| Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
| Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Ikeda_2021_J.Med.Chem__ |
| PubMedID: 34328319 |
| Gene_locus related to this paper: human-MGLL |
| Title : Chimeric mice with humanized liver as a model for testing organophosphate and carbamate pesticide exposure - Suemizu_2018_Pest.Manag.Sci_74_1424 |
| Author(s) : Suemizu H , Kawai K , Murayama N , Nakamura M , Yamazaki H |
| Ref : Pest Manag Sci , 74 :1424 , 2018 |
| Abstract : |
| PubMedSearch : Suemizu_2018_Pest.Manag.Sci_74_1424 |
| PubMedID: 29235720 |
| Title : MALT Lymphoma, Stress Ulcer and Cholinergic Nerves from the Viewpoint of Bilateral and Unilateral Truncal Vagotomy and Substance P - Kodama_2018_Curr.Pharm.Des_24_1961 |
| Author(s) : Kodama Y , Sasaki K , Murasato F , Overby A , Takahashi S , Murayama SY , Matsui H , Nakamura M |
| Ref : Curr Pharm Des , 24 :1961 , 2018 |
| Abstract : |
| PubMedSearch : Kodama_2018_Curr.Pharm.Des_24_1961 |
| PubMedID: 29766790 |
| Title : Early use of donepezil against psychosis and cognitive decline in Parkinson's disease: a randomised controlled trial for 2 years - Sawada_2018_J.Neurol.Neurosurg.Psychiatry_89_1332 |
| Author(s) : Sawada H , Oeda T , Kohsaka M , Umemura A , Tomita S , Park K , Mizoguchi K , Matsuo H , Hasegawa K , Fujimura H , Sugiyama H , Nakamura M , Kikuchi S , Yamamoto K , Fukuda T , Ito S , Goto M , Kiyohara K , Kawamura T |
| Ref : Journal of Neurology Neurosurg Psychiatry , 89 :1332 , 2018 |
| Abstract : |
| PubMedSearch : Sawada_2018_J.Neurol.Neurosurg.Psychiatry_89_1332 |
| PubMedID: 30076270 |
| Title : Significance of Cholinergic and Peptidergic Nerves in Stress-Induced Ulcer and MALT Lymphoma Formation - Nakamura_2017_Curr.Pharm.Des_23_3993 |
| Author(s) : Nakamura M , Overby A , Uehara A , Oda M , Takahashi S , Murayama SY , Matsui H |
| Ref : Curr Pharm Des , 23 :3993 , 2017 |
| Abstract : |
| PubMedSearch : Nakamura_2017_Curr.Pharm.Des_23_3993 |
| PubMedID: 28190393 |
| Title : Clinical outcome of lower esophageal sphincter- and vagus-nerve-preserving partial cardiectomy for early gastric cancer of the subcardia - Matsumoto_2015_Gastric.Cancer_18_669 |
| Author(s) : Matsumoto H , Murakami H , Kubota H , Higashida M , Nakamura M , Hirai T |
| Ref : Gastric Cancer , 18 :669 , 2015 |
| Abstract : |
| PubMedSearch : Matsumoto_2015_Gastric.Cancer_18_669 |
| PubMedID: 24906556 |
| Title : Decreased expression of acetylcholine esterase in cholinergic urticaria with hypohidrosis or anhidrosis - |
| Author(s) : Sawada Y , Nakamura M , Bito T , Sakabe JI , Kabashima-Kubo R , Hino R , Kobayashi M , Tokura Y |
| Ref : Journal of Investigative Dermatology , 134 :276 , 2014 |
| PubMedID: 23748235 |
| Title : A homozygous mutation, c.736T>A (p.C246S), in LIPH gene in a patient manifesting woolly hair, hypotrichosis, hearing difficulty, cleft palate and amblyopia - |
| Author(s) : Hamada K , Kubo R , Nishio D , Nakamura M |
| Ref : Eur J Dermatol , 24 :272 , 2014 |
| PubMedID: 24722066 |
| Gene_locus related to this paper: human-LIPH |
| Title : A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1alpha in autosomal recessive wooly hair\/hypotrichosis - |
| Author(s) : Yoshizawa M , Nakamura M , Farooq M , Inoue A , Aoki J , Shimomura Y |
