| Title : Discovery of highly potent alpha-keto ester-based peptidomimetic inhibitors of the Hip1 protease for the treatment of Mycobacterium tuberculosis - Schumann_2025_Eur.J.Med.Chem.Rep_15_100311 |
| Author(s) : Schumann N , Shamma F , Brooks CL , Johnson SJ , Yim MK , Olsen KJ , Pena K , Karakousis PC , Abell A , Goldfarb NE |
| Ref : Eur J Med Chem Rep , 15 :100311 , 2025 |
| Abstract : |
| PubMedSearch : Schumann_2025_Eur.J.Med.Chem.Rep_15_100311 |
| PubMedID: |
| Title : Discovery of highly potent alpha-keto ester-based peptidomimetic inhibitors of the Hip1 protease for the treatment of Mycobacterium tuberculosis - Schumann_2025_Eur.J.Med.Chem.Rep_15_100311 |
| Author(s) : Schumann N , Shamma F , Brooks CL , Johnson SJ , Yim MK , Olsen KJ , Pena K , Karakousis PC , Abell A , Goldfarb NE |
| Ref : Eur J Med Chem Rep , 15 :100311 , 2025 |
| Abstract : |
| PubMedSearch : Schumann_2025_Eur.J.Med.Chem.Rep_15_100311 |
| PubMedID: |
| Title : Discovery of highly potent alpha-keto ester-based peptidomimetic inhibitors of the Hip1 protease for the treatment of Mycobacterium tuberculosis - Schumann_2025_Eur.J.Med.Chem.Rep_15_100311 |
| Author(s) : Schumann N , Shamma F , Brooks CL , Johnson SJ , Yim MK , Olsen KJ , Pena K , Karakousis PC , Abell A , Goldfarb NE |
| Ref : Eur J Med Chem Rep , 15 :100311 , 2025 |
| Abstract : |
| PubMedSearch : Schumann_2025_Eur.J.Med.Chem.Rep_15_100311 |
| PubMedID: |
| Title : 2.1 A crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1) - Brooks_2022_Biochem.Biophys.Res.Commun_630_57 |
| Author(s) : Brooks CL , Ostrov DA , Schumann NC , Kakkad S , Li D , Pena K , Williams BP , Goldfarb NE |
| Ref : Biochemical & Biophysical Research Communications , 630 :57 , 2022 |
| Abstract : |
| PubMedSearch : Brooks_2022_Biochem.Biophys.Res.Commun_630_57 |
| PubMedID: 36148729 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : 2.1 A crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1) - Brooks_2022_Biochem.Biophys.Res.Commun_630_57 |
| Author(s) : Brooks CL , Ostrov DA , Schumann NC , Kakkad S , Li D , Pena K , Williams BP , Goldfarb NE |
| Ref : Biochemical & Biophysical Research Communications , 630 :57 , 2022 |
| Abstract : |
| PubMedSearch : Brooks_2022_Biochem.Biophys.Res.Commun_630_57 |
| PubMedID: 36148729 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : 2.1 A crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1) - Brooks_2022_Biochem.Biophys.Res.Commun_630_57 |
| Author(s) : Brooks CL , Ostrov DA , Schumann NC , Kakkad S , Li D , Pena K , Williams BP , Goldfarb NE |
| Ref : Biochemical & Biophysical Research Communications , 630 :57 , 2022 |
| Abstract : |
| PubMedSearch : Brooks_2022_Biochem.Biophys.Res.Commun_630_57 |
| PubMedID: 36148729 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c) - Naffin-Olivos_2017_Biochemistry_56_2304 |
| Author(s) : Naffin-Olivos JL , Daab A , White A , Goldfarb NE , Milne AC , Liu D , Baikovitz J , Dunn BM , Rengarajan J , Petsko GA , Ringe D |
| Ref : Biochemistry , 56 :2304 , 2017 |
| Abstract : |
| PubMedSearch : Naffin-Olivos_2017_Biochemistry_56_2304 |
| PubMedID: 28346784 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c) - Naffin-Olivos_2017_Biochemistry_56_2304 |
| Author(s) : Naffin-Olivos JL , Daab A , White A , Goldfarb NE , Milne AC , Liu D , Baikovitz J , Dunn BM , Rengarajan J , Petsko GA , Ringe D |
| Ref : Biochemistry , 56 :2304 , 2017 |
| Abstract : |
| PubMedSearch : Naffin-Olivos_2017_Biochemistry_56_2304 |
| PubMedID: 28346784 |
| Gene_locus related to this paper: myctu-ym24 |
| Title : Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c) - Naffin-Olivos_2017_Biochemistry_56_2304 |
| Author(s) : Naffin-Olivos JL , Daab A , White A , Goldfarb NE , Milne AC , Liu D , Baikovitz J , Dunn BM , Rengarajan J , Petsko GA , Ringe D |
| Ref : Biochemistry , 56 :2304 , 2017 |
| Abstract : |
| PubMedSearch : Naffin-Olivos_2017_Biochemistry_56_2304 |
| PubMedID: 28346784 |
| Gene_locus related to this paper: myctu-ym24 |