Kewitz H

General

Full name : Kewitz Helmut || Kewitz Helmuth

First name : Helmut || Helmuth

Mail : Freie Universitat Berlin, Institut fur Klinische Pharmakologie, Hindenburgdamm 30, D-1000 Berlin 45

Zip Code :

City :

Country : Germany

Email :

Phone : 49 30 8016151

Fax : 49 30 8016151

Website : \/\/de.wikipedia.org\/wiki\/Helmut_Kewitz

Directory :

Comment
Helmut Kewitz was born 25. Juli 1920 in Berlin and died in Oktober 2009 in Berlin. As toxicologist in University of Columbia he tested on mice the 2-PAM (pralidoxime) a reactivator of cholinesterase synthetized by Dr. Sara Ginsburg and Dr. Irwin B. Wilson

References (26)

Title : The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6 - Bachus_1999_Pharmacogenet_9_661
Author(s) : Bachus R , Bickel U , Thomsen T , Roots I , Kewitz H
Ref : Pharmacogenetics , 9 :661 , 1999
Abstract :
PubMedSearch : Bachus_1999_Pharmacogenet_9_661
PubMedID: 10634129

Title : Inhibition of acetylcholinesterase activity in human brain tissue and erythrocytes by galanthamine, physostigmine and tacrine - Thomsen_1991_Eur.J.Clin.Chem.Clin.Biochem_29_487
Author(s) : Thomsen T , Kaden B , Fischer JP , Bickel U , Barz H , Gusztony G , Cervos-Navarro J , Kewitz H
Ref : European Journal of Clinical Chemistry & Clinical Biochemistry , 29 :487 , 1991
Abstract :
PubMedSearch : Thomsen_1991_Eur.J.Clin.Chem.Clin.Biochem_29_487
PubMedID: 1954303

Title : In vitro effects of various cholinesterase inhibitors on acetyl- and butyrylcholinesterase of healthy volunteers -
Author(s) : Thomsen T , Zendeh B , Fischer JP , Kewitz H
Ref : Biochemical Pharmacology , 41 :139 , 1991
PubMedID: 1986738

Title : Dose-related effects of nerve growth factor (NGF) on choline acetyltransferase (ChAT), acetylcholine (ACh) content and ACh turnover in the brain of newborn rats - Kewitz_1990_Neurochem.Int_17_239
Author(s) : Kewitz H , Rost KL , Pleul O , Handke A
Ref : Neurochem Int , 17 :239 , 1990
Abstract :
PubMedSearch : Kewitz_1990_Neurochem.Int_17_239
PubMedID: 20504624

Title : Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo - Thomsen_1990_Life.Sci_46_1553
Author(s) : Thomsen T , Kewitz H
Ref : Life Sciences , 46 :1553 , 1990
Abstract :
PubMedSearch : Thomsen_1990_Life.Sci_46_1553
PubMedID: 2355800

Title : A suitable method to monitor inhibition of cholinesterase activities in tissues as induced by reversible enzyme inhibitors - Thomsen_1989_Enzyme_42_219
Author(s) : Thomsen T , Kewitz H , Pleul O
Ref : Enzyme , 42 :219 , 1989
Abstract :
PubMedSearch : Thomsen_1989_Enzyme_42_219
PubMedID: 2698348

Title : Estimation of cholinesterase activity (EC 3.1.1.7\; 3.1.1.8) in undiluted plasma and erythrocytes as a tool for measuring in vivo effects of reversible inhibitors - Thomsen_1988_J.Clin.Chem.Clin.Biochem_26_469
Author(s) : Thomsen T , Kewitz H , Pleul O
Ref : J Clinical Chemistry Clinical Biochemistry , 26 :469 , 1988
Abstract :
PubMedSearch : Thomsen_1988_J.Clin.Chem.Clin.Biochem_26_469
PubMedID: 3065439

Title : Synthesis of Choline in the Brain -
Author(s) : Kewitz H , Pleul O
Ref : Advances in Behavioral Biology , 25 :405 , 1981
PubMedID:

Title : Inhibition of choline incorporation into brain lipids in rats by urethane, a proposed mechanism of depression of the central nervous system - Kewitz_1977_Naunyn.Schmiedebergs.Arch.Pharmacol_298_205
Author(s) : Kewitz H , Pleul O
Ref : Naunyn Schmiedebergs Arch Pharmacol , 298 :205 , 1977
Abstract :
PubMedSearch : Kewitz_1977_Naunyn.Schmiedebergs.Arch.Pharmacol_298_205
PubMedID: 895894