| Ref : J Dermatol Sci , 72 :61 , 2013 |
| PubMedID: 23768866 |
| Gene_locus related to this paper: human-LIPH |
| Title : Effects of a peripheral cholinesterase inhibitor on cytokine production and autonomic nervous activity in a rat model of sepsis - Setoguchi_2012_Cytokine_57_238 |
| Author(s) : Setoguchi D , Yatsuki H , Sadahiro T , Nakamura M , Hirayama Y , Watanabe E , Tateishi Y , Oda S |
| Ref : Cytokine , 57 :238 , 2012 |
| Abstract : |
| PubMedSearch : Setoguchi_2012_Cytokine_57_238 |
| PubMedID: 22138106 |
| Title : Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-y lcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Yoshida_2012_Bioorg.Med.Chem_20_5705 |
| Author(s) : Yoshida T , Akahoshi F , Sakashita H , Kitajima H , Nakamura M , Sonda S , Takeuchi M , Tanaka Y , Ueda N , Sekiguchi S , Ishige T , Shima K , Nabeno M , Abe Y , Anabuki J , Soejima A , Yoshida K , Takashina Y , Ishii S , Kiuchi S , Fukuda S , Tsutsumiuchi R , Kosaka K , Murozono T , Nakamaru Y , Utsumi H , Masutomi N , Kishida H , Miyaguchi I , Hayashi Y |
| Ref : Bioorganic & Medicinal Chemistry , 20 :5705 , 2012 |
| Abstract : |
| PubMedSearch : Yoshida_2012_Bioorg.Med.Chem_20_5705 |
| PubMedID: 22959556 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair - Yoshimasu_2011_J.Dermatol_38_900 |
| Author(s) : Yoshimasu T , Kanazawa N , Kambe N , Nakamura M , Furukawa F |
| Ref : J Dermatol , 38 :900 , 2011 |
| Abstract : |
| PubMedSearch : Yoshimasu_2011_J.Dermatol_38_900 |
| PubMedID: 21352330 |
| Gene_locus related to this paper: human-LIPH |
| Title : Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population - Hotta_2010_J.Hum.Genet_55_738 |
| Author(s) : Hotta K , Nakamura M , Nakamura T , Matsuo T , Nakata Y , Kamohara S , Miyatake N , Kotani K , Komatsu R , Itoh N , Mineo I , Wada J , Yoneda M , Nakajima A , Funahashi T , Miyazaki S , Tokunaga K , Kawamoto M , Masuzaki H , Ueno T , Hamaguchi K , Tanaka K , Yamada K , Hanafusa T , Oikawa S , Yoshimatsu H , Nakao K , Sakata T , Matsuzawa Y , Nakamura Y , Kamatani N |
| Ref : J Hum Genet , 55 :738 , 2010 |
| Abstract : |
| PubMedSearch : Hotta_2010_J.Hum.Genet_55_738 |
| PubMedID: 20703240 |
| Title : Differential display analysis of gene expression in female-to-male sex-reversing gonads of the frog Rana rugosa - Okada_2008_Gen.Comp.Endocrinol_155_623 |
| Author(s) : Okada G , Maruo K , Funada S , Nakamura M |
| Ref : General & Comparative Endocrinology , 155 :623 , 2008 |
| Abstract : |
| PubMedSearch : Okada_2008_Gen.Comp.Endocrinol_155_623 |
| PubMedID: 17942098 |
| Gene_locus related to this paper: rugru-a8cep5 |
| Title : Phylogenetic diversity and cosymbiosis in the bioluminescent symbioses of Photobacterium mandapamensis - Kaeding_2007_Appl.Environ.Microbiol_73_3173 |
| Author(s) : Kaeding AJ , Ast JC , Pearce MM , Urbanczyk H , Kimura S , Endo H , Nakamura M , Dunlap PV |
| Ref : Applied Environmental Microbiology , 73 :3173 , 2007 |
| Abstract : |
| PubMedSearch : Kaeding_2007_Appl.Environ.Microbiol_73_3173 |
| PubMedID: 17369329 |
| Gene_locus related to this paper: phole-lxd2 , phopo-luxd |
| Title : Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection - Migita_2006_Hum.Immunol_67_27 |
| Author(s) : Migita K , Abiru S , Maeda Y , Daikoku M , Ohata K , Nakamura M , Komori A , Yano K , Yatsuhashi H , Eguchi K , Ishibashi H |
