Sasaki M

Title : The mechanism of Atg15-mediated membrane disruption in autophagy - Kagohashi_2023_J.Cell.Biol_222_e202306120

Author(s) : Kagohashi Y , Sasaki M , May AI , Kawamata T , Ohsumi Y

Ref : Journal of Cell Biology , 222 : , 2023

Abstract :

PubMedSearch : Kagohashi_2023_J.Cell.Biol_222_e202306120

Gene_locus related to this paper: yeast-ATG15

Title : Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models - Sasaki_2021_Arterioscler.Thromb.Vasc.Biol_41_360

Author(s) : Sasaki M , Delawary M , Sakurai H , Kobayashi H , Nakao N , Tsuru H , Fukushima Y , Honzumi S , Moriyama S , Wada N , Kaneko T , Yamada K , Terasaka N , Kubota K

Ref : Arterioscler Thromb Vasc Biol , 41 :360 , 2021

Abstract :

PubMedSearch : Sasaki_2021_Arterioscler.Thromb.Vasc.Biol_41_360

PubMedID: 33086872

Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__

Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M

Ref : Journal of Medicinal Chemistry , : , 2021

Abstract :

PubMedSearch : Ikeda_2021_J.Med.Chem__

PubMedID: 34328319

Gene_locus related to this paper: human-MGLL

Title : Dipeptidyl Peptidase 9 Increases Chemoresistance and is an Indicator of Poor Prognosis in Colorectal Cancer - Saso_2020_Ann.Surg.Oncol_27_4337

Author(s) : Saso K , Miyoshi N , Fujino S , Sasaki M , Yasui M , Ohue M , Ogino T , Takahashi H , Uemura M , Matsuda C , Mizushima T , Doki Y , Eguchi H

Ref : Annals of Surgery Oncol , 27 :4337 , 2020

Abstract :

PubMedSearch : Saso_2020_Ann.Surg.Oncol_27_4337

PubMedID: 32734369

Title : Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase - Hattori_2019_J.Med.Chem_62_2362

Author(s) : Hattori Y , Aoyama K , Maeda J , Arimura N , Takahashi Y , Sasaki M , Fujinaga M , Seki C , Nagai Y , Kawamura K , Yamasaki T , Zhang MR , Higuchi M , Koike T

Ref : Journal of Medicinal Chemistry , 62 :2362 , 2019

Abstract :

PubMedSearch : Hattori_2019_J.Med.Chem_62_2362

PubMedID: 30753069

Gene_locus related to this paper: human-MGLL

Title : Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors - Aida_2018_J.Med.Chem_61_9205

Author(s) : Aida J , Fushimi M , Kusumoto T , Sugiyama H , Arimura N , Ikeda S , Sasaki M , Sogabe S , Aoyama K , Koike T

Ref : Journal of Medicinal Chemistry , 61 :9205 , 2018

Abstract :

PubMedSearch : Aida_2018_J.Med.Chem_61_9205

PubMedID: 30251836

Gene_locus related to this paper: human-MGLL

Title : Decreased resting energy expenditure in patients with Duchenne muscular dystrophy - Shimizu-Fujiwara_2012_Brain.Dev_34_206

Author(s) : Shimizu-Fujiwara M , Komaki H , Nakagawa E , Mori-Yoshimura M , Oya Y , Fujisaki T , Tokita Y , Kubota N , Shimazaki R , Sato K , Ishikawa T , Goto K , Mochizuki H , Takanoha S , Ogata K , Kawai M , Konagaya M , Miyazaki T , Tatara K , Sugai K , Sasaki M

Ref : Brain Dev , 34 :206 , 2012

Abstract :

PubMedSearch : Shimizu-Fujiwara_2012_Brain.Dev_34_206

PubMedID: 21632191

Title : Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 - Banno_2011_Bioorg.Med.Chem_19_4953

Author(s) : Banno Y , Miyamoto Y , Sasaki M , Oi S , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Tawada M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H

Ref : Bioorganic & Medicinal Chemistry , 19 :4953 , 2011

Abstract :

PubMedSearch : Banno_2011_Bioorg.Med.Chem_19_4953

PubMedID: 21764322

Gene_locus related to this paper: human-DPP4

Title : Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554 - Maezaki_2011_Bioorg.Med.Chem_19_4482

Author(s) : Maezaki H , Banno Y , Miyamoto Y , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Sasaki M , Tsubotani S , Tani A , Funami M , Yamamoto Y , Tawada M , Aertgeerts K , Yano J , Oi S

Ref : Bioorganic & Medicinal Chemistry , 19 :4482 , 2011

Abstract :

