stahy-lipas

Staphylococcus hyicus gene for lipase SHyL

Comment

Rosenstein R, Gotz F a review on Staphylococcal lipases. There is a long precursor which is cut to a 46kDa active form

Relationship

Family : Bacterial_lip_FamI.6

Block : L

Position in NCBI Life Tree : Staphylococcus hyicus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Staphylococcaceae N E > Staphylococcus N E > Staphylococcus hyicus N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

Database

Sequence

Peptide

MARIRARGSS RVDVPKENTT AQNKFTSQAS DKKPTVKAAP EAVQNPENPK NKDPFVFVHG FTGFVGEVAA KGENYWGGTK ANLRNHLRKA GYETYEASVS ALASNHERAV ELYYYLKGGR VDYGAAHSEK YGHERYGKTY EGVLKDWKPG HPVHFIGHSM GGQTIRLLEH YLRFGDKAEI AYQQQHGGII SELFKGGQDN MVTSITTIAT PHNGTHASDD IGNTPTIRNI LYSFAQMSSH LGTIDFGMDH WGFKRKDGES LTDYNKRIAE SKIWDSEDTG LYDLTREGAE KINQKTELNP NIYYKTYTGV ATHETQLGKH IADLGMEFTK ILTGNYIGSV DDILWRPNDG LVSEISSQHP SDEKNISVDE NSELHKGTWQ VMPTMKGWDH SDFIGNDALD TKHSAIELTN FYHSISDYLM RIEKAESTKN A

References (18)

Title : Contributions of the pre- and pro-regions of a Staphylococcus hyicus lipase to secretion of a heterologous protein by Bacillus subtilis - Kouwen_2010_Appl.Environ.Microbiol_76_659
Author(s) : Kouwen TR , Nielsen AK , Denham EL , Dubois JY , Dorenbos R , Rasmussen MD , Quax WJ , Freudl R , van Dijl JM
Ref : Applied Environmental Microbiology , 76 :659 , 2010
Abstract :
PubMedSearch : Kouwen_2010_Appl.Environ.Microbiol_76_659
PubMedID: 19948853
Gene_locus related to this paper: stahy-lipas

Title : Structural basis of phospholipase activity of Staphylococcus hyicus lipase - Tiesinga_2007_J.Mol.Biol_371_447
Author(s) : Tiesinga JJ , van Pouderoyen G , Nardini M , Ransac S , Dijkstra BW
Ref : Journal of Molecular Biology , 371 :447 , 2007
Abstract :
PubMedSearch : Tiesinga_2007_J.Mol.Biol_371_447
PubMedID: 17582438
Gene_locus related to this paper: stahy-lipas

Title : Expression of the Staphylococcus hyicus lipase in Lactococcus lactis - Drouault_2000_Appl.Environ.Microbiol_66_588
Author(s) : Drouault S , Corthier G , Ehrlich SD , Renault P
Ref : Applied Environmental Microbiology , 66 :588 , 2000
Abstract :
PubMedSearch : Drouault_2000_Appl.Environ.Microbiol_66_588
PubMedID: 10653722
Gene_locus related to this paper: stahy-lipas

Title : Staphylococcal lipases: biochemical and molecular characterization - Rosenstein_2000_Biochimie_82_1005
Author(s) : Rosenstein R , Gotz F
Ref : Biochimie , 82 :1005 , 2000
Abstract :
PubMedSearch : Rosenstein_2000_Biochimie_82_1005
PubMedID: 11099797
Gene_locus related to this paper: staau-LIP , staau-lipas , staep-lipas , staep-SE0245 , stahy-lipas , stawa-GEHA , staxy-gehH , staxy-q2tpv1

Title : Identification of a calcium binding site in Staphylococcus hyicus lipase: generation of calcium-independent variants - Simons_1999_Biochemistry_38_2
Author(s) : Simons JW , van Kampen MD , Ubarretxena-Belandia I , Cox RC , Alves dos Santos CM , Egmond MR , Verheij HM
Ref : Biochemistry , 38 :2 , 1999
Abstract :
PubMedSearch : Simons_1999_Biochemistry_38_2
PubMedID: 9890877
Gene_locus related to this paper: stahy-lipas

Title : Substrate specificity of Staphylococcus hyicus lipase and Staphylococcus aureus lipase as studied by in vivo chimeragenesis - van Kampen_1998_Biochemistry_37_3459
Author(s) : van Kampen MD , Dekker N , Egmond MR , Verheij HM
Ref : Biochemistry , 37 :3459 , 1998
Abstract :
PubMedSearch : van Kampen_1998_Biochemistry_37_3459
PubMedID: 9521667
Gene_locus related to this paper: stahy-lipas

Title : The phospholipase activity of Staphylococcus hyicus lipase strongly depends on a single Ser to Val mutation - van Kampen_1998_Chem.Phys.Lipids_93_39
Author(s) : van Kampen MD , Simons JW , Dekker N , Egmond MR , Verheij HM
Ref : Chemistry & Physic of Lipids , 93 :39 , 1998
Abstract :
PubMedSearch : van Kampen_1998_Chem.Phys.Lipids_93_39
PubMedID: 9720248
Gene_locus related to this paper: stahy-lipas

Title : Staphylococcal lipases: molecular characterisation, secretion, and processing - Gotz_1998_Chem.Phys.Lipids_93_15
Author(s) : Gotz F , Verheij HM , Rosenstein R
Ref : Chemistry & Physic of Lipids , 93 :15 , 1998
Abstract :
PubMedSearch : Gotz_1998_Chem.Phys.Lipids_93_15
PubMedID: 9720246
Gene_locus related to this paper: staau-LIP , staau-lipas , staep-lipas , staep-SE0245 , stahy-lipas , stawa-GEHA , staxy-gehH

