| Title : Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment - Zhang_2022_J.Med.Chem_65_13240 |
| Author(s) : Zhang W , Lun S , Wang SS , Cai YP , Yang F , Tang J , Bishai WR , Yu LF |
| Ref : Journal of Medicinal Chemistry , 65 :13240 , 2022 |
| Abstract : |
| PubMedSearch : Zhang_2022_J.Med.Chem_65_13240 |
| PubMedID: 36174223 |
| Gene_locus related to this paper: myctu-PKS13 |
| Title : Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules - Zhang_2021_Eur.J.Med.Chem_213_113202 |
| Author(s) : Zhang W , Liu LL , Lun S , Wang SS , Xiao S , Gunosewoyo H , Yang F , Tang J , Bishai WR , Yu LF |
| Ref : Eur Journal of Medicinal Chemistry , 213 :113202 , 2021 |
| Abstract : |
| PubMedSearch : Zhang_2021_Eur.J.Med.Chem_213_113202 |
| PubMedID: 33516983 |
| Gene_locus related to this paper: myctu-PKS13 |
| Title : Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II - Zhang_2019_J.Med.Chem_62_3575 |
| Author(s) : Zhang W , Lun S , Liu LL , Xiao S , Duan G , Gunosewoyo H , Yang F , Tang J , Bishai WR , Yu LF |
| Ref : Journal of Medicinal Chemistry , 62 :3575 , 2019 |
| Abstract : |
| PubMedSearch : Zhang_2019_J.Med.Chem_62_3575 |
| PubMedID: 30875203 |
| Gene_locus related to this paper: myctu-PKS13 |
| Title : Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis - Zhang_2018_J.Med.Chem_61_791 |
| Author(s) : Zhang W , Lun S , Wang SH , Jiang XW , Yang F , Tang J , Manson AL , Earl AM , Gunosewoyo H , Bishai WR , Yu LF |
| Ref : Journal of Medicinal Chemistry , 61 :791 , 2018 |
| Abstract : |
| PubMedSearch : Zhang_2018_J.Med.Chem_61_791 |
| PubMedID: 29328655 |
| Gene_locus related to this paper: myctu-PKS13 |
| Title : Characterization of a novel cell wall-anchored protein with carboxylesterase activity required for virulence in Mycobacterium tuberculosis - Lun_2007_J.Biol.Chem_282_18348 |
| Author(s) : Lun S , Bishai WR |
| Ref : Journal of Biological Chemistry , 282 :18348 , 2007 |
| Abstract : |
| PubMedSearch : Lun_2007_J.Biol.Chem_282_18348 |
| PubMedID: 17428787 |
| Gene_locus related to this paper: myctu-ym23 , myctu-ym24 |