PubMedSearch : Maezaki_2011_Bioorg.Med.Chem_19_4482

PubMedID: 21741847

Gene_locus related to this paper: human-DPP4

Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831

Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H

Ref : Journal of Medicinal Chemistry , 54 :831 , 2011

Abstract :

PubMedSearch : Miyamoto_2011_J.Med.Chem_54_831

PubMedID: 21218817

Gene_locus related to this paper: human-DPP4

Title : Acetylcholinesterase activity, choline acetyltransferase and vesicular acetylcholine transporter immunoreactivities in the rat adrenal gland during postnatal development - Murabayashi_2009_Anat.Rec.(Hoboken)_292_371

Author(s) : Murabayashi H , Kuramoto H , Ishikawa K , Iwamoto J , Miyakawa K , Tanaka K , Sekikawa M , Sasaki M , Kitamura N , Oomori Y

Ref : Anatomical Record (Hoboken) , 292 :371 , 2009

Abstract :

PubMedSearch : Murabayashi_2009_Anat.Rec.(Hoboken)_292_371

PubMedID: 19248156

Title : Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic gamma-secretase inhibitors - Fuwa_2007_ACS.Chem.Biol_2_408

Author(s) : Fuwa H , Takahashi Y , Konno Y , Watanabe N , Miyashita H , Sasaki M , Natsugari H , Kan T , Fukuyama T , Tomita T , Iwatsubo T

Ref : ACS Chemical Biology , 2 :408 , 2007

Abstract :

PubMedSearch : Fuwa_2007_ACS.Chem.Biol_2_408

PubMedID: 17530731

Title : Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3 ,2,1-ij]quinolin-4-one (TAK-802) and related compounds - Ishichi_2005_Bioorg.Med.Chem_13_1901

Author(s) : Ishichi Y , Sasaki M , Setoh M , Tsukamoto T , Miwatashi S , Nagabukuro H , Okanishi S , Imai S , Saikawa R , Doi T , Ishihara Y

Ref : Bioorganic & Medicinal Chemistry , 13 :1901 , 2005

Abstract :

PubMedSearch : Ishichi_2005_Bioorg.Med.Chem_13_1901

PubMedID: 15727846

Title : Complete sequencing and characterization of 21,243 full-length human cDNAs - Ota_2004_Nat.Genet_36_40

Author(s) : Ota T , Suzuki Y , Nishikawa T , Otsuki T , Sugiyama T , Irie R , Wakamatsu A , Hayashi K , Sato H , Nagai K , Kimura K , Makita H , Sekine M , Obayashi M , Nishi T , Shibahara T , Tanaka T , Ishii S , Yamamoto J , Saito K , Kawai Y , Isono Y , Nakamura Y , Nagahari K , Murakami K , Yasuda T , Iwayanagi T , Wagatsuma M , Shiratori A , Sudo H , Hosoiri T , Kaku Y , Kodaira H , Kondo H , Sugawara M , Takahashi M , Kanda K , Yokoi T , Furuya T , Kikkawa E , Omura Y , Abe K , Kamihara K , Katsuta N , Sato K , Tanikawa M , Yamazaki M , Ninomiya K , Ishibashi T , Yamashita H , Murakawa K , Fujimori K , Tanai H , Kimata M , Watanabe M , Hiraoka S , Chiba Y , Ishida S , Ono Y , Takiguchi S , Watanabe S , Yosida M , Hotuta T , Kusano J , Kanehori K , Takahashi-Fujii A , Hara H , Tanase TO , Nomura Y , Togiya S , Komai F , Hara R , Takeuchi K , Arita M , Imose N , Musashino K , Yuuki H , Oshima A , Sasaki N , Aotsuka S , Yoshikawa Y , Matsunawa H , Ichihara T , Shiohata N , Sano S , Moriya S , Momiyama H , Satoh N , Takami S , Terashima Y , Suzuki O , Nakagawa S , Senoh A , Mizoguchi H , Goto Y , Shimizu F , Wakebe H , Hishigaki H , Watanabe T , Sugiyama A , Takemoto M , Kawakami B , Watanabe K , Kumagai A , Itakura S , Fukuzumi Y , Fujimori Y , Komiyama M , Tashiro H , Tanigami A , Fujiwara T , Ono T , Yamada K , Fujii Y , Ozaki K , Hirao M , Ohmori Y , Kawabata A , Hikiji T , Kobatake N , Inagaki H , Ikema Y , Okamoto S , Okitani R , Kawakami T , Noguchi S , Itoh T , Shigeta K , Senba T , Matsumura K , Nakajima Y , Mizuno T , Morinaga M , Sasaki M , Togashi T , Oyama M , Hata H , Komatsu T , Mizushima-Sugano J , Satoh T , Shirai Y , Takahashi Y , Nakagawa K , Okumura K , Nagase T , Nomura N , Kikuchi H , Masuho Y , Yamashita R , Nakai K , Yada T , Ohara O , Isogai T , Sugano S

