Gerdes JM

References (13)

Title : [(11)C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography (PET) Imaging in Rat - Hayes_2023_J.Pharmacol.Exp.Ther__
Author(s) : Hayes TR , Chao CK , Blecha JE , Huynh TL , VanBrocklin HF , Zinn KR , Gerdes JM , Thompson CM
Ref : Journal of Pharmacology & Experimental Therapeutics , : , 2023
Abstract :
PubMedSearch : Hayes_2023_J.Pharmacol.Exp.Ther__
PubMedID: 37770203

Title : Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats - Hayes_2021_Chem.Res.Toxicol_34_63
Author(s) : Hayes TR , Chao CK , Blecha JE , Huynh TL , Zinn KR , Thompson CM , Gerdes JM , VanBrocklin HF
Ref : Chemical Research in Toxicology , 34 :63 , 2021
Abstract :
PubMedSearch : Hayes_2021_Chem.Res.Toxicol_34_63
PubMedID: 33373198

Title : Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[(18) F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [(18) F]-VXS - Hayes_2020_Ann.N.Y.Acad.Sci__
Author(s) : Hayes TR , Blecha JE , Chao CK , Huynh TL , VanBrocklin HD , Zinn KR , Taylor P , Gerdes JM , Thompson CM
Ref : Annals of the New York Academy of Sciences , : , 2020
Abstract :
PubMedSearch : Hayes_2020_Ann.N.Y.Acad.Sci__
PubMedID: 32436233

Title : Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures - Thompson_2020_Neurobiol.Dis_133_104455
Author(s) : Thompson CM , Gerdes JM , VanBrocklin HF
Ref : Neurobiol Dis , 133 :104455 , 2020
Abstract :
PubMedSearch : Thompson_2020_Neurobiol.Dis_133_104455
PubMedID: 31022458

Title : Divergent synthesis of organophosphate [(11)C]VX- and [(11)C]Sarin-surrogates from a common set of starting materials - Hayes_2019_Appl.Radiat.Isot_151_182
Author(s) : Hayes TR , Blecha JE , Thompson CM , Gerdes JM , VanBrocklin HF
Ref : Appl Radiat Isot , 151 :182 , 2019
Abstract :
PubMedSearch : Hayes_2019_Appl.Radiat.Isot_151_182
PubMedID: 31202183

Title : Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [(11)C]2-Pyridinealdoxime Methiodide ([(11)C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication - Neumann_2018_ACS.Chem.Neurosci_9_3007
Author(s) : Neumann KD , Blecha JE , Hayes TR , Huynh T , Chao CK , Guilloteau N , Zinn KR , VanBrocklin HF , Thompson CM , Gerdes JM
Ref : ACS Chem Neurosci , 9 :3007 , 2018
Abstract :
PubMedSearch : Neumann_2018_ACS.Chem.Neurosci_9_3007
PubMedID: 30071719

Title : The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE - Chao_2018_Chem.Biol.Interact_291_220
Author(s) : Chao CK , Balasubramanian N , Gerdes JM , Thompson CM
Ref : Chemico-Biological Interactions , 291 :220 , 2018
Abstract :
PubMedSearch : Chao_2018_Chem.Biol.Interact_291_220
PubMedID: 29920286

Title : Radiosynthesis of O-(1-[(18) F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin - Hayes_2018_J.Labelled.Comp.Radiopharm_61_1089
Author(s) : Hayes TR , Thompson CM , Blecha JE , Gerdes JM , VanBrocklin HF
Ref : J Labelled Comp Radiopharm , 61 :1089 , 2018
Abstract :
PubMedSearch : Hayes_2018_J.Labelled.Comp.Radiopharm_61_1089
PubMedID: 30347484

Title : An improved radiosynthesis of O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A first-in-class cholinesterase PET tracer - Neumann_2017_J.Labelled.Comp.Radiopharm_60_337
Author(s) : Neumann KD , Thompson CM , Blecha JE , Gerdes JM , VanBrocklin HF
Ref : J Labelled Comp Radiopharm , 60 :337 , 2017
Abstract :
PubMedSearch : Neumann_2017_J.Labelled.Comp.Radiopharm_60_337
PubMedID: 28406525

Title : Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases - Chao_2016_Chem.Res.Toxicol_29_1810
Author(s) : Chao CK , Ahmed SK , Gerdes JM , Thompson CM
Ref : Chemical Research in Toxicology , 29 :1810 , 2016
Abstract :
PubMedSearch : Chao_2016_Chem.Res.Toxicol_29_1810
PubMedID: 27551891

Title : A Novel Fluorine-18 beta-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase - James_2014_ACS.Chem.Neurosci_5_519
Author(s) : James SL , Ahmed SK , Murphy S , Braden MR , Belabassi Y , VanBrocklin HF , Thompson CM , Gerdes JM
Ref : ACS Chem Neurosci , 5 :519 , 2014
Abstract :
PubMedSearch : James_2014_ACS.Chem.Neurosci_5_519
PubMedID: 24716794

Title : Synthesis and anti-acetylcholinesterase properties of novel beta- and gamma-substituted alkoxy organophosphonates - Kaleem_2013_Bioorg.Med.Chem.Lett_23_2048
Author(s) : Kaleem Ahmed S , Belabassi Y , Sankaranarayanan L , Chao CK , Gerdes JM , Thompson CM
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :2048 , 2013
Abstract :
PubMedSearch : Kaleem_2013_Bioorg.Med.Chem.Lett_23_2048
PubMedID: 23453838

Title : Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates - Guo_2010_Bioorg.Med.Chem.Lett_20_1194
Author(s) : Guo L , Suarez AI , Braden MR , Gerdes JM , Thompson CM
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1194 , 2010
Abstract :
PubMedSearch : Guo_2010_Bioorg.Med.Chem.Lett_20_1194
PubMedID: 20034789