staau-LIP

Staphylococcus aureus (lipase) (triglyceride lipase)(EC 3.1.1.3) (tributyrase) SAL-1 sal1 geh

Comment

Rosenstein R, Gotz F a review on Staphylococcal lipases. There is a long precursor which is cut to a 46kDa active form. There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains

Relationship

Family : Bacterial_lip_FamI.6

Block : L

Position in NCBI Life Tree : Staphylococcus aureus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Staphylococcaceae N E > Staphylococcus N E > Staphylococcus aureus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

TLPNKGTKEL TAKAKDDQTN KVAKQGQYKN QDPIVLVHGF NGFTDDINPS VLAHYWGGNK MNIRQDLEEN GYKAYEASIS AFGSNYDRAV ELYYYIKGGR VDYGAAHAAK YGHERYGKTY EGIYKDWKPG QKVHLVGHSM GGQTIRQLEE LLRNGNREEI EYQKKHGGEI SPLFKGNHDN MISSITTTLG TPHNGTHASD LAGNEALVRQ IVFDIGKMFG NKNSRVDFGL AQWGLKQKPN ESYIDYVKRV KQSNLWKSKD NGFYDLTREG ATDLNRKTSL NPNIVYKTYT GEATHKALNS DRQKADLNMF FPFVITGNLI GKATEKEWRE NDGLVSVISS QHPFNQAYTK ATDKIQKGIW QVTPTKHDWD HVDFVGQDSS DTVRTREELQ DFWHHLADDL VKTEKLTDTK QA

References (20)

Title : Bacterial lipolysis of immune-activating ligands promotes evasion of innate defenses - Chen_2019_Proc.Natl.Acad.Sci.U.S.A_116_3764
Author(s) : Chen X , Alonzo F, 3rd
Ref : Proc Natl Acad Sci U S A , 116 :3764 , 2019
Abstract :
PubMedSearch : Chen_2019_Proc.Natl.Acad.Sci.U.S.A_116_3764
PubMedID: 30755523
Gene_locus related to this paper: staau-LIP , staau-lipas

Title : Staphylococcal (phospho)lipases promote biofilm formation and host cell invasion - Nguyen_2018_Int.J.Med.Microbiol_308_653
Author(s) : Nguyen MT , Luqman A , Bitschar K , Hertlein T , Dick J , Ohlsen K , Broker B , Schittek B , Gotz F
Ref : Int J Med Microbiol , 308 :653 , 2018
Abstract :
PubMedSearch : Nguyen_2018_Int.J.Med.Microbiol_308_653
PubMedID: 29203111
Gene_locus related to this paper: staau-LIP , staau-lipas , stawa-GEHA

Title : Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis - Schijffelen_2010_BMC.Genomics_11_376
Author(s) : Schijffelen MJ , Boel CH , van Strijp JA , Fluit AC
Ref : BMC Genomics , 11 :376 , 2010
Abstract :
PubMedSearch : Schijffelen_2010_BMC.Genomics_11_376
PubMedID: 20546576
Gene_locus related to this paper: staau-c8mfq3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Complete genome sequence of Staphylococcus aureus strain JKD6159, a unique Australian clone of ST93-IV community methicillin-resistant Staphylococcus aureus - Chua_2010_J.Bacteriol_192_5556
Author(s) : Chua K , Seemann T , Harrison PF , Davies JK , Coutts SJ , Chen H , Haring V , Moore R , Howden BP , Stinear TP
Ref : Journal of Bacteriology , 192 :5556 , 2010
Abstract :
PubMedSearch : Chua_2010_J.Bacteriol_192_5556
PubMedID: 20729356
Gene_locus related to this paper: staau-c8mfq3 , staau-d2feb3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2422 , staau-SAV0321 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Evolutionary genomics of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation - Guinane_2010_Genome.Biol.Evol_2_454
Author(s) : Guinane CM , Ben Zakour NL , Tormo-Mas MA , Weinert LA , Lowder BV , Cartwright RA , Smyth DS , Smyth CJ , Lindsay JA , Gould KA , Witney A , Hinds J , Bollback JP , Rambaut A , Penades JR , Fitzgerald JR
Ref : Genome Biol Evol , 2 :454 , 2010
Abstract :
PubMedSearch : Guinane_2010_Genome.Biol.Evol_2_454
PubMedID: 20624747
Gene_locus related to this paper: staau-d2feb3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW) - Holden_2010_J.Bacteriol_192_888
Author(s) : Holden MT , Lindsay JA , Corton C , Quail MA , Cockfield JD , Pathak S , Batra R , Parkhill J , Bentley SD , Edgeworth JD
Ref : Journal of Bacteriology , 192 :888 , 2010
Abstract :
PubMedSearch : Holden_2010_J.Bacteriol_192_888
PubMedID: 19948800
Gene_locus related to this paper: staau-LIP , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus - Lowder_2009_Proc.Natl.Acad.Sci.U.S.A_106_19545
Author(s) : Lowder BV , Guinane CM , Ben Zakour NL , Weinert LA , Conway-Morris A , Cartwright RA , Simpson AJ , Rambaut A , Nubel U , Fitzgerald JR
Ref : Proc Natl Acad Sci U S A , 106 :19545 , 2009
Abstract :
PubMedSearch : Lowder_2009_Proc.Natl.Acad.Sci.U.S.A_106_19545
PubMedID: 19884497
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance - Neoh_2008_Antimicrob.Agents.Chemother_52_45
Author(s) : Neoh HM , Cui L , Yuzawa H , Takeuchi F , Matsuo M , Hiramatsu K
Ref : Antimicrobial Agents & Chemotherapy , 52 :45 , 2008
Abstract :
PubMedSearch : Neoh_2008_Antimicrob.Agents.Chemother_52_45
PubMedID: 17954695
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands - Baba_2008_J.Bacteriol_190_300
Author(s) : Baba T , Bae T , Schneewind O , Takeuchi F , Hiramatsu K
Ref : Journal of Bacteriology , 190 :300 , 2008
Abstract :
PubMedSearch : Baba_2008_J.Bacteriol_190_300
PubMedID: 17951380
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus - Highlander_2007_BMC.Microbiol_7_99
Author(s) : Highlander SK , Hulten KG , Qin X , Jiang H , Yerrapragada S , Mason EO, Jr. , Shang Y , Williams TM , Fortunov RM , Liu Y , Igboeli O , Petrosino J , Tirumalai M , Uzman A , Fox GE , Cardenas AM , Muzny DM , Hemphill L , Ding Y , Dugan S , Blyth PR , Buhay CJ , Dinh HH , Hawes AC , Holder M , Kovar CL , Lee SL , Liu W , Nazareth LV , Wang Q , Zhou J , Kaplan SL , Weinstock GM
Ref : BMC Microbiol , 7 :99 , 2007
Abstract :
PubMedSearch : Highlander_2007_BMC.Microbiol_7_99
PubMedID: 17986343
Gene_locus related to this paper: staa3-q2fkj0 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Molecular correlates of host specialization in Staphylococcus aureus - Herron-Olson_2007_PLoS.One_2_e1120
Author(s) : Herron-Olson L , Fitzgerald JR , Musser JM , Kapur V
Ref : PLoS ONE , 2 :e1120 , 2007
Abstract :
PubMedSearch : Herron-Olson_2007_PLoS.One_2_e1120
PubMedID: 17971880
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-SAV0321 , staau-SAV0457 , staau-SAV1793

Title : Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus - Diep_2006_Lancet_367_731
Author(s) : Diep BA , Gill SR , Chang RF , Phan TH , Chen JH , Davidson MG , Lin F , Lin J , Carleton HA , Mongodin EF , Sensabaugh GF , Perdreau-Remington F
Ref : Lancet , 367 :731 , 2006
Abstract :
PubMedSearch : Diep_2006_Lancet_367_731
PubMedID: 16517273
Gene_locus related to this paper: staa3-q2fkj0 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain - Gill_2005_J.Bacteriol_187_2426
Author(s) : Gill SR , Fouts DE , Archer GL , Mongodin EF , DeBoy RT , Ravel J , Paulsen IT , Kolonay JF , Brinkac L , Beanan M , Dodson RJ , Daugherty SC , Madupu R , Angiuoli SV , Durkin AS , Haft DH , Vamathevan J , Khouri H , Utterback T , Lee C , Dimitrov G , Jiang L , Qin H , Weidman J , Tran K , Kang K , Hance IR , Nelson KE , Fraser CM
Ref : Journal of Bacteriology , 187 :2426 , 2005
Abstract :
PubMedSearch : Gill_2005_J.Bacteriol_187_2426
PubMedID: 15774886
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594 , staep-lipas , staep-SE0011 , staep-SE0226 , staep-SE0386 , staep-SE0389 , staep-SE0424 , staep-SE0564 , staep-SE0714 , staep-SE0745 , staep-SE0980 , staep-SE1436 , staep-SE1460 , staep-SE1510 , staep-SE1780 , staep-SE1929 , staep-SERP2035 , staep-SE2050 , staep-SE2095 , staep-SE2213 , staep-SE2328

Title : Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance - Holden_2004_Proc.Natl.Acad.Sci.U.S.A_101_9786
Author(s) : Holden MT , Feil EJ , Lindsay JA , Peacock SJ , Day NP , Enright MC , Foster TJ , Moore CE , Hurst L , Atkin R , Barron A , Bason N , Bentley SD , Chillingworth C , Chillingworth T , Churcher C , Clark L , Corton C , Cronin A , Doggett J , Dowd L , Feltwell T , Hance Z , Harris B , Hauser H , Holroyd S , Jagels K , James KD , Lennard N , Line A , Mayes R , Moule S , Mungall K , Ormond D , Quail MA , Rabbinowitsch E , Rutherford K , Sanders M , Sharp S , Simmonds M , Stevens K , Whitehead S , Barrell BG , Spratt BG , Parkhill J
Ref : Proc Natl Acad Sci U S A , 101 :9786 , 2004
Abstract :
PubMedSearch : Holden_2004_Proc.Natl.Acad.Sci.U.S.A_101_9786
PubMedID: 15213324
Gene_locus related to this paper: staau-d2feb3 , staau-d2uin3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2594

Title : Genome and virulence determinants of high virulence community-acquired MRSA - Baba_2002_Lancet_359_1819
Author(s) : Baba T , Takeuchi F , Kuroda M , Yuzawa H , Aoki K , Oguchi A , Nagai Y , Iwama N , Asano K , Naimi T , Kuroda H , Cui L , Yamamoto K , Hiramatsu K
Ref : Lancet , 359 :1819 , 2002
Abstract :
PubMedSearch : Baba_2002_Lancet_359_1819
PubMedID: 12044378
Gene_locus related to this paper: staau-d2uin3 , staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350

Title : Whole genome sequencing of meticillin-resistant Staphylococcus aureus - Kuroda_2001_Lancet_357_1225
Author(s) : Kuroda M , Ohta T , Uchiyama I , Baba T , Yuzawa H , Kobayashi I , Cui L , Oguchi A , Aoki K , Nagai Y , Lian J , Ito T , Kanamori M , Matsumaru H , Maruyama A , Murakami H , Hosoyama A , Mizutani-Ui Y , Takahashi NK , Sawano T , Inoue R , Kaito C , Sekimizu K , Hirakawa H , Kuhara S , Goto S , Yabuzaki J , Kanehisa M , Yamashita A , Oshima K , Furuya K , Yoshino C , Shiba T , Hattori M , Ogasawara N , Hayashi H , Hiramatsu K
Ref : Lancet , 357 :1225 , 2001
Abstract :
PubMedSearch : Kuroda_2001_Lancet_357_1225
PubMedID: 11418146
Gene_locus related to this paper: staau-LIP , staau-lipas , staau-MW0741 , staau-MW2456 , staau-q6gfm6 , staau-SA0011 , staau-SA0569 , staau-SA0572 , staau-SA0897 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0321 , staau-SAV0446 , staau-SAV0457 , staau-SAV0655 , staau-SAV1014 , staau-SAV1765 , staau-SAV1793 , staau-SAV2188 , staau-SAV2350 , staau-SAV2484 , staau-SAV2594

Title : Staphylococcal lipases: biochemical and molecular characterization - Rosenstein_2000_Biochimie_82_1005
Author(s) : Rosenstein R , Gotz F
Ref : Biochimie , 82 :1005 , 2000
Abstract :
PubMedSearch : Rosenstein_2000_Biochimie_82_1005
PubMedID: 11099797
Gene_locus related to this paper: staau-LIP , staau-lipas , staep-lipas , staep-SE0245 , stahy-lipas , stawa-GEHA , staxy-gehH , staxy-q2tpv1

Title : The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation - Cramton_1999_Infect.Immun_67_5427
Author(s) : Cramton SE , Gerke C , Schnell NF , Nichols WW , Gotz F
Ref : Infect Immun , 67 :5427 , 1999
Abstract :
PubMedSearch : Cramton_1999_Infect.Immun_67_5427
PubMedID: 10496925
Gene_locus related to this paper: staau-LIP

Title : Staphylococcal lipases: molecular characterisation, secretion, and processing - Gotz_1998_Chem.Phys.Lipids_93_15
Author(s) : Gotz F , Verheij HM , Rosenstein R
Ref : Chemistry & Physic of Lipids , 93 :15 , 1998
Abstract :
PubMedSearch : Gotz_1998_Chem.Phys.Lipids_93_15
PubMedID: 9720246
Gene_locus related to this paper: staau-LIP , staau-lipas , staep-lipas , staep-SE0245 , stahy-lipas , stawa-GEHA , staxy-gehH

Title : Comparative biochemical and molecular analysis of the Staphylococcus hyicus, Staphylococcus aureus and a hybrid lipase. Indication for a C-terminal phospholipase domain - Nikoleit_1995_Eur.J.Biochem_228_732
Author(s) : Nikoleit K , Rosenstein R , Verheij HM , Gotz F
Ref : European Journal of Biochemistry , 228 :732 , 1995
Abstract :
PubMedSearch : Nikoleit_1995_Eur.J.Biochem_228_732
PubMedID: 7737171
Gene_locus related to this paper: staau-LIP , stahy-lipas