38492781 |
| Gene_locus related to this paper: human-AADAC , human-CES1 , human-CES2 |
| Title : Evaluation of drug-drug interactions via inhibition of hydrolases by orlistat, an anti-obesity drug - Hirosawa_2023_Drug.Metab.Dispos__ |
| Author(s) : Hirosawa K , Fukami T , Nakano M , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2023 |
| Abstract : |
| PubMedSearch : Hirosawa_2023_Drug.Metab.Dispos__ |
| PubMedID: 37137721 |
| Title : Characterization of Enzymes Involved in Nintedanib Metabolism in Humans - Nakashima_2023_Drug.Metab.Dispos_51_733 |
| Author(s) : Nakashima S , Sato R , Fukami T , Kudo T , Hashiba S , Morinaga G , Nakano M , Ludwig-Schwellinger E , Matsui A , Ishiguro N , Ebner T , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 51 :733 , 2023 |
| Abstract : |
| PubMedSearch : Nakashima_2023_Drug.Metab.Dispos_51_733 |
| PubMedID: 36927840 |
| Title : In vitro deacetylation of N-acetylserotonin by arylacetamide deacetylase - Huang_2023_J.Pineal.Res_75_e12870 |
| Author(s) : Huang Z , Li Y , Konishi K , Sakai Y , Tashiro K , Fukami T , Borjigin J |
| Ref : J Pineal Res , 75 :e12870 , 2023 |
| Abstract : |
| PubMedSearch : Huang_2023_J.Pineal.Res_75_e12870 |
| PubMedID: 37002641 |
| Title : Arylacetamide deacetylase knockout mice are sensitive to ketoconazole-induced hepatotoxicity and adrenal insufficiency - Nagaoka_2022_Biochem.Pharmacol_195_114842 |
| Author(s) : Nagaoka M , Fukami T , Kisui F , Yamada T , Sakai Y , Tashiro K , Ogiso T , Konishi K , Honda S , Hirosawa K , Nakano M , Nakajima M |
| Ref : Biochemical Pharmacology , 195 :114842 , 2022 |
| Abstract : |
| PubMedSearch : Nagaoka_2022_Biochem.Pharmacol_195_114842 |
| PubMedID: 34798123 |
| Gene_locus related to this paper: mouse-aryla |
| Title : PPARalpha regulates the expression of human arylacetamide deacetylase involved in drug hydrolysis and lipid metabolism - Morikawa_2022_Biochem.Pharmacol_199_115010 |
| Author(s) : Morikawa T , Fukami T , Gotoh-Saito S , Nakano M , Nakajima M |
| Ref : Biochemical Pharmacology , 199 :115010 , 2022 |
| Abstract : |
| PubMedSearch : Morikawa_2022_Biochem.Pharmacol_199_115010 |
| PubMedID: 35314168 |
| Title : Role of human AADAC on hydrolysis of eslicarbazepine acetate and effects of AADAC genetic polymorphisms on hydrolase activity - Hirosawa_2021_Drug.Metab.Dispos__ |
| Author(s) : Hirosawa K , Fukami T , Tashiro K , Sakai Y , Kisui F , Nakano M , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2021 |
| Abstract : |
| PubMedSearch : Hirosawa_2021_Drug.Metab.Dispos__ |
| PubMedID: 33446525 |
| Gene_locus related to this paper: human-AADAC |
| Title : Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans - Sakai_2021_Life.Sci_284_119896 |
| Author(s) : Sakai Y , Fukami T , Nagaoka M , Hirosawa K , Ichida H , Sato R , Suzuki K , Nakano M , Nakajima M |
| Ref : Life Sciences , 284 :119896 , 2021 |
| Abstract : |
| PubMedSearch : Sakai_2021_Life.Sci_284_119896 |
| PubMedID: 34450168 |
| Gene_locus related to this paper: mouse-aryla |
| Title : Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase - Yasuda_2021_Drug.Metab.Pharmacokinet_39_100397 |
