Lazar A

General

Full name : Lazar Arye

First name : Arye

Mail : Dept. of Biotechnology, Israel Inst. for BioI. Res., P.O.B. 19, 70450 Ness-Ziona

Zip Code :

City :

Country : Israel

Email :

Phone : (972) 8 381567

Fax : (972) 8 401094

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References (15)

Title : Controlled concealment of exposed clearance and immunogenic domains by site-specific polyethylene glycol attachment to acetylcholinesterase hypolysine mutants - Cohen_2007_J.Biol.Chem_282_35491
Author(s) : Cohen O , Kronman C , Lazar A , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 282 :35491 , 2007
PubMedID: 17932038

Title : The role of AChE active site gorge in determining stereoselectivity of charged and noncharged VX enantiomers - Ordentlich_2005_Chem.Biol.Interact_157-158_191
Author(s) : Ordentlich A , Barak D , Sod-Moriah G , Kaplan D , Mizrahi D , Segall Y , Kronman C , Karton Y , Lazar A , Marcus D , Velan B , Shafferman A
Ref : Chemico-Biological Interactions , 157-158 :191 , 2005
PubMedID: 16289014

Title : Some basic rules governing oligosaccharide-dependent circulatory residence of glycoproteins are revealed by MALDI-TOF mapping of the multiple N-glycans associated with recombinant bovine acetylcholinesterase. -
Author(s) : Kronman C , Chitlaru T , Seliger N , Lazar S , Lazar A , Zilberstein L , Velan B , Shafferman A
Ref : Cholinergic Mechanisms, CRC Press :613 , 2004
PubMedID:

Title : Stereoselectivity toward VX is determined by interactions with residues of the acyl pocket as well as of the peripheral anionic site of AChE - Ordentlich_2004_Biochemistry_43_11255
Author(s) : Ordentlich A , Barak D , Sod-Moriah G , Kaplan D , Mizrahi D , Segall Y , Kronman C , Karton Y , Lazar A , Marcus D , Velan B , Shafferman A
Ref : Biochemistry , 43 :11255 , 2004
PubMedID: 15366935

Title : Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II - Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385
Author(s) : Kryger G , Harel M , Giles K , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL
Ref : Acta Crystallographica D Biol Crystallogr , 56 :1385 , 2000
PubMedID: 11053835
Gene_locus related to this paper: human-ACHE

Title : 3D Structure at 2.7 Resolution of Native and E202Q Mutant Human Acetylcholinesterase Complexed with Fasciculin-II -
Author(s) : Kryger G , Giles K , Harel M , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :323 , 1998
PubMedID:

Title : 3D Structure of a Complex of Human Acetylcholinesterase with Fasciculin-II at 2.7 Resolution -
Author(s) : Kryger G , Giles K , Harel M , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :370 , 1998
PubMedID:

Title : Molecular Aspects of Catalysis and of Allosteric Regulation of Aceytlcholinesterases -
Author(s) : Shafferman A , Ordentlich A , Barak D , Kronman C , Ariel N , Leitner M , Segall Y , Bromberg A , Reuveny S , Marcus D , Bino T , Lazar A , Cohen S , Velan B
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :189 , 1995
PubMedID:

Title : Allosteric modulation of acetylcholinesterase activity by peripheral ligands involves a conformational transition of the anionic subsite - Barak_1995_Biochemistry_34_15444
Author(s) : Barak D , Ordentlich A , Bromberg A , Kronman C , Marcus D , Lazar A , Ariel N , Velan B , Shafferman A
Ref : Biochemistry , 34 :15444 , 1995
PubMedID: 7492545

Title : Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core - Barak_1994_J.Biol.Chem_269_6296
Author(s) : Barak D , Kronman C , Ordentlich A , Ariel N , Bromberg A , Marcus D , Lazar A , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 269 :6296 , 1994
PubMedID: 8119978

Title : Evaluation of anchorage-dependent cell propagation systems for production of human acetylcholinesterase by recombinant 293 cells - Lazar_1993_Cytotech_13_115
Author(s) : Lazar A , Reuveny S , Kronman C , Velan B , Shafferman A
Ref : Cytotechnology , 13 :115 , 1993
PubMedID: 7764576

Title : Production and secretion of high levels of recombinant human acetylcholinesterase in cultured cell lines: microheterogeneity of the catalytic subunit - Kronman_1992_Gene_121_295
Author(s) : Kronman C , Velan B , Gozes Y , Leitner M , Flashner Y , Lazar A , Marcus D , Sery T , Papier Y , Grosfeld H , Cohen S , Shafferman A
Ref : Gene , 121 :295 , 1992
PubMedID: 1446827

Title : The effect of elimination of intersubunit disulfide bonds on the activity, assembly, and secretion of recombinant human acetylcholinesterase. Expression of acetylcholinesterase Cys-580----Ala mutant - Velan_1991_J.Biol.Chem_266_23977
Author(s) : Velan B , Grosfeld H , Kronman C , Leitner M , Gozes Y , Lazar A , Flashner Y , Marcus D , Cohen S , Shafferman A
Ref : Journal of Biological Chemistry , 266 :23977 , 1991
PubMedID: 1748670

Title : Equipment and procedures for production of monoclonal antibodies in culture -
Author(s) : Reuveny S , Lazar A
Ref : Adv Biotechnol Processes , 11 :45 , 1989
PubMedID: 2644947

Title : An immobilized hybridoma culture perfusion system for production of monoclonal antibodies - Lazar_1988_Cytotech_1_331
Author(s) : Lazar A , Silberstein L , Mizrahi A , Reuveny S
Ref : Cytotechnology , 1 :331 , 1988
PubMedID: 22359168