Ref : Nat Genet , 36 :40 , 2004

Abstract :

PubMedSearch : Ota_2004_Nat.Genet_36_40

PubMedID: 14702039

Gene_locus related to this paper: human-ABHD1 , human-ABHD4 , human-ABHD12 , human-ABHD16A , human-ACOT1 , human-LDAH , human-ABHD18 , human-CES1 , human-CES4A , human-CES5A , human-CPVL , human-DAGLB , human-EPHX2 , human-KANSL3 , human-LIPA , human-LPL , human-MEST , human-NDRG1 , human-NLGN1 , human-NLGN4X , human-PRCP , human-PRSS16 , human-SERAC1 , human-TMEM53 , human-cb069

Title : A novel tetrahydrofolate-dependent O-demethylase gene is essential for growth of Sphingomonas paucimobilis SYK-6 with syringate - Masai_2004_J.Bacteriol_186_2757

Author(s) : Masai E , Sasaki M , Minakawa Y , Abe T , Sonoki T , Miyauchi K , Katayama Y , Fukuda M

Ref : Journal of Bacteriology , 186 :2757 , 2004

Abstract :

PubMedSearch : Masai_2004_J.Bacteriol_186_2757

PubMedID: 15090517

Gene_locus related to this paper: psepa-q60fx2

Title : Tissue distribution of DDVP after fatal ingestion - Shimizu_1996_Forensic.Sci.Int_83_61

Author(s) : Shimizu K , Shiono H , Fukushima T , Sasaki M , Akutsu H , Sakata M

Ref : Forensic Science International , 83 :61 , 1996

Abstract :

PubMedSearch : Shimizu_1996_Forensic.Sci.Int_83_61

PubMedID: 8939014

Title : Longitudinal characteristic curve of liver disease - Kitazoe_1995_Comput.Biol.Med_25_39

Author(s) : Kitazoe Y , Kurihara Y , Okuhara Y , Onishi S , Tomita A , Yamamoto Y , Nishioka Y , Sasaki M , Yamamoto K , Nose Y

Ref : Computers in Biology & Medicine , 25 :39 , 1995

Abstract :

PubMedSearch : Kitazoe_1995_Comput.Biol.Med_25_39

PubMedID: 7600760

Sasaki M

References (17)

1. The mechanism of Atg15-mediated membrane disruption in autophagy - Kagohashi_2023_J.Cell.Biol_222_e202306120

2. Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models - Sasaki_2021_Arterioscler.Thromb.Vasc.Biol_41_360

3. Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__

4. Dipeptidyl Peptidase 9 Increases Chemoresistance and is an Indicator of Poor Prognosis in Colorectal Cancer - Saso_2020_Ann.Surg.Oncol_27_4337

5. Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase - Hattori_2019_J.Med.Chem_62_2362

6. Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors - Aida_2018_J.Med.Chem_61_9205

7. Decreased resting energy expenditure in patients with Duchenne muscular dystrophy - Shimizu-Fujiwara_2012_Brain.Dev_34_206

8. Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 - Banno_2011_Bioorg.Med.Chem_19_4953

9. Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554 - Maezaki_2011_Bioorg.Med.Chem_19_4482

10. Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831

11. Acetylcholinesterase activity, choline acetyltransferase and vesicular acetylcholine transporter immunoreactivities in the rat adrenal gland during postnatal development - Murabayashi_2009_Anat.Rec.(Hoboken)_292_371

12. Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic gamma-secretase inhibitors - Fuwa_2007_ACS.Chem.Biol_2_408

13. Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3 ,2,1-ij]quinolin-4-one (TAK-802) and related compounds - Ishichi_2005_Bioorg.Med.Chem_13_1901

14. Complete sequencing and characterization of 21,243 full-length human cDNAs - Ota_2004_Nat.Genet_36_40

15. A novel tetrahydrofolate-dependent O-demethylase gene is essential for growth of Sphingomonas paucimobilis SYK-6 with syringate - Masai_2004_J.Bacteriol_186_2757

16. Tissue distribution of DDVP after fatal ingestion - Shimizu_1996_Forensic.Sci.Int_83_61

17. Longitudinal characteristic curve of liver disease - Kitazoe_1995_Comput.Biol.Med_25_39