| Title : Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists - Wang_2002_J.Med.Chem_45_5415 |
| Author(s) : Wang Y , Chackalamannil S , Hu Z , Greenlee WJ , Clader J , Boyle CD , Kaminski JJ , Billard W , Binch H, 3rd , Crosby G , Ruperto V , Duffy RA , Cohen-Williams M , Coffin VL , Cox KA , Grotz DE , Lachowicz JE |
| Ref : Journal of Medicinal Chemistry , 45 :5415 , 2002 |
| Abstract : Wang_2002_J.Med.Chem_45_5415 |
| ESTHER : Wang_2002_J.Med.Chem_45_5415 |
| PubMedSearch : Wang_2002_J.Med.Chem_45_5415 |
| PubMedID: 12459007 |
| Title : Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution - Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| Author(s) : Boyle CD , Chackalamannil S , Clader JW , Greenlee WJ , Josien HB , Kaminski JJ , Kozlowski JA , McCombie SW , Nazareno DV , Tagat JR , Wang Y , Zhou G , Billard W , Binch H , Crosby G , Cohen-Williams M , Coffin VL , Cox KA , Grotz DE , Duffy RA , Ruperto V , Lachowicz JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 11 :2311 , 2001 |
| Abstract : Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| ESTHER : Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| PubMedSearch : Boyle_2001_Bioorg.Med.Chem.Lett_11_2311 |
| PubMedID: 11527721 |