Feng F

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Title : Neuroprotection by tetramethylpyrazine and its synthesized analogues for central nervous system diseases: a review - Feng_2024_Mol.Biol.Rep_51_159
Author(s) : Feng F , Xu DQ , Yue SJ , Chen YY , Tang YP
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Title : Optimizing drug-like properties of selective butyrylcholinesterase inhibitors for cognitive improvement: Enhancing aqueous solubility by disrupting molecular plane - Xing_2024_Eur.J.Med.Chem_268_116289
Author(s) : Xing S , Tang X , Wang L , Wang J , Lv B , Wang X , Guo C , Zhao Y , Feng F , Liu W , Chen Y , Sun H
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Title : Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease - Chen_2024_Eur.J.Med.Chem_272_116463
Author(s) : Chen Y , Zhang W , Li Q , Xie H , Xing S , Lu X , Lyu W , Xiong B , Wang Y , Qu W , Liu W , Chi H , Zhang X , Feng F , Sun H
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Title : Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease - Wang_2022_Eur.J.Med.Chem_244_114806
Author(s) : Wang Y , Xiong B , Lin H , Li Q , Yang H , Qiao Y , Xu Z , Lyu W , Qu W , Liu W , Chen Y , Feng F , Sun H
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Title : A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement - Li_2022_Eur.J.Med.Chem_239_114510
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Title : Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease - Lu_2022_Eur.J.Med.Chem_243_114729
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Title : N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease - Du_2022_J.Med.Chem__
Author(s) : Du C , Wang L , Guan Q , Yang H , Chen T , Liu Y , Li Q , Lyu W , Lu X , Chen Y , Liu H , Feng F , Liu W , Liu Z , Li W , Sun H
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Title : Synthesis and bio-evaluation of a novel selective butyrylcholinesterase inhibitor discovered through structure-based virtual screening - Xing_2021_Int.J.Biol.Macromol_166_1352
Author(s) : Xing S , Chen Y , Xiong B , Lu W , Li Q , Wang Y , Jiao M , Feng F , Liu W , Sun H
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Title : Structure and therapeutic uses of butyrylcholinesterase: Application in detoxification, Alzheimer's disease, and fat metabolism - Xing_2021_Med.Res.Rev_41_858
Author(s) : Xing S , Li Q , Xiong B , Chen Y , Feng F , Liu W , Sun H
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Title : Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine - Jiang_2021_Eur.J.Med.Chem_223_113663
Author(s) : Jiang X , Liu C , Zou M , Xie H , Lin T , Lyu W , Xu J , Li Y , Feng F , Sun H , Liu W
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Title : Discovery of potent glycogen synthase kinase 3\/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease - Jiang_2021_Bioorg.Med.Chem_30_115940
Author(s) : Jiang X , Wang Y , Liu C , Xing C , Lyu W , Wang S , Li Q , Chen T , Chen Y , Feng F , Liu W , Sun H
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Title : Synthesis and activity of miconazole derivatives as dual BChE\/IDO1 inhibitors for the treatment of Alzheimer's disease - Lu_2021_Future.Med.Chem_13_1105
Author(s) : Lu X , Liu Y , Qin N , Yang H , Qiao Y , Jiang X , Chen Y , Feng F , Liu W , Zhou Y , Sun H
Ref : Future Med Chem , 13 :1105 , 2021
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Title : Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection - Li_2021_J.Med.Chem__
Author(s) : Li Q , Chen Y , Xing S , Liao Q , Xiong B , Wang Y , Lu W , He S , Feng F , Liu W , Sun H
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Title : Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor - Li_2020_J.Med.Chem_63_10030
Author(s) : Li Q , Xing S , Chen Y , Liao Q , Xiong B , He S , Lu W , Liu Y , Yang H , Feng F , Liu W , Sun H
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PubMedID: 32787113

Title : Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases - Li_2020_Eur.J.Med.Chem_185_111862
Author(s) : Li Q , Xing S , Chen Y , Liao Q , Liu Y , He S , Feng F , Zhang J , Liu W , Guo Q , Sun Y , Sun H
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Title : Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease - Mo_2020_J.Enzyme.Inhib.Med.Chem_35_330
Author(s) : Mo J , Chen T , Yang H , Guo Y , Li Q , Qiao Y , Lin H , Feng F , Liu W , Chen Y , Liu Z , Sun H
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Title : Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease - Jiang_2020_Eur.J.Med.Chem_207_112751
Author(s) : Jiang X , Zhou J , Wang Y , Chen L , Duan Y , Huang J , Liu C , Chen Y , Liu W , Sun H , Feng F , Qu W
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Title : Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer's disease - Liao_2020_Bioorg.Chem_99_103844
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Title : Design, synthesis, biological evaluation, and molecular modeling studies of quinoline-ferulic acid hybrids as cholinesterase inhibitors - Mo_2019_Bioorg.Chem_93_103310
Author(s) : Mo J , Yang H , Chen T , Li Q , Lin H , Feng F , Liu W , Qu W , Guo Q , Chi H , Chen Y , Sun H
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Title : Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening - Yang_2019_Bioorg.Chem_92_103294
Author(s) : Yang H , Du C , Li Q , Chen T , Lu X , Feng F , Chen Y , Liu W , Sun H
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Title : Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo - Guo_2019_Bioorg.Chem_92_103258
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Ref : Bioorg Chem , 92 :103258 , 2019
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Title : Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation - Lu_2019_Bioorg.Chem_85_117
Author(s) : Lu X , Yang H , Li Q , Chen Y , Zhou Y , Feng F , Liu W , Guo Q , Sun H
Ref : Bioorg Chem , 85 :117 , 2018 || 2019
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Title : Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease - Lu_2018_Bioorg.Med.Chem_26_1665
Author(s) : Lu X , He SY , Li Q , Yang H , Jiang X , Lin H , Chen Y , Qu W , Feng F , Bian Y , Zhou Y , Sun H
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Title : Dual GSK-3beta\/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery - Jiang_2018_ACS.Med.Chem.Lett_9_171
Author(s) : Jiang XY , Chen TK , Zhou JT , He SY , Yang HY , Chen Y , Qu W , Feng F , Sun HP
Ref : ACS Med Chem Lett , 9 :171 , 2018
PubMedID: 29541355

Title : Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease - Li_2018_Eur.J.Med.Chem_158_463
Author(s) : Li Q , He S , Chen Y , Feng F , Qu W , Sun H
Ref : Eur Journal of Medicinal Chemistry , 158 :463 , 2018
PubMedID: 30243151

Title : Pentapeptide Prosequence Enhances Expression and Structure Folding of Recombinant Thermomyces lanuginosus Lipase in Pichia pastoris - Cai_2017_Protein.Pept.Lett_24_676
Author(s) : Cai H , Zhao M , Li Y , Mao J , Cai C , Feng F
Ref : Protein Pept Lett , 24 :676 , 2017
PubMedID: 28641563

Title : Continuous fluorometric assays for acetylcholinesterase activity and inhibition with conjugated polyelectrolytes -
Author(s) : Feng F , Tang Y , Wang S , Li Y , Zhu D
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