Nakatani S

Title : Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors - Takai_2015_Bioorg.Med.Chem.Lett_25_1705

Author(s) : Takai K , Chiyo N , Nakajima T , Nariai T , Ishikawa C , Nakatani S , Ikeno A , Yamamoto S , Sone T

Ref : Bioorganic & Medicinal Chemistry Lett , 25 :1705 , 2015

Abstract :

PubMedSearch : Takai_2015_Bioorg.Med.Chem.Lett_25_1705

PubMedID: 25800114

Gene_locus related to this paper: human-EPHX2

Title : Structure-based optimization of cyclopropyl urea derivatives as potent soluble epoxide hydrolase inhibitors for potential decrease of renal injury without hypotensive action - Takai_2014_Bioorg.Med.Chem_22_1548

Author(s) : Takai K , Nakajima T , Takanashi Y , Sone T , Nariai T , Chiyo N , Nakatani S , Ishikawa C , Yamaguchi N , Fujita K , Yamada K

Ref : Bioorganic & Medicinal Chemistry , 22 :1548 , 2014

Abstract :

PubMedSearch : Takai_2014_Bioorg.Med.Chem_22_1548

PubMedID: 24530032

Nakatani S

References (2)

1. Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors - Takai_2015_Bioorg.Med.Chem.Lett_25_1705

2. Structure-based optimization of cyclopropyl urea derivatives as potent soluble epoxide hydrolase inhibitors for potential decrease of renal injury without hypotensive action - Takai_2014_Bioorg.Med.Chem_22_1548