| Ref : Hum Immunol , 67 :27 , 2006 |
| Abstract : |
| PubMedSearch : Migita_2006_Hum.Immunol_67_27 |
| PubMedID: 16698422 |
| Title : Antisense transcription in the mammalian transcriptome - Katayama_2005_Science_309_1564 |
| Author(s) : Katayama S , Tomaru Y , Kasukawa T , Waki K , Nakanishi M , Nakamura M , Nishida H , Yap CC , Suzuki M , Kawai J , Suzuki H , Carninci P , Hayashizaki Y , Wells C , Frith M , Ravasi T , Pang KC , Hallinan J , Mattick J , Hume DA , Lipovich L , Batalov S , Engstrom PG , Mizuno Y , Faghihi MA , Sandelin A , Chalk AM , Mottagui-Tabar S , Liang Z , Lenhard B , Wahlestedt C |
| Ref : Science , 309 :1564 , 2005 |
| Abstract : |
| PubMedSearch : Katayama_2005_Science_309_1564 |
| PubMedID: 16141073 |
| Gene_locus related to this paper: mouse-lipli , mouse-Ppgb , mouse-q3uuq7 |
| Title : 1-((S)-gamma-substituted prolyl)-(S)-2-cyanopyrrolidine as a novel series of highly potent DPP-IV inhibitors - Sakashita_2005_Bioorg.Med.Chem.Lett_15_2441 |
| Author(s) : Sakashita H , Kitajima H , Nakamura M , Akahoshi F , Hayashi Y |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :2441 , 2005 |
| Abstract : |
| PubMedSearch : Sakashita_2005_Bioorg.Med.Chem.Lett_15_2441 |
| PubMedID: 15863294 |
| Title : Molecular cloning, nucleotide sequence and characteristics of a xylanase gene (xynA) from Ruminococcus albus 7. - |
| Author(s) : Nakamura M , Nagamine T , Takenaka A , Aminov RI , Ogata K , Tajima K , Matsui H , Benno Y , Itabashi H |
| Ref : Anim Sci J , 73 :347 , 2002 |
| PubMedID: |
| Gene_locus related to this paper: rumal-XYNB |
| Title : DNA sequence and comparison of virulence plasmids from Rhodococcus equi ATCC 33701 and 103 - Takai_2000_Infect.Immun_68_6840 |
| Author(s) : Takai S , Hines SA , Sekizaki T , Nicholson VM , Alperin DA , Osaki M , Takamatsu D , Nakamura M , Suzuki K , Ogino N , Kakuda T , Dan H , Prescott JF |
| Ref : Infect Immun , 68 :6840 , 2000 |
| Abstract : |
| PubMedSearch : Takai_2000_Infect.Immun_68_6840 |
| PubMedID: 11083803 |
| Gene_locus related to this paper: coreq-d9i5p0 |
| Title : Migration of organophosphorus insecticides cyanophos and prothiofos residues from impregnated paper bags to Japanese apple-pears (Pyrus pyrifolia nakai cv. Nijisseiki) - Katami_2000_J.Agric.Food.Chem_48_2499 |
| Author(s) : Katami T , Nakamura M , Yasuhara A , Shibamoto T |
| Ref : Journal of Agricultural and Food Chemistry , 48 :2499 , 2000 |
| Abstract : |
| PubMedSearch : Katami_2000_J.Agric.Food.Chem_48_2499 |
| PubMedID: 10888575 |
| Title : Innervation of testes in the tilapia Oreochromis niloticus - |
| Author(s) : Nakamura M , Nagahama Y |
| Ref : Aquaculture , 135 :41 , 1995 |
| PubMedID: |
| Title : Characterization of esterases involved in the hydrolysis of dipivefrin hydrochloride - Nakamura_1993_Ophthalmic.Res_25_46 |
| Author(s) : Nakamura M , Shirasawa E , Hikida M |
| Ref : Ophthalmic Res , 25 :46 , 1993 |
| Abstract : |
| PubMedSearch : Nakamura_1993_Ophthalmic.Res_25_46 |
| PubMedID: 8446367 |
| Title : No changes in rabbit corneal esterase activities with dipivefrine hydrochloride instillation for 4 weeks - |
| Author(s) : Nakamura M , Shirasawa E , Hikida M |
| Ref : Graefes Arch Clin Exp Ophthalmol , 231 :551 , 1993 |
| PubMedID: 8224961 |