stahy-lipas
Staphylococcus hyicus gene for lipase SHyL
Comment
Rosenstein R, Gotz F a review on Staphylococcal lipases. There is a long precursor which is cut to a 46kDa active form
Relationship
Family : Bacterial_lip_FamI.6
Block : L
Position in NCBI Life Tree : Staphylococcus hyicus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Staphylococcaceae N E > Staphylococcus N E > Staphylococcus hyicus N EMolecular evidence
No mutation
No kinetic
No disease
No substrate
Sequence
Peptide
MARIRARGSS RVDVPKENTT AQNKFTSQAS DKKPTVKAAP EAVQNPENPK NKDPFVFVHG FTGFVGEVAA KGENYWGGTK ANLRNHLRKA GYETYEASVS ALASNHERAV ELYYYLKGGR VDYGAAHSEK YGHERYGKTY EGVLKDWKPG HPVHFIGHSM GGQTIRLLEH YLRFGDKAEI AYQQQHGGII SELFKGGQDN MVTSITTIAT PHNGTHASDD IGNTPTIRNI LYSFAQMSSH LGTIDFGMDH WGFKRKDGES LTDYNKRIAE SKIWDSEDTG LYDLTREGAE KINQKTELNP NIYYKTYTGV ATHETQLGKH IADLGMEFTK ILTGNYIGSV DDILWRPNDG LVSEISSQHP SDEKNISVDE NSELHKGTWQ VMPTMKGWDH SDFIGNDALD TKHSAIELTN FYHSISDYLM RIEKAESTKN A
References (18)
| Title : Contributions of the pre- and pro-regions of a Staphylococcus hyicus lipase to secretion of a heterologous protein by Bacillus subtilis - Kouwen_2010_Appl.Environ.Microbiol_76_659 |
| Author(s) : Kouwen TR , Nielsen AK , Denham EL , Dubois JY , Dorenbos R , Rasmussen MD , Quax WJ , Freudl R , van Dijl JM |
| Ref : Applied Environmental Microbiology , 76 :659 , 2010 |
| PubMedID: 19948853 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Structural basis of phospholipase activity of Staphylococcus hyicus lipase - Tiesinga_2007_J.Mol.Biol_371_447 |
| Author(s) : Tiesinga JJ , van Pouderoyen G , Nardini M , Ransac S , Dijkstra BW |
| Ref : Journal of Molecular Biology , 371 :447 , 2007 |
| PubMedID: 17582438 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Expression of the Staphylococcus hyicus lipase in Lactococcus lactis - Drouault_2000_Appl.Environ.Microbiol_66_588 |
| Author(s) : Drouault S , Corthier G , Ehrlich SD , Renault P |
| Ref : Applied Environmental Microbiology , 66 :588 , 2000 |
| PubMedID: 10653722 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Staphylococcal lipases: biochemical and molecular characterization - Rosenstein_2000_Biochimie_82_1005 |
| Author(s) : Rosenstein R , Gotz F |
| Ref : Biochimie , 82 :1005 , 2000 |
| PubMedID: 11099797 |
| Gene_locus related to this paper: staau-LIP , staau-lipas , staep-lipas , staep-SE0245 , stahy-lipas , stawa-GEHA , staxy-gehH , staxy-q2tpv1 |
| Title : Identification of a calcium binding site in Staphylococcus hyicus lipase: generation of calcium-independent variants - Simons_1999_Biochemistry_38_2 |
| Author(s) : Simons JW , van Kampen MD , Ubarretxena-Belandia I , Cox RC , Alves dos Santos CM , Egmond MR , Verheij HM |
| Ref : Biochemistry , 38 :2 , 1999 |
| PubMedID: 9890877 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Substrate specificity of Staphylococcus hyicus lipase and Staphylococcus aureus lipase as studied by in vivo chimeragenesis - van Kampen_1998_Biochemistry_37_3459 |
| Author(s) : van Kampen MD , Dekker N , Egmond MR , Verheij HM |
| Ref : Biochemistry , 37 :3459 , 1998 |
| PubMedID: 9521667 |
| Gene_locus related to this paper: stahy-lipas |
| Title : The phospholipase activity of Staphylococcus hyicus lipase strongly depends on a single Ser to Val mutation - van Kampen_1998_Chem.Phys.Lipids_93_39 |
| Author(s) : van Kampen MD , Simons JW , Dekker N , Egmond MR , Verheij HM |
| Ref : Chemistry & Physic of Lipids , 93 :39 , 1998 |
| PubMedID: 9720248 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Staphylococcal lipases: molecular characterisation, secretion, and processing - Gotz_1998_Chem.Phys.Lipids_93_15 |
| Author(s) : Gotz F , Verheij HM , Rosenstein R |
| Ref : Chemistry & Physic of Lipids , 93 :15 , 1998 |
| PubMedID: 9720246 |
| Gene_locus related to this paper: staau-LIP , staau-lipas , staep-lipas , staep-SE0245 , stahy-lipas , stawa-GEHA , staxy-gehH |
| Title : Use of the pre-pro part of Staphylococcus hyicus lipase as a carrier for secretion of Escherichia coli outer membrane protein A (OmpA) prevents proteolytic degradation of OmpA by cell-associated protease(s) in two different gram-positive bacteria - Meens_1997_Appl.Environ.Microbiol_63_2814 |
| Author(s) : Meens J , Herbort M , Klein M , Freudl R |
| Ref : Applied Environmental Microbiology , 63 :2814 , 1997 |
| PubMedID: 9212429 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Facile purification of highly active recombinant Staphylococcus hyicus lipase fragment and characterization of a putative lid region - Chang_1996_Biochem.Biophys.Res.Commun_228_774 |
| Author(s) : Chang RC , Chen JC , Shaw JF |
| Ref : Biochemical & Biophysical Research Communications , 228 :774 , 1996 |
| PubMedID: 8941352 |
| Gene_locus related to this paper: stahy-lipas |
| Title : The lipase from Staphylococcus aureus. Expression in Escherichia coli, large-scale purification and comparison of substrate specificity to Staphylococcus hyicus lipase - Simons_1996_Eur.J.Biochem_242_760 |
| Author(s) : Simons JW , Adams H , Cox RC , Dekker N , Gotz F , Slotboom AJ , Verheij HM |
| Ref : European Journal of Biochemistry , 242 :760 , 1996 |
| PubMedID: 9022707 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Identification of the active site histidine in Staphylococcus hyicus lipase using chemical modification and mass spectrometry - Boots_1995_Biochim.Biophys.Acta_1248_27 |
| Author(s) : Boots JW , van Dongen WD , Verheij HM , De Haas GH , Haverkamp J , Slotboom AJ |
| Ref : Biochimica & Biophysica Acta , 1248 :27 , 1995 |
| PubMedID: 7711054 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Comparative biochemical and molecular analysis of the Staphylococcus hyicus, Staphylococcus aureus and a hybrid lipase. Indication for a C-terminal phospholipase domain - Nikoleit_1995_Eur.J.Biochem_228_732 |
| Author(s) : Nikoleit K , Rosenstein R , Verheij HM , Gotz F |
| Ref : European Journal of Biochemistry , 228 :732 , 1995 |
| PubMedID: 7737171 |
| Gene_locus related to this paper: staau-LIP , stahy-lipas |
| Title : Phosphonate analogues of triacylglycerols are potent inhibitors of lipase - Mannesse_1995_Biochim.Biophys.Acta_1259_56 |
| Author(s) : Mannesse ML , Boots JW , Dijkman R , Slotboom AJ , van der Hijden HT , Egmond MR , Verheij HM , De Haas GH |
| Ref : Biochimica & Biophysica Acta , 1259 :56 , 1995 |
| PubMedID: 7492616 |
| Gene_locus related to this paper: fusso-cutas , stahy-lipas |
| Title : Evidence for importance of the Staphylococcus hyicus lipase pro-peptide in lipase secretion, stability and activity - Demleitner_1994_FEMS.Microbiol.Lett_121_189 |
| Author(s) : Demleitner G , Gotz F |
| Ref : FEMS Microbiology Letters , 121 :189 , 1994 |
| PubMedID: 7926670 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Inactivation of Staphylococcus hyicus lipase by hexadecylsulfonyl fluoride: evidence for an active site serine - Leuveling_1994_Protein.Eng_7_579 |
| Author(s) : Leuveling Tjeenk M , Bulsink YB , Slotboom AJ , Verheij HM , De Haas GH , Demleitner G , Gotz F |
| Ref : Protein Engineering , 7 :579 , 1994 |
| PubMedID: 8029215 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Purification and substrate specificity of Staphylococcus hyicus lipase - van Oort_1989_Biochemistry_28_9278 |
| Author(s) : van Oort MG , Deveer AM , Dijkman R , Tjeenk ML , Verheij HM , De Haas GH , Wenzig E , Gotz F |
| Ref : Biochemistry , 28 :9278 , 1989 |
| PubMedID: 2611229 |
| Gene_locus related to this paper: stahy-lipas |
| Title : Complete nucleotide sequence of the lipase gene from Staphylococcus hyicus cloned in Staphylococcus carnosus - Gotz_1985_Nucleic.Acids.Res_13_5895 |
| Author(s) : Gotz F , Popp F , Korn E , Schleifer KH |
| Ref : Nucleic Acids Research , 13 :5895 , 1985 |
| PubMedID: 2994017 |
| Gene_locus related to this paper: stahy-lipas |