| Author(s) : Yasuda K , Watanabe K , Fukami T , Nakashima S , Ikushiro SI , Nakajima M , Sakaki T |
| Ref : Drug Metab Pharmacokinet , 39 :100397 , 2021 |
| Abstract : |
| PubMedSearch : Yasuda_2021_Drug.Metab.Pharmacokinet_39_100397 |
| PubMedID: 34171773 |
| Title : m(6)A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2 - Takemoto_2021_Biochem.Pharmacol__114766 |
| Author(s) : Takemoto S , Nakano M , Fukami T , Nakajima M |
| Ref : Biochemical Pharmacology , :114766 , 2021 |
| Abstract : |
| PubMedSearch : Takemoto_2021_Biochem.Pharmacol__114766 |
| PubMedID: 34536357 |
| Title : Hydrolase activities of cynomolgus monkey liver microsomes and recombinant CES1, CES2, and AADAC - Honda_2021_Eur.J.Pharm.Sci__105807 |
| Author(s) : Honda S , Fukami T , Tsujiguchi T , Zhang Y , Nakano M , Nakajima M |
| Ref : Eur J Pharm Sci , :105807 , 2021 |
| Abstract : |
| PubMedSearch : Honda_2021_Eur.J.Pharm.Sci__105807 |
| PubMedID: 33722734 |
| Title : Differences in hydrolase activities in the liver and small intestine between marmosets and humans - Honda_2021_Drug.Metab.Dispos__ |
| Author(s) : Honda S , Fukami T , Hirosawa K , Tsujiguchi T , Zhang Y , Nakano M , Uehara S , Uno Y , Yamazaki H , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2021 |
| Abstract : |
| PubMedSearch : Honda_2021_Drug.Metab.Dispos__ |
| PubMedID: 34135089 |
| Title : Strain and sex differences in drug hydrolase activities in rodent livers - Kisui_2019_Eur.J.Pharm.Sci__105143 |
| Author(s) : Kisui F , Fukami T , Nakano M , Nakajima M |
| Ref : Eur J Pharm Sci , :105143 , 2019 |
| Abstract : |
| PubMedSearch : Kisui_2019_Eur.J.Pharm.Sci__105143 |
| PubMedID: 31726091 |
| Title : In vitro approach to elucidate the relevance of carboxylesterase 2 and N-acetyltransferase 2 to flupirtine-induced liver injury - Konishi_2018_Biochem.Pharmacol_155_242 |
| Author(s) : Konishi K , Fukami T , Ogiso T , Nakajima M |
| Ref : Biochemical Pharmacology , 155 :242 , 2018 |
| Abstract : |
| PubMedSearch : Konishi_2018_Biochem.Pharmacol_155_242 |
| PubMedID: 30028988 |
| Title : Difference in substrate specificity of carboxylesterase and arylacetamide deacetylase between dogs and humans - Yoshida_2018_Eur.J.Pharm.Sci_111_167 |
| Author(s) : Yoshida T , Fukami T , Kurokawa T , Gotoh S , Oda A , Nakajima M |
| Ref : Eur J Pharm Sci , 111 :167 , 2018 |
| Abstract : |
| PubMedSearch : Yoshida_2018_Eur.J.Pharm.Sci_111_167 |
| PubMedID: 28966098 |
| Gene_locus related to this paper: canfa-CESDD1 , canfa-f1p6w8 , canlf-e2r2h2 |
| Title : Identification of enzymes responsible for nitrazepam metabolism and toxicity in human - Konishi_2017_Biochem.Pharmacol_140_150 |
| Author(s) : Konishi K , Fukami T , Gotoh S , Nakajima M |
| Ref : Biochemical Pharmacology , 140 :150 , 2017 |
| Abstract : |
| PubMedSearch : Konishi_2017_Biochem.Pharmacol_140_150 |
| PubMedID: 28606603 |
| Title : Human arylacetamide deacetylase hydrolyzes ketoconazole to trigger hepatocellular toxicity - Fukami_2016_Biochem.Pharmacol_116_153 |
| Author(s) : Fukami T , Iida A , Konishi K , Nakajima M |
| Ref : Biochemical Pharmacology , 116 :153 , 2016 |
| Abstract : |
| PubMedSearch : Fukami_2016_Biochem.Pharmacol_116_153 |
| PubMedID: 27422753 |
| Title : Arylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and Dog - Kurokawa_2016_Drug.Metab.Dispos_44_409 |
| Author(s) : Kurokawa T , Fukami T , Yoshida T , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 44 :409 , 2016 |
| Abstract : |
| PubMedSearch : Kurokawa_2016_Drug.Metab.Dispos_44_409 |
| PubMedID: 26718653 |
| Title : A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production - Muta_2015_Biochem.Pharmacol_98_659 |
| Author(s) : Muta K , Fukami T , Nakajima M |
| Ref : Biochemical Pharmacology , 98 :659 , 2015 |
| Abstract : |
| PubMedSearch : Muta_2015_Biochem.Pharmacol_98_659 |
| PubMedID: 26408002 |
| Title : Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases - Fukami_2015_Eur.J.Pharm.Sci_78_47 |
| Author(s) : Fukami T , Kariya M , Kurokawa T , Iida A , Nakajima M |
| Ref : Eur J Pharm Sci , 78 :47 , 2015 |
| Abstract : |
| PubMedSearch : Fukami_2015_Eur.J.Pharm.Sci_78_47 |
| PubMedID: 26164127 |
| Gene_locus related to this paper: human-AADAC , human-CES1 , human-CES2 |
| Title : Role of Human Orphan Esterases in Drug-induced Toxicity - Fukami_2015_Yakugaku.Zasshi_135_1235 |
| Author(s) : Fukami T |
| Ref : Yakugaku Zasshi , 135 :1235 , 2015 |
| Abstract : |
| PubMedSearch : Fukami_2015_Yakugaku.Zasshi_135_1235 |
| PubMedID: 26521872 |
| Gene_locus related to this paper: human-ABHD10 |
| Title : A comprehensive review of UDP-glucuronosyltransferase and esterases for drug development - Oda_2015_Drug.Metab.Pharmacokinet_30_30 |
| Author(s) : Oda S , Fukami T , Yokoi T , Nakajima M |
| Ref : Drug Metab Pharmacokinet , 30 :30 , 2015 |
| Abstract : |
| PubMedSearch : Oda_2015_Drug.Metab.Pharmacokinet_30_30 |
| PubMedID: 25760529 |
| Title : Characterization of Species Differences in Tissue Diltiazem Deacetylation Identifies Ces2a as a Rat-Specific Diltiazem Deacetylase - Kurokawa_2015_Drug.Metab.Dispos_43_1218 |
| Author(s) : Kurokawa T , Fukami T , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 43 :1218 , 2015 |
| Abstract : |
| PubMedSearch : Kurokawa_2015_Drug.Metab.Dispos_43_1218 |
| PubMedID: 25979260 |
| Title : P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice - Tang_2015_Mol.Pharm_12_3714 |
| Author(s) : Tang SC , Kort A , Cheung KL , Rosing H , Fukami T , Durmus S , Wagenaar E , Hendrikx JJ , Nakajima M , van Vlijmen BJ , Beijnen JH , Schinkel AH |
| Ref : Mol Pharm , 12 :3714 , 2015 |
| Abstract : |
| PubMedSearch : Tang_2015_Mol.Pharm_12_3714 |
| PubMedID: 26317243 |
| Title : An Orphan Esterase ABHD10 Modulates Probenecid Acyl Glucuronidation in Human Liver - Ito_2014_Drug.Metab.Dispos_42_2109 |
| Author(s) : Ito Y , Fukami T , Yokoi T , Nakajima M |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :2109 , 2014 |
| Abstract : |
| PubMedSearch : Ito_2014_Drug.Metab.Dispos_42_2109 |
| PubMedID: 25217485 |
| Gene_locus related to this paper: human-ABHD10 , mouse-abhda |
