Cohen O

General

Full name : Cohen Ofer

First name : Ofer

Mail : Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, 24 Rueven St., P.O. Box 19, Ness-Ziona 74100

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Country : Israel

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References (18)

Title : Acetylcholinesterase-Fc Fusion Protein (AChE-Fc): A Novel Potential Organophosphate Bioscavenger with Extended Plasma Half-Life - Noy-Porat_2015_Bioconjug.Chem_26_1753
Author(s) : Noy-Porat T , Cohen O , Ehrlich S , Epstein E , Alcalay R , Mazor O
Ref : Bioconjug Chem , 26 :1753 , 2015
Abstract :
PubMedSearch : Noy-Porat_2015_Bioconjug.Chem_26_1753
PubMedID: 26121420

Title : Next generation OP-bioscavengers: a circulatory long-lived 4-PEG hypolysine mutant of F338A-HuAChE with optimal pharmacokinetics and pseudo-catalytic characteristics - Kronman_2010_Chem.Biol.Interact_187_253
Author(s) : Kronman C , Cohen O , Mazor O , Ordentlich A , Raveh L , Velan B , Shafferman A
Ref : Chemico-Biological Interactions , 187 :253 , 2010
Abstract :
PubMedSearch : Kronman_2010_Chem.Biol.Interact_187_253
PubMedID: 20005217

Title : Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase - Mazor_2008_Mol.Pharmacol_74_755
Author(s) : Mazor O , Cohen O , Kronman C , Raveh L , Stein D , Ordentlich A , Shafferman A
Ref : Molecular Pharmacology , 74 :755 , 2008
Abstract :
PubMedSearch : Mazor_2008_Mol.Pharmacol_74_755
PubMedID: 18523134

Title : Polyethylene-glycol conjugated recombinant human acetylcholinesterase serves as an efficacious bioscavenger against soman intoxication - Kronman_2007_Toxicology_233_40
Author(s) : Kronman C , Cohen O , Raveh L , Mazor O , Ordentlich A , Shafferman A
Ref : Toxicology , 233 :40 , 2007
Abstract :
PubMedSearch : Kronman_2007_Toxicology_233_40
PubMedID: 17045722

Title : Controlled concealment of exposed clearance and immunogenic domains by site-specific polyethylene glycol attachment to acetylcholinesterase hypolysine mutants - Cohen_2007_J.Biol.Chem_282_35491
Author(s) : Cohen O , Kronman C , Lazar A , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 282 :35491 , 2007
Abstract :
PubMedSearch : Cohen_2007_J.Biol.Chem_282_35491
PubMedID: 17932038

Title : Comparison of polyethylene glycol-conjugated recombinant human acetylcholinesterase and serum human butyrylcholinesterase as bioscavengers of organophosphate compounds - Cohen_2006_Mol.Pharmacol_70_1121
Author(s) : Cohen O , Kronman C , Raveh L , Mazor O , Ordentlich A , Shafferman A
Ref : Molecular Pharmacology , 70 :1121 , 2006
Abstract :
PubMedSearch : Cohen_2006_Mol.Pharmacol_70_1121
PubMedID: 16801396

Title : Host-regulated disposition of mammalian AChEs - Kronman_2005_Chem.Biol.Interact_157-158_51
Author(s) : Kronman C , Cohen O , Velan B , Shafferman A
Ref : Chemico-Biological Interactions , 157-158 :51 , 2005
Abstract :
PubMedSearch : Kronman_2005_Chem.Biol.Interact_157-158_51
PubMedID: 16289063

Title : Generation of pharmacokinetically improved recombinant human acetylcholinesterase by polyethylene glycol modification. -
Author(s) : Cohen O , Kronman C , Chitlaru T , Ordentlich A , Velan B , Shafferman A
Ref : Cholinergic Mechanisms, CRC Press :519 , 2004
PubMedID:

Title : Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta) - Cohen_2004_Biochem.J_378_117
Author(s) : Cohen O , Kronman C , Velan B , Shafferman A
Ref : Biochemical Journal , 378 :117 , 2004
Abstract :
PubMedSearch : Cohen_2004_Biochem.J_378_117
PubMedID: 14575524
Gene_locus related to this paper: macmu-ACHE