Title : Use of the pre-pro part of Staphylococcus hyicus lipase as a carrier for secretion of Escherichia coli outer membrane protein A (OmpA) prevents proteolytic degradation of OmpA by cell-associated protease(s) in two different gram-positive bacteria - Meens_1997_Appl.Environ.Microbiol_63_2814
Author(s) : Meens J , Herbort M , Klein M , Freudl R
Ref : Applied Environmental Microbiology , 63 :2814 , 1997
Abstract :
PubMedSearch : Meens_1997_Appl.Environ.Microbiol_63_2814
PubMedID: 9212429
Gene_locus related to this paper: stahy-lipas

Title : Facile purification of highly active recombinant Staphylococcus hyicus lipase fragment and characterization of a putative lid region - Chang_1996_Biochem.Biophys.Res.Commun_228_774
Author(s) : Chang RC , Chen JC , Shaw JF
Ref : Biochemical & Biophysical Research Communications , 228 :774 , 1996
Abstract :
PubMedSearch : Chang_1996_Biochem.Biophys.Res.Commun_228_774
PubMedID: 8941352
Gene_locus related to this paper: stahy-lipas

Title : The lipase from Staphylococcus aureus. Expression in Escherichia coli, large-scale purification and comparison of substrate specificity to Staphylococcus hyicus lipase - Simons_1996_Eur.J.Biochem_242_760
Author(s) : Simons JW , Adams H , Cox RC , Dekker N , Gotz F , Slotboom AJ , Verheij HM
Ref : European Journal of Biochemistry , 242 :760 , 1996
Abstract :
PubMedSearch : Simons_1996_Eur.J.Biochem_242_760
PubMedID: 9022707
Gene_locus related to this paper: stahy-lipas

Title : Phosphonate analogues of triacylglycerols are potent inhibitors of lipase - Mannesse_1995_Biochim.Biophys.Acta_1259_56
Author(s) : Mannesse ML , Boots JW , Dijkman R , Slotboom AJ , van der Hijden HT , Egmond MR , Verheij HM , De Haas GH
Ref : Biochimica & Biophysica Acta , 1259 :56 , 1995
Abstract :
PubMedSearch : Mannesse_1995_Biochim.Biophys.Acta_1259_56
PubMedID: 7492616
Gene_locus related to this paper: fusso-cutas , stahy-lipas

Title : Identification of the active site histidine in Staphylococcus hyicus lipase using chemical modification and mass spectrometry - Boots_1995_Biochim.Biophys.Acta_1248_27
Author(s) : Boots JW , van Dongen WD , Verheij HM , De Haas GH , Haverkamp J , Slotboom AJ
Ref : Biochimica & Biophysica Acta , 1248 :27 , 1995
Abstract :
PubMedSearch : Boots_1995_Biochim.Biophys.Acta_1248_27
PubMedID: 7711054
Gene_locus related to this paper: stahy-lipas

Title : Comparative biochemical and molecular analysis of the Staphylococcus hyicus, Staphylococcus aureus and a hybrid lipase. Indication for a C-terminal phospholipase domain - Nikoleit_1995_Eur.J.Biochem_228_732
Author(s) : Nikoleit K , Rosenstein R , Verheij HM , Gotz F
Ref : European Journal of Biochemistry , 228 :732 , 1995
Abstract :
PubMedSearch : Nikoleit_1995_Eur.J.Biochem_228_732
PubMedID: 7737171
Gene_locus related to this paper: staau-LIP , stahy-lipas

Title : Evidence for importance of the Staphylococcus hyicus lipase pro-peptide in lipase secretion, stability and activity - Demleitner_1994_FEMS.Microbiol.Lett_121_189
Author(s) : Demleitner G , Gotz F
Ref : FEMS Microbiology Letters , 121 :189 , 1994
Abstract :
PubMedSearch : Demleitner_1994_FEMS.Microbiol.Lett_121_189
PubMedID: 7926670
Gene_locus related to this paper: stahy-lipas

Title : Inactivation of Staphylococcus hyicus lipase by hexadecylsulfonyl fluoride: evidence for an active site serine - Leuveling_1994_Protein.Eng_7_579
Author(s) : Leuveling Tjeenk M , Bulsink YB , Slotboom AJ , Verheij HM , De Haas GH , Demleitner G , Gotz F
Ref : Protein Engineering , 7 :579 , 1994
Abstract :
PubMedSearch : Leuveling_1994_Protein.Eng_7_579
PubMedID: 8029215
Gene_locus related to this paper: stahy-lipas

Title : Purification and substrate specificity of Staphylococcus hyicus lipase - van Oort_1989_Biochemistry_28_9278
Author(s) : van Oort MG , Deveer AM , Dijkman R , Tjeenk ML , Verheij HM , De Haas GH , Wenzig E , Gotz F
Ref : Biochemistry , 28 :9278 , 1989
Abstract :
PubMedSearch : van Oort_1989_Biochemistry_28_9278
PubMedID: 2611229
Gene_locus related to this paper: stahy-lipas

Title : Complete nucleotide sequence of the lipase gene from Staphylococcus hyicus cloned in Staphylococcus carnosus - Gotz_1985_Nucleic.Acids.Res_13_5895
Author(s) : Gotz F , Popp F , Korn E , Schleifer KH
Ref : Nucleic Acids Research , 13 :5895 , 1985
Abstract :
PubMedSearch : Gotz_1985_Nucleic.Acids.Res_13_5895
PubMedID: 2994017
Gene_locus related to this paper: stahy-lipas