Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
Author(s) :
Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
Ref :
Journal of Medicinal Chemistry , : , 2021 |
Abstract : Ikeda_2021_J.Med.Chem__ |
ESTHER : Ikeda_2021_J.Med.Chem__ |
PubMedSearch : Ikeda_2021_J.Med.Chem__ |
PubMedID: 34328319 |
Gene_locus related to this paper:
human-MGLL |