Title : The molecular neurobiology of acetylcholinesterase variants. -
Author(s) : Meshorer E , Cohen O , Yirmya R , Ginzberg D , Glick D
Ref : Cholinergic Mechanisms, CRC Press :119 , 2004
PubMedID:

Title : Poster (35) The hierarchy of post-translation modifications determining circulatory longevity of acetylcholinesterase. -
Author(s) : Velan B , Kronman C , Chitlaru T , Cohen O , Ordentlich A , Shafferman A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :339 , 2004
PubMedID:

Title : Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma readthrough acetylcholinesterase - Cohen_2003_J.Mol.Neurosci_21_199
Author(s) : Cohen O , Reichenberg A , Perry C , Ginzberg D , Pollmacher T , Soreq H , Yirmiya R
Ref : Journal of Molecular Neuroscience , 21 :199 , 2003
Abstract :
PubMedSearch : Cohen_2003_J.Mol.Neurosci_21_199
PubMedID: 14645987

Title : Upregulation of neuronal nicotinic receptor subunits alpha4, beta2, and alpha7 in transgenic mice overexpressing human acetylcholinesterase - Svedberg_2002_J.Mol.Neurosci_18_211
Author(s) : Svedberg MM , Svensson AL , Johnson M , Lee M , Cohen O , Court J , Soreq H , Perry E , Nordberg A
Ref : Journal of Molecular Neuroscience , 18 :211 , 2002
Abstract :
PubMedSearch : Svedberg_2002_J.Mol.Neurosci_18_211
PubMedID: 12059039

Title : Neuronal overexpression of 'readthrough' acetylcholinesterase is associated with antisense-suppressible behavioral impairments - Cohen_2002_Mol.Psychiatry_7_874
Author(s) : Cohen O , Erb C , Ginzberg D , Pollak Y , Seidman S , Shoham S , Yirmiya R , Soreq H
Ref : Mol Psychiatry , 7 :874 , 2002
Abstract :
PubMedSearch : Cohen_2002_Mol.Psychiatry_7_874
PubMedID: 12232781

Title : Effect of chemical modification of recombinant human acetylcholinesterase by polyethylene glycol on its circulatory longevity - Cohen_2001_Biochem.J_357_795
Author(s) : Cohen O , Kronman C , Chitlaru T , Ordentlich A , Velan B , Shafferman A
Ref : Biochemical Journal , 357 :795 , 2001
Abstract :
PubMedSearch : Cohen_2001_Biochem.J_357_795
PubMedID: 11463350

Title : Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases - Perry_2000_Eur.J.Pharmacol_393_215
Author(s) : Perry E , Martin-Ruiz C , Lee M , Griffiths M , Johnson M , Piggott M , Haroutunian V , Buxbaum JD , Nasland J , Davis K , Gotti C , Clementi F , Tzartos SJ , Cohen O , Soreq H , Jaros E , Perry R , Ballard C , McKeith I , Court J
Ref : European Journal of Pharmacology , 393 :215 , 2000
Abstract :
PubMedSearch : Perry_2000_Eur.J.Pharmacol_393_215
PubMedID: 10771016

Title : Antisense prevention of neuronal damages following head injury in mice - Shohami_2000_J.Mol.Med.(Berl)_78_228
Author(s) : Shohami E , Kaufer D , Chen Y , Seidman S , Cohen O , Ginzberg D , Melamed-Book N , Yirmiya R , Soreq H
Ref : J Mol Med (Berl) , 78 :228 , 2000
Abstract :
PubMedSearch : Shohami_2000_J.Mol.Med.(Berl)_78_228
PubMedID: 10933585

Title : Multilevel Approaches to AChE-Induced Impairments in Learning and Memory -
Author(s) : Seidman S , Cohen O , Ginzberg D , Eichengreen E , Pollak Y , Yirmiya R , Soreq H
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :183 , 1998
PubMedID: