| Title : Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists - Wang_2002_J.Med.Chem_45_5415 |
| Author(s) : Wang Y , Chackalamannil S , Hu Z , Greenlee WJ , Clader J , Boyle CD , Kaminski JJ , Billard W , Binch H, 3rd , Crosby G , Ruperto V , Duffy RA , Cohen-Williams M , Coffin VL , Cox KA , Grotz DE , Lachowicz JE |
| Ref : Journal of Medicinal Chemistry , 45 :5415 , 2002 |
| Abstract : |
| PubMedSearch : Wang_2002_J.Med.Chem_45_5415 |
| PubMedID: 12459007 |
| Title : Muscarinic agonists and antagonists in the treatment of Alzheimer's disease - Greenlee_2001_Farmaco_56_247 |
| Author(s) : Greenlee W , Clader J , Asberom T , McCombie S , Ford J , Guzik H , Kozlowski J , Li S , Liu C , Lowe D , Vice S , Zhao H , Zhou G , Billard W , Binch H , Crosby R , Duffy R , Lachowicz J , Coffin V , Watkins R , Ruperto V , Strader C , Taylor L , Cox K |
| Ref : Farmaco , 56 :247 , 2001 |
| Abstract : |
| PubMedSearch : Greenlee_2001_Farmaco_56_247 |
| PubMedID: 11421251 |
| Title : Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788 - Lachowicz_2001_Life.Sci_68(22-23)_2585 |
| Author(s) : Lachowicz JE , Duffy RA , Ruperto V , Kozlowski J , Zhou G , Clader J , Billard W , Binch H, 3rd , Crosby G , Cohen-Williams M , Strader CD , Coffin V |
| Ref : Life Sciences , 68 :2585 , 2001 |
| Abstract : |
| PubMedSearch : Lachowicz_2001_Life.Sci_68(22-23)_2585 |
| PubMedID: 11392630 |
| Title : SCH 57790: a novel M2 receptor selective antagonist - Lachowicz_1999_Life.Sci_64(6-7)_535 |
| Author(s) : Lachowicz JE , Lowe D , Duffy RA , Ruperto V , Taylor LA , Guzik H , Brown J , Berger JG , Tice M , McQuade R , Kozlowski J , Clader J , Strader CD , Murgolo N |
| Ref : Life Sciences , 64 :535 , 1999 |
| Abstract : |
| PubMedSearch : Lachowicz_1999_Life.Sci_64(6-7)_535 |
| PubMedID: 10069520 |