| Title : P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice - Tang_2014_Clin.Cancer.Res_20_3133 |
| Author(s) : Tang SC , Sparidans RW , Cheung KL , Fukami T , Durmus S , Wagenaar E , Yokoi T , van Vlijmen BJ , Beijnen JH , Schinkel AH |
| Ref : Clin Cancer Research , 20 :3133 , 2014 |
| Abstract : |
| PubMedSearch : Tang_2014_Clin.Cancer.Res_20_3133 |
| PubMedID: 24727322 |
| Title : Indiplon is hydrolyzed by arylacetamide deacetylase in human liver - Shimizu_2014_Drug.Metab.Dispos_42_751 |
| Author(s) : Shimizu M , Fukami T , Ito Y , Kurokawa T , Kariya M , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :751 , 2014 |
| Abstract : |
| PubMedSearch : Shimizu_2014_Drug.Metab.Dispos_42_751 |
| PubMedID: 24464802 |
| Title : Screening of specific inhibitors for human carboxylesterases or arylacetamide deacetylase - Shimizu_2014_Drug.Metab.Dispos_42_1103 |
| Author(s) : Shimizu M , Fukami T , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :1103 , 2014 |
| Abstract : |
| PubMedSearch : Shimizu_2014_Drug.Metab.Dispos_42_1103 |
| PubMedID: 24751575 |
| Gene_locus related to this paper: human-AADAC , human-CES1 , human-CES2 |
| Title : N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity - Muta_2014_Biochem.Pharmacol_87_352 |
| Author(s) : Muta K , Fukami T , Nakajima M , Yokoi T |
| Ref : Biochemical Pharmacology , 87 :352 , 2014 |
| Abstract : |
| PubMedSearch : Muta_2014_Biochem.Pharmacol_87_352 |
| PubMedID: 24125761 |
| Gene_locus related to this paper: human-AADAC |
| Title : Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation - Higuchi_2013_Drug.Metab.Dispos_41_1220 |
| Author(s) : Higuchi R , Fukami T , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 41 :1220 , 2013 |
| Abstract : |
| PubMedSearch : Higuchi_2013_Drug.Metab.Dispos_41_1220 |
| PubMedID: 23530020 |
| Title : Human alpha\/beta hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver - Iwamura_2012_J.Biol.Chem_287_9240 |
| Author(s) : Iwamura A , Fukami T , Higuchi R , Nakajima M , Yokoi T |
| Ref : Journal of Biological Chemistry , 287 :9240 , 2012 |
| Abstract : |
| PubMedSearch : Iwamura_2012_J.Biol.Chem_287_9240 |
| PubMedID: 22294686 |
| Gene_locus related to this paper: human-ABHD10 , mouse-abhda |
| Title : The emerging role of human esterases - Fukami_2012_Drug.Metab.Pharmacokinet_27_466 |
| Author(s) : Fukami T , Yokoi T |
| Ref : Drug Metab Pharmacokinet , 27 :466 , 2012 |
| Abstract : |
| PubMedSearch : Fukami_2012_Drug.Metab.Pharmacokinet_27_466 |
| PubMedID: 22813719 |
| Gene_locus related to this paper: human-ABHD10 |
| Title : Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver - Kobayashi_2012_Drug.Metab.Dispos_40_1080 |
| Author(s) : Kobayashi Y , Fukami T , Shimizu M , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 40 :1080 , 2012 |
| Abstract : |
| PubMedSearch : Kobayashi_2012_Drug.Metab.Dispos_40_1080 |
| PubMedID: 22446520 |
| Title : Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse - Kobayashi_2012_Drug.Metab.Dispos_40_671 |
| Author(s) : Kobayashi Y , Fukami T , Nakajima A , Watanabe A , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 40 :671 , 2012 |