Title : Pre- and postnatal development and drug induced alterations of free and bound acetylcholine in rat brain -
Author(s) : Kewitz H , Pleul O , Mann E
Ref : Naunyn Schmiedebergs Arch Pharmacol , 298 :149 , 1977
PubMedID: 882153

Title : Synthesis of choline from ethanolamine in rat brain - Kewitz_1976_Proc.Natl.Acad.Sci.U.S.A_73_2181
Author(s) : Kewitz H , Pleul O
Ref : Proc Natl Acad Sci U S A , 73 :2181 , 1976
Abstract :
PubMedSearch : Kewitz_1976_Proc.Natl.Acad.Sci.U.S.A_73_2181
PubMedID: 1065868

Title : The supply of choline in rat brain -
Author(s) : Kewitz H , Pleul O , Dross K , Schwartzkopff T
Ref : Cholinergic.Mechanisms, Raven Press :131 , 1975
PubMedID:

Title : Concentration and origin of choline in the rat brain -
Author(s) : Dross K , Kewitz H
Ref : Naunyn Schmiedebergs Arch Pharmacol , 274 :91 , 1972
PubMedID: 4262729

Title : [A gas chromatographic determination of quaternary ammonium compounds (author's transl)] -
Author(s) : Vidic HJ , Dross H , Kewitz H
Ref : Z Klin Chem Klin Biochem , 10 :156 , 1972
PubMedID: 4681012

Title : [Separation of acetylcholine in the rat brain into 3 fractions and attempt at a functional classification] -
Author(s) : Kewitz H , Pleul O
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 263 :228 , 1969
PubMedID: 5804255

Title : Effect of cholinesterase inhibitors on the metabolism of acetylcholine in brain -
Author(s) : Dross K , Kewitz H
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 259 :206 , 1968
PubMedID: 4232689

Title : [Concentration of acetylcholine, choline and glycerylphosphorylcholine in the brain during anesthesia and in DFP poisoning] -
Author(s) : Dross K , Kewitz H
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 260 :107 , 1968
PubMedID: 4239148

Title : [Incorporation of choline into acetylcholine during narcosis and in DFP-poisoning] -
Author(s) : Dross K , Kewitz H
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 257 :13 , 1967
PubMedID: 4231829

Title : Reactivation of alkylphosphorylated cholinesterase by a constituent of liver -
Author(s) : Neuhoff V , Kewitz H
Ref : International Journal of Neuropharmacology , 1 :169 , 1962
PubMedID:

Title : Herstellung eines Trockenpreparates alkylphosphat-vergifteter Acetylcholinesterase fur Reaktivierungsversuche -
Author(s) : Kewitz H , Neuroff V
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 240 :126 , 1960
PubMedID: 13752817

Title : A specific antidote against lethal alkyl phosphate intoxication. IV. Effects in brain -
Author(s) : Kewitz H , Nachmansohn D
Ref : Archives of Biochemistry & Biophysics , 66 :271 , 1959
PubMedID:

Title : [Restoration of cholinesterase activity by a specific antidote in alkylphosphate poisoning] -
Author(s) : Kewitz H
Ref : Klin Wochenschr , 35 :521 , 1957
PubMedID: 13450257

Title : A specific antidote against lethal alkyl phosphate intoxication. IV. Effects in brain -
Author(s) : Kewitz H , Nachmansohn D
Ref : Archives of Biochemistry & Biophysics , 66 :271 , 1957
PubMedID: 13403673

Title : A specific antidote against lethal alkyl phosphate intoxication. II. Antidotal properties -
Author(s) : Kewitz H , Nachmansohn D , Wilson IB
Ref : Archives of Biochemistry & Biophysics , 64 :456 , 1956
PubMedID: 13363452

Title : [The significance of acetylcholine as transmitting substance of sympathetic ganglia] -
Author(s) : Kewitz H
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 222 :323 , 1954
PubMedID: 13185331

Title : [The differentiation between acetylcholine stimulation and transmission function of sympathetic ganglia by means of perfusion solutions of various composition] -
Author(s) : Kewitz H , Reinert H
Ref : Naunyn Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie , 222 :315 , 1954
PubMedID: 13185330