Mycophenolate-mofetil
General
Type : Pro-Drug || Drug || Not A\/B H target || Morpholine || Benzofuran
Chemical_Nomenclature : 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
Canonical SMILES : CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)OCCN3CCOCC3)O
InChI : InChI=1S\/C23H31NO7\/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3\/h4,26H,5-14H2,1-3H3\/b15-4+
InChIKey : RTGDFNSFWBGLEC-SYZQJQIISA-N
Other name(s) : mycophenolate mofetil, CellCept, 115007-34-6, Myfenax, MMF, CHEBI:8764, SCHEMBL4195, CHEMBL1456, SCHEMBL218782, CHEBI:93612
Target
Families : Carb_B_Chordata
References (2)
| Title : Difference in substrate specificity of carboxylesterase and arylacetamide deacetylase between dogs and humans - Yoshida_2018_Eur.J.Pharm.Sci_111_167 |
| Author(s) : Yoshida T , Fukami T , Kurokawa T , Gotoh S , Oda A , Nakajima M |
| Ref : Eur J Pharm Sci , 111 :167 , 2018 |
| Abstract : Yoshida_2018_Eur.J.Pharm.Sci_111_167 |
| ESTHER : Yoshida_2018_Eur.J.Pharm.Sci_111_167 |
| PubMedSearch : Yoshida_2018_Eur.J.Pharm.Sci_111_167 |
| PubMedID: 28966098 |
| Gene_locus related to this paper: canfa-CESDD1 , canfa-f1p6w8 , canlf-e2r2h2 |
| Title : Involvement of carboxylesterase 1 and 2 in the hydrolysis of mycophenolate mofetil - Fujiyama_2010_Drug.Metab.Dispos_38_2210 |
| Author(s) : Fujiyama N , Miura M , Kato S , Sone T , Isobe M , Satoh S |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 38 :2210 , 2010 |
| Abstract : Fujiyama_2010_Drug.Metab.Dispos_38_2210 |
| ESTHER : Fujiyama_2010_Drug.Metab.Dispos_38_2210 |
| PubMedSearch : Fujiyama_2010_Drug.Metab.Dispos_38_2210 |
| PubMedID: 20823294 |