| Abstract : |
| PubMedSearch : Kobayashi_2012_Drug.Metab.Dispos_40_671 |
| PubMedID: 22207054 |
| Gene_locus related to this paper: human-AADAC , mouse-aryla , ratno-aryla |
| Title : A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity - Shimizu_2012_Drug.Metab.Dispos_40_1183 |
| Author(s) : Shimizu M , Fukami T , Kobayashi Y , Takamiya M , Aoki Y , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 40 :1183 , 2012 |
| Abstract : |
| PubMedSearch : Shimizu_2012_Drug.Metab.Dispos_40_1183 |
| PubMedID: 22415931 |
| Gene_locus related to this paper: human-AADAC |
| Title : Human arylacetamide deacetylase is responsible for deacetylation of rifamycins: rifampicin, rifabutin, and rifapentine - Nakajima_2011_Biochem.Pharmacol_82_1747 |
| Author(s) : Nakajima A , Fukami T , Kobayashi Y , Watanabe A , Nakajima M , Yokoi T |
| Ref : Biochemical Pharmacology , 82 :1747 , 2011 |
| Abstract : |
| PubMedSearch : Nakajima_2011_Biochem.Pharmacol_82_1747 |
| PubMedID: 21856291 |
| Gene_locus related to this paper: human-AADAC |
| Title : In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities - Fukami_2010_Drug.Metab.Dispos_38_2173 |
| Author(s) : Fukami T , Takahashi S , Nakagawa N , Maruichi T , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 38 :2173 , 2010 |
| Abstract : |
| PubMedSearch : Fukami_2010_Drug.Metab.Dispos_38_2173 |
| PubMedID: 20810539 |
| Title : Arylacetamide deacetylase is a determinant enzyme for the difference in hydrolase activities of phenacetin and acetaminophen - Watanabe_2010_Drug.Metab.Dispos_38_1532 |
| Author(s) : Watanabe A , Fukami T , Takahashi S , Kobayashi Y , Nakagawa N , Nakajima M , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 38 :1532 , 2010 |
| Abstract : |
| PubMedSearch : Watanabe_2010_Drug.Metab.Dispos_38_1532 |
| PubMedID: 20542992 |
| Title : Transcriptional regulation of human carboxylesterase 1A1 by nuclear factor-erythroid 2 related factor 2 (Nrf2) - Maruichi_2010_Biochem.Pharmacol_79_288 |
| Author(s) : Maruichi T , Fukami T , Nakajima M , Yokoi T |
| Ref : Biochemical Pharmacology , 79 :288 , 2010 |
| Abstract : |
| PubMedSearch : Maruichi_2010_Biochem.Pharmacol_79_288 |
| PubMedID: 19715681 |
| Gene_locus related to this paper: human-CES1 |
| Title : Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis - Watanabe_2009_Drug.Metab.Dispos_37_1513 |
| Author(s) : Watanabe A , Fukami T , Nakajima M , Takamiya M , Aoki Y , Yokoi T |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 37 :1513 , 2009 |
| Abstract : |
| PubMedSearch : Watanabe_2009_Drug.Metab.Dispos_37_1513 |
| PubMedID: 19339378 |
| Gene_locus related to this paper: human-AADAC |
| Title : Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes - Fukami_2008_Pharmacogenet.Genomics_18_911 |
| Author(s) : Fukami T , Nakajima M , Maruichi T , Takahashi S , Takamiya M , Aoki Y , McLeod HL , Yokoi T |
| Ref : Pharmacogenet Genomics , 18 :911 , 2008 |
| Abstract : |
| PubMedSearch : Fukami_2008_Pharmacogenet.Genomics_18_911 |
| PubMedID: 18794728 |
| Gene_locus related to this paper: human-CES1 |