| Title : Experimental Evaluation of QY-69: A Butyrylcholinesterase Inhibitor with Anti-Glioblastoma Efficacy - Wang_2025_Curr.Neuropharmacol__ |
| Author(s) : Wang K , Lu Z , Duan Y , He S , Lyu W , Liao Q , Li Q , Chen X , Li H |
| Ref : Curr Neuropharmacol , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_Curr.Neuropharmacol__ |
| PubMedID: 40626539 |
| Title : Experimental Evaluation of QY-69: A Butyrylcholinesterase Inhibitor with Anti-Glioblastoma Efficacy - Wang_2025_Curr.Neuropharmacol__ |
| Author(s) : Wang K , Lu Z , Duan Y , He S , Lyu W , Liao Q , Li Q , Chen X , Li H |
| Ref : Curr Neuropharmacol , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_Curr.Neuropharmacol__ |
| PubMedID: 40626539 |
| Title : Experimental Evaluation of QY-69: A Butyrylcholinesterase Inhibitor with Anti-Glioblastoma Efficacy - Wang_2025_Curr.Neuropharmacol__ |
| Author(s) : Wang K , Lu Z , Duan Y , He S , Lyu W , Liao Q , Li Q , Chen X , Li H |
| Ref : Curr Neuropharmacol , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_Curr.Neuropharmacol__ |
| PubMedID: 40626539 |
| Title : Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease - Chen_2024_Eur.J.Med.Chem_272_116463 |
| Author(s) : Chen Y , Zhang W , Li Q , Xie H , Xing S , Lu X , Lyu W , Xiong B , Wang Y , Qu W , Liu W , Chi H , Zhang X , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 272 :116463 , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_Eur.J.Med.Chem_272_116463 |
| PubMedID: 38704944 |
| Title : Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease - Chen_2024_Eur.J.Med.Chem_272_116463 |
| Author(s) : Chen Y , Zhang W , Li Q , Xie H , Xing S , Lu X , Lyu W , Xiong B , Wang Y , Qu W , Liu W , Chi H , Zhang X , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 272 :116463 , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_Eur.J.Med.Chem_272_116463 |
| PubMedID: 38704944 |
| Title : Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease - Chen_2024_Eur.J.Med.Chem_272_116463 |
| Author(s) : Chen Y , Zhang W , Li Q , Xie H , Xing S , Lu X , Lyu W , Xiong B , Wang Y , Qu W , Liu W , Chi H , Zhang X , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 272 :116463 , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_Eur.J.Med.Chem_272_116463 |
| PubMedID: 38704944 |
| Title : Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease - Wang_2022_Eur.J.Med.Chem_244_114806 |
| Author(s) : Wang Y , Xiong B , Lin H , Li Q , Yang H , Qiao Y , Xu Z , Lyu W , Qu W , Liu W , Chen Y , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 244 :114806 , 2022 |
| Abstract : |
| PubMedSearch : Wang_2022_Eur.J.Med.Chem_244_114806 |
| PubMedID: 36223681 |
| Title : N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease - Du_2022_J.Med.Chem__ |
| Author(s) : Du C , Wang L , Guan Q , Yang H , Chen T , Liu Y , Li Q , Lyu W , Lu X , Chen Y , Liu H , Feng F , Liu W , Liu Z , Li W , Sun H |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Du_2022_J.Med.Chem__ |
| PubMedID: 35969197 |
| Title : Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease - Wang_2022_Eur.J.Med.Chem_244_114806 |
| Author(s) : Wang Y , Xiong B , Lin H , Li Q , Yang H , Qiao Y , Xu Z , Lyu W , Qu W , Liu W , Chen Y , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 244 :114806 , 2022 |
| Abstract : |
| PubMedSearch : Wang_2022_Eur.J.Med.Chem_244_114806 |
| PubMedID: 36223681 |
| Title : N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease - Du_2022_J.Med.Chem__ |
| Author(s) : Du C , Wang L , Guan Q , Yang H , Chen T , Liu Y , Li Q , Lyu W , Lu X , Chen Y , Liu H , Feng F , Liu W , Liu Z , Li W , Sun H |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Du_2022_J.Med.Chem__ |
| PubMedID: 35969197 |
| Title : A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement - Li_2022_Eur.J.Med.Chem_239_114510 |
| Author(s) : Li Q , Xiong B , Wang Y , Lyu W , Xing S , Chen Y , Liao Q , He S , Feng F , Liu W , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 239 :114510 , 2022 |
| Abstract : |
| PubMedSearch : Li_2022_Eur.J.Med.Chem_239_114510 |
| PubMedID: 35728508 |
| Title : Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease - Wang_2022_Eur.J.Med.Chem_244_114806 |
| Author(s) : Wang Y , Xiong B , Lin H , Li Q , Yang H , Qiao Y , Xu Z , Lyu W , Qu W , Liu W , Chen Y , Feng F , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 244 :114806 , 2022 |
| Abstract : |
| PubMedSearch : Wang_2022_Eur.J.Med.Chem_244_114806 |
| PubMedID: 36223681 |
| Title : A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement - Li_2022_Eur.J.Med.Chem_239_114510 |
| Author(s) : Li Q , Xiong B , Wang Y , Lyu W , Xing S , Chen Y , Liao Q , He S , Feng F , Liu W , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 239 :114510 , 2022 |
| Abstract : |
| PubMedSearch : Li_2022_Eur.J.Med.Chem_239_114510 |
| PubMedID: 35728508 |
| Title : N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease - Du_2022_J.Med.Chem__ |
| Author(s) : Du C , Wang L , Guan Q , Yang H , Chen T , Liu Y , Li Q , Lyu W , Lu X , Chen Y , Liu H , Feng F , Liu W , Liu Z , Li W , Sun H |
| Ref : Journal of Medicinal Chemistry , : , 2022 |
| Abstract : |
| PubMedSearch : Du_2022_J.Med.Chem__ |
| PubMedID: 35969197 |
| Title : A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement - Li_2022_Eur.J.Med.Chem_239_114510 |
| Author(s) : Li Q , Xiong B , Wang Y , Lyu W , Xing S , Chen Y , Liao Q , He S , Feng F , Liu W , Sun H |
| Ref : Eur Journal of Medicinal Chemistry , 239 :114510 , 2022 |
| Abstract : |
| PubMedSearch : Li_2022_Eur.J.Med.Chem_239_114510 |
| PubMedID: 35728508 |
| Title : Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine - Jiang_2021_Eur.J.Med.Chem_223_113663 |
| Author(s) : Jiang X , Liu C , Zou M , Xie H , Lin T , Lyu W , Xu J , Li Y , Feng F , Sun H , Liu W |
| Ref : Eur Journal of Medicinal Chemistry , 223 :113663 , 2021 |
| Abstract : |
| PubMedSearch : Jiang_2021_Eur.J.Med.Chem_223_113663 |
| PubMedID: 34198150 |
| Title : Discovery of potent glycogen synthase kinase 3\/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease - Jiang_2021_Bioorg.Med.Chem_30_115940 |
| Author(s) : Jiang X , Wang Y , Liu C , Xing C , Lyu W , Wang S , Li Q , Chen T , Chen Y , Feng F , Liu W , Sun H |
| Ref : Bioorganic & Medicinal Chemistry , 30 :115940 , 2021 |
| Abstract : |
| PubMedSearch : Jiang_2021_Bioorg.Med.Chem_30_115940 |
| PubMedID: 33340937 |
| Title : Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine - Jiang_2021_Eur.J.Med.Chem_223_113663 |
| Author(s) : Jiang X , Liu C , Zou M , Xie H , Lin T , Lyu W , Xu J , Li Y , Feng F , Sun H , Liu W |
| Ref : Eur Journal of Medicinal Chemistry , 223 :113663 , 2021 |
| Abstract : |
| PubMedSearch : Jiang_2021_Eur.J.Med.Chem_223_113663 |
| PubMedID: 34198150 |
| Title : Discovery of potent glycogen synthase kinase 3\/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease - Jiang_2021_Bioorg.Med.Chem_30_115940 |
| Author(s) : Jiang X , Wang Y , Liu C , Xing C , Lyu W , Wang S , Li Q , Chen T , Chen Y , Feng F , Liu W , Sun H |
| Ref : Bioorganic & Medicinal Chemistry , 30 :115940 , 2021 |
| Abstract : |
| PubMedSearch : Jiang_2021_Bioorg.Med.Chem_30_115940 |
| PubMedID: 33340937 |
| Title : Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine - Jiang_2021_Eur.J.Med.Chem_223_113663 |
| Author(s) : Jiang X , Liu C , Zou M , Xie H , Lin T , Lyu W , Xu J , Li Y , Feng F , Sun H , Liu W |
| Ref : Eur Journal of Medicinal Chemistry , 223 :113663 , 2021 |
| Abstract : |
| PubMedSearch : Jiang_2021_Eur.J.Med.Chem_223_113663 |
| PubMedID: 34198150 |
| Title : Discovery of potent glycogen synthase kinase 3\/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease - Jiang_2021_Bioorg.Med.Chem_30_115940 |
| Author(s) : Jiang X , Wang Y , Liu C , Xing C , Lyu W , Wang S , Li Q , Chen T , Chen Y , Feng F , Liu W , Sun H |
| Ref : Bioorganic & Medicinal Chemistry , 30 :115940 , 2021 |
| Abstract : |
| PubMedSearch : Jiang_2021_Bioorg.Med.Chem_30_115940 |
| PubMedID